卫生保健工作者的致命药物过量:验尸官报告的专题框架分析。

IF 5.3 1区 医学 Q1 PSYCHIATRY
Addiction Pub Date : 2025-07-22 DOI:10.1111/add.70139
Thikra Algahtani, Siobhan Gee, Aminah Shah, Bryn D Williams, Hayley C Gorton, Sarah Welch, Caroline S Copeland
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引用次数: 0

摘要

背景和目的:由于医护人员获得药物、临床知识和工作压力的独特途径,他们面临药物过量的特殊脆弱性。本研究旨在了解卫生保健工作者致命过量用药的特点,以期为预防策略提供指导。设计、环境和病例:我们回顾性地确定了2000年至2022年间向国家物质使用死亡率规划报告的英格兰、威尔士和北爱尔兰的病例,这些病例的死者在死亡时正在医疗机构工作或学习,或者以前曾在医疗机构工作过。测量:进行了定量分析,以报告死者的简要人口统计、死亡情况和所涉药物。进行了定性专题框架分析,以确定和探索可能导致医疗保健专业人员致命药物过量的因素。结果:在确定的病例中,医生是最具代表性的职业(48%的病例,n = 28/58),阿片类药物是最常导致死亡的药物类别(43%的病例,n = 25/58)。虽然在确定的病例中很少有娱乐性药物使用的证据(n = 3),但医院专用药物的突出特征是29%的异丙酚(n = 17/58);10%为咪达唑仑(n = 6/58);神经肌肉阻滞剂占9% (n = 5/58)。定性分析确定了七个主题,包括从工作场所获取药物、静脉注射给药技能和/或设备的使用、获得私人处方、诊断出的精神健康状况、最近可能对精神健康产生负面影响的事件、慢性疼痛和自我用药以及药物使用障碍和/或过量用药史。结论:在英格兰、威尔士和北爱尔兰的卫生保健工作者中,致命药物过量的特征似乎不同于在英国使用药物的总体人群中观察到的特征。为防止此类死亡,重要的是卫生保健工作者能够获得针对其面临的具体挑战量身定制的护理和支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fatal drug overdoses in healthcare workers: A thematic framework analysis of coroner reports.

Background and aims: Healthcare workers face specific vulnerabilities for drug overdose due to their unique access to medications, clinical knowledge and work-related stress. This study aimed to understand the characteristics of fatal overdoses in healthcare workers with a view to providing guidance for preventative strategies.

Design, setting and cases: We retrospectively identified cases in England, Wales and Northern Ireland reported to the National Programme on Substance Use Mortality between 2000 and 2022 where decedents were working or studying within a healthcare setting at the time of their death or had previously worked in healthcare.

Measurements: Quantitative analyses were conducted to report summary demographics of decedents, the circumstances of deaths and the drugs involved. A qualitative thematic framework analysis was performed to identify and explore factors that may contribute to fatal drug overdose in healthcare professionals.

Findings: In the identified cases, doctors were the most represented profession (48% of cases, n = 28/58) with opioids the drug class most often implicated in causing death (43% of cases, n = 25/58). Whilst there was scant evidence of recreational drug use in the identified cases (n = 3), hospital-only medications prominently featured [propofol in 29% (n = 17/58); midazolam in 10% (n = 6/58); neuromuscular blocking agents in 9% (n = 5/58)]. Qualitative analysis identified seven themes including accessing drugs from the workplace, use of skills and/or equipment for intravenous drug administration, obtainment of private prescriptions, diagnosed mental health conditions, recent events likely to have negatively impacted mental health, chronic pain and self-medicating and history of substance use disorder and/or overdose.

Conclusions: The characteristics of fatal drug overdoses among healthcare workers in England, Wales and Northern Ireland appear to differ from those observed in the overall population of people who use drugs in the UK. To prevent such deaths, it is important that healthcare workers can access bespoke care and support tailored to the specific challenges that they face.

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来源期刊
Addiction
Addiction 医学-精神病学
CiteScore
10.80
自引率
6.70%
发文量
319
审稿时长
3 months
期刊介绍: Addiction publishes peer-reviewed research reports on pharmacological and behavioural addictions, bringing together research conducted within many different disciplines. Its goal is to serve international and interdisciplinary scientific and clinical communication, to strengthen links between science and policy, and to stimulate and enhance the quality of debate. We seek submissions that are not only technically competent but are also original and contain information or ideas of fresh interest to our international readership. We seek to serve low- and middle-income (LAMI) countries as well as more economically developed countries. Addiction’s scope spans human experimental, epidemiological, social science, historical, clinical and policy research relating to addiction, primarily but not exclusively in the areas of psychoactive substance use and/or gambling. In addition to original research, the journal features editorials, commentaries, reviews, letters, and book reviews.
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