住宅靠近主要道路与过敏性呼吸结果的风险:一项系统综述和荟萃分析。

IF 11.3 2区 医学 Q1 ALLERGY
Qinchi Yu, Zihao Guo, Lijun Bai, Huimeng Liu, Cuiyao Xie, Dandan Liu, Yuxue Chang, Yaxin Wang, Ming Li, Jian Lei, Shaowei Wu
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引用次数: 0

摘要

随着全球城市化的加速,住宅靠近主要道路(RPMR)已被认为是对公共卫生的重大威胁,而道路靠近与过敏性呼吸道结局风险之间的关系尚不清楚。本研究旨在评估RPMR与过敏性呼吸结局风险之间的关系。我们对PubMed、EMBASE、Web of Science、Cochrane和Scopus数据库中现有的科学文献进行了系统的文献检索。研究方案在PROSPERO注册(注册ID: CRD42024604182)。通过计算合并优势比(OR)和相应的95%置信区间(CI),应用随机效应模型评估RPMR与过敏性呼吸结局风险之间的关联。在研究期间,纳入了55项符合条件的研究,包括373320名参与者。我们发现,接近的RPMR(≤200 m)与哮喘(OR = 1.23, 95% CI: 1.15, 1.31)、喘息(OR = 1.21, 95% CI: 1.12, 1.30)和鼻炎(OR = 1.22, 95% CI: 1.13, 1.32)的风险增加相关。此外,我们发现RPMR越接近,过敏呼吸道结果的风险越高。观察到的RPMR与过敏性呼吸道结局之间的关联在儿童和城市化程度较低的地区比在成人和高度城市化地区更为明显。我们的研究为RPMR与过敏性呼吸道结局风险之间的关联提供了全面的证据。研究结果可能有助于城市规划和公共卫生战略的实际意义,以减轻暴露于交通相关的污染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Residential Proximity to Major Roadways and Risk of Allergic Respiratory Outcomes: A Systematic Review and Meta-analysis.

With the acceleration of global urbanization, residential proximity to major roadways (RPMR) has been recognized as a significant threat to public health, while the association between road proximity and risks of allergic respiratory outcomes remains unclear. This study aims to evaluate the associations between RPMR and the risks of allergic respiratory outcomes. We conducted a systematic literature search for existing scientific literature from databases of PubMed, EMBASE, Web of Science, Cochrane, and Scopus. The study protocol was registered at PROSPERO (registration ID: CRD42024604182). Random effects models were applied to evaluate the associations between RPMR and the risks of allergic respiratory outcomes by calculating the pooled odds ratio (OR) and corresponding 95% confidence interval (CI). During the study periods, 55 eligible studies were included, comprising 373,320 participants. We found that a close RPMR (≤ 200 m) was associated with increased risks of asthma (OR = 1.23, 95% CI: 1.15, 1.31), wheezing (OR = 1.21, 95% CI: 1.12, 1.30), and rhinitis (OR = 1.22, 95% CI: 1.13, 1.32). In addition, we identified that the closer the RPMR, the higher the risks for allergic respiratory outcomes. The observed associations between RPMR and allergic respiratory outcomes were more pronounced among children and less urbanized areas than in adults and highly urbanized areas. Our study provides comprehensive evidence for the associations between RPMR and risks for allergic respiratory outcomes. The findings may contribute to the practical implications for urban planning and public health strategies to mitigate exposure to traffic-related pollution.

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来源期刊
CiteScore
22.30
自引率
1.10%
发文量
58
审稿时长
6-12 weeks
期刊介绍: Clinical Reviews in Allergy & Immunology is a scholarly journal that focuses on the advancement of clinical management in allergic and immunologic diseases. The journal publishes both scholarly reviews and experimental papers that address the current state of managing these diseases, placing new data into perspective. Each issue of the journal is dedicated to a specific theme of critical importance to allergists and immunologists, aiming to provide a comprehensive understanding of the subject matter for a wide readership. The journal is particularly helpful in explaining how novel data impacts clinical management, along with advancements such as standardized protocols for allergy skin testing and challenge procedures, as well as improved understanding of cell biology. Ultimately, the journal aims to contribute to the improvement of care and management for patients with immune-mediated diseases.
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