Rose Bulteau, Lucie Barbier, Guillaume Lamour, Yassir Lemseffer, Marie-Hélène Verlhac, Nicolas Tessandier, Elsa Labrune, Martin Lenz, Marie-Emilie Terret, Clément Campillo
{"title":"原子力显微镜揭示小鼠和人类卵母细胞与皮质结构相关的机械特性差异（Small 29/2025）","authors":"Rose Bulteau, Lucie Barbier, Guillaume Lamour, Yassir Lemseffer, Marie-Hélène Verlhac, Nicolas Tessandier, Elsa Labrune, Martin Lenz, Marie-Emilie Terret, Clément Campillo","doi":"10.1002/smll.202570228","DOIUrl":null,"url":null,"abstract":"<p><b>Cell Mechanical Properties</b></p><p>In article number 2500221, Marie-Emilie Terret, Clément Campillo, and co-workers investigates the mechanical properties of mammalian oocytes using atomic force microscopy, and their relationship with the actin cortex structure, shown here in this confocal spinning disc image of a mouse oocyte cortex stained with an actin probe (SiR-Actin). It is shown that maternal age, a critical factor for fertility, affects mouse oocyte mechanics correlating with alterations in their cortex structure, and that the evolution of mechanical properties differs between human and mouse oocyte development, highlighting species-specific differences in cortex organization.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":228,"journal":{"name":"Small","volume":"21 29","pages":""},"PeriodicalIF":12.1000,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/smll.202570228","citationCount":"0","resultStr":"{\"title\":\"Atomic Force Microscopy Reveals Differences In Mechanical Properties Linked To Cortical Structure In Mouse And Human Oocytes (Small 29/2025)\",\"authors\":\"Rose Bulteau, Lucie Barbier, Guillaume Lamour, Yassir Lemseffer, Marie-Hélène Verlhac, Nicolas Tessandier, Elsa Labrune, Martin Lenz, Marie-Emilie Terret, Clément Campillo\",\"doi\":\"10.1002/smll.202570228\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>Cell Mechanical Properties</b></p><p>In article number 2500221, Marie-Emilie Terret, Clément Campillo, and co-workers investigates the mechanical properties of mammalian oocytes using atomic force microscopy, and their relationship with the actin cortex structure, shown here in this confocal spinning disc image of a mouse oocyte cortex stained with an actin probe (SiR-Actin). It is shown that maternal age, a critical factor for fertility, affects mouse oocyte mechanics correlating with alterations in their cortex structure, and that the evolution of mechanical properties differs between human and mouse oocyte development, highlighting species-specific differences in cortex organization.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":228,\"journal\":{\"name\":\"Small\",\"volume\":\"21 29\",\"pages\":\"\"},\"PeriodicalIF\":12.1000,\"publicationDate\":\"2025-07-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/smll.202570228\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Small\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/smll.202570228\",\"RegionNum\":2,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Small","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/smll.202570228","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
细胞力学特性在2500221号文章中，Marie-Emilie Terret、cl ment Campillo和同事们使用原子力显微镜研究了哺乳动物卵母细胞的力学特性，以及它们与肌动蛋白皮层结构的关系，这是用肌动蛋白探针（mr - actin）染色的小鼠卵母细胞皮层的共聚焦旋转圆盘图像。研究表明，母亲年龄是影响生育能力的关键因素，它会影响小鼠卵母细胞的力学特性，并与卵母细胞皮层结构的改变有关，而人类和小鼠卵母细胞发育过程中力学特性的进化存在差异，突出了皮层组织的物种特异性差异。
Atomic Force Microscopy Reveals Differences In Mechanical Properties Linked To Cortical Structure In Mouse And Human Oocytes (Small 29/2025)
Cell Mechanical Properties
In article number 2500221, Marie-Emilie Terret, Clément Campillo, and co-workers investigates the mechanical properties of mammalian oocytes using atomic force microscopy, and their relationship with the actin cortex structure, shown here in this confocal spinning disc image of a mouse oocyte cortex stained with an actin probe (SiR-Actin). It is shown that maternal age, a critical factor for fertility, affects mouse oocyte mechanics correlating with alterations in their cortex structure, and that the evolution of mechanical properties differs between human and mouse oocyte development, highlighting species-specific differences in cortex organization.
期刊介绍：
Small serves as an exceptional platform for both experimental and theoretical studies in fundamental and applied interdisciplinary research at the nano- and microscale. The journal offers a compelling mix of peer-reviewed Research Articles, Reviews, Perspectives, and Comments.
With a remarkable 2022 Journal Impact Factor of 13.3 (Journal Citation Reports from Clarivate Analytics, 2023), Small remains among the top multidisciplinary journals, covering a wide range of topics at the interface of materials science, chemistry, physics, engineering, medicine, and biology.
Small's readership includes biochemists, biologists, biomedical scientists, chemists, engineers, information technologists, materials scientists, physicists, and theoreticians alike.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
