吸气肌训练增强帕金森病患者对直立应激的心脏自主神经反应：一项初步研究

IF 3.3 4区医学 Q2 NEUROSCIENCES

Autonomic Neuroscience-Basic & Clinical Pub Date : 2025-07-21 DOI:10.1016/j.autneu.2025.103334

Felipe Castro Ferreira , Michelle Cristina Salabert Vaz Padilha , Pedro Paulo da Silva Soares , Marco Antônio Araujo-Leite , Gabriel Dias Rodrigues

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引用次数: 0

摘要

在这项初步研究中，8名帕金森病患者（PD）和8名年龄匹配的健康对照者完成了为期5周的家庭吸气肌训练（IMT）计划。在IMT之前和之后评估坐姿时的最大吸气压力和心率变异性（SIT）和直立压力。两组均表现出更好的最大吸气压力和迷走神经调节。然而，只有PD患者在直立应激时表现出增强的心脏自主调节。这些发现表明，IMT可能改善PD患者对直立应激的心脏自主神经反应，值得进一步研究。

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Inspiratory muscle training enhances cardiac autonomic response to orthostatic stress in patients with Parkinson's disease: a preliminary study

In this pilot study, eight patients with Parkinson's disease (PD) and eight age-matched healthy controls completed a 5-week home-based inspiratory muscle training (IMT) program. Maximal inspiratory pressure and heart rate variability during sitting (SIT) and orthostatic stress were assessed before and after IMT. Both groups exhibited better maximal inspiratory pressure and vagal modulation of the heart in the SIT position post-IMT. However, only patients with PD showed enhanced cardiac autonomic modulation during orthostatic stress. These findings suggest that IMT may improve the cardiac autonomic response to orthostatic stress in patients with PD, warranting further investigation.

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来源期刊

Autonomic Neuroscience-Basic & Clinical 医学-神经科学

CiteScore

5.80

自引率

7.40%

发文量

审稿时长

66 days

期刊介绍： This is an international journal with broad coverage of all aspects of the autonomic nervous system in man and animals. The main areas of interest include the innervation of blood vessels and viscera, autonomic ganglia, efferent and afferent autonomic pathways, and autonomic nuclei and pathways in the central nervous system. The Editors will consider papers that deal with any aspect of the autonomic nervous system, including structure, physiology, pharmacology, biochemistry, development, evolution, ageing, behavioural aspects, integrative role and influence on emotional and physical states of the body. Interdisciplinary studies will be encouraged. Studies dealing with human pathology will be also welcome.