{"title":"使用非结构化电子健康记录识别腹主动脉瘤修复的自然语言处理框架。","authors":"Daniel C Thompson, Reza Mofidi","doi":"10.1038/s41598-025-11870-6","DOIUrl":null,"url":null,"abstract":"<p><p>Patient identification for national registries often relies upon clinician recognition of cases or retrospective searches using potentially inaccurate clinical codes, leading to incomplete data capture and inefficiencies. Natural Language Processing (NLP) offers a promising solution by automating analysis of electronic health records (EHRs). This study aimed to develop NLP models for identifying and classifying abdominal aortic aneurysm (AAA) repairs from unstructured EHRs, demonstrating a proof-of-concept for automated patient identification in registries like the National Vascular Registry. Using the MIMIC-IV-Note dataset, a multi-tiered approach was developed to identify vascular patients (Task 1), AAA repairs (Task 2), and classify repairs as primary or revision (Task 3). Four NLP models were trained and evaluated using 4870 annotated records: scispaCy, BERT-base, Bio-clinicalBERT, and a scispaCy/Bio-clinicalBERT ensemble. Models were compared using accuracy, precision, recall, F1-score, and area under the receiver operating characteristic curve (AUC). The scispaCy model demonstrated the fastest training (2 min/epoch) and inference times (2.87 samples/sec). For Task 1, scispaCy and ensemble models achieved the highest accuracy (0.97). In Task 2, all models performed exceptionally well, with ensemble, scispaCy, and Bio-clinicalBERT models achieving 0.99 accuracy and 1.00 AUC. For Task 3, Bio-clinicalBERT and the ensemble model achieved an AUC of 1.00, with Bio-clinicalBERT displaying the best overall accuracy (0.98). This study demonstrates that NLP models can accurately identify and classify AAA repair cases from unstructured EHRs, suggesting significant potential for automating patient identification in vascular surgery and other medical registries, reducing administra.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"26388"},"PeriodicalIF":3.9000,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280078/pdf/","citationCount":"0","resultStr":"{\"title\":\"Natural Language Processing framework for identifying abdominal aortic aneurysm repairs using unstructured electronic health records.\",\"authors\":\"Daniel C Thompson, Reza Mofidi\",\"doi\":\"10.1038/s41598-025-11870-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Patient identification for national registries often relies upon clinician recognition of cases or retrospective searches using potentially inaccurate clinical codes, leading to incomplete data capture and inefficiencies. Natural Language Processing (NLP) offers a promising solution by automating analysis of electronic health records (EHRs). This study aimed to develop NLP models for identifying and classifying abdominal aortic aneurysm (AAA) repairs from unstructured EHRs, demonstrating a proof-of-concept for automated patient identification in registries like the National Vascular Registry. Using the MIMIC-IV-Note dataset, a multi-tiered approach was developed to identify vascular patients (Task 1), AAA repairs (Task 2), and classify repairs as primary or revision (Task 3). Four NLP models were trained and evaluated using 4870 annotated records: scispaCy, BERT-base, Bio-clinicalBERT, and a scispaCy/Bio-clinicalBERT ensemble. Models were compared using accuracy, precision, recall, F1-score, and area under the receiver operating characteristic curve (AUC). The scispaCy model demonstrated the fastest training (2 min/epoch) and inference times (2.87 samples/sec). For Task 1, scispaCy and ensemble models achieved the highest accuracy (0.97). In Task 2, all models performed exceptionally well, with ensemble, scispaCy, and Bio-clinicalBERT models achieving 0.99 accuracy and 1.00 AUC. For Task 3, Bio-clinicalBERT and the ensemble model achieved an AUC of 1.00, with Bio-clinicalBERT displaying the best overall accuracy (0.98). This study demonstrates that NLP models can accurately identify and classify AAA repair cases from unstructured EHRs, suggesting significant potential for automating patient identification in vascular surgery and other medical registries, reducing administra.</p>\",\"PeriodicalId\":21811,\"journal\":{\"name\":\"Scientific Reports\",\"volume\":\"15 1\",\"pages\":\"26388\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-07-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280078/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Scientific Reports\",\"FirstCategoryId\":\"103\",\"ListUrlMain\":\"https://doi.org/10.1038/s41598-025-11870-6\",\"RegionNum\":2,\"RegionCategory\":\"综合性期刊\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MULTIDISCIPLINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scientific Reports","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1038/s41598-025-11870-6","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
Natural Language Processing framework for identifying abdominal aortic aneurysm repairs using unstructured electronic health records.
Patient identification for national registries often relies upon clinician recognition of cases or retrospective searches using potentially inaccurate clinical codes, leading to incomplete data capture and inefficiencies. Natural Language Processing (NLP) offers a promising solution by automating analysis of electronic health records (EHRs). This study aimed to develop NLP models for identifying and classifying abdominal aortic aneurysm (AAA) repairs from unstructured EHRs, demonstrating a proof-of-concept for automated patient identification in registries like the National Vascular Registry. Using the MIMIC-IV-Note dataset, a multi-tiered approach was developed to identify vascular patients (Task 1), AAA repairs (Task 2), and classify repairs as primary or revision (Task 3). Four NLP models were trained and evaluated using 4870 annotated records: scispaCy, BERT-base, Bio-clinicalBERT, and a scispaCy/Bio-clinicalBERT ensemble. Models were compared using accuracy, precision, recall, F1-score, and area under the receiver operating characteristic curve (AUC). The scispaCy model demonstrated the fastest training (2 min/epoch) and inference times (2.87 samples/sec). For Task 1, scispaCy and ensemble models achieved the highest accuracy (0.97). In Task 2, all models performed exceptionally well, with ensemble, scispaCy, and Bio-clinicalBERT models achieving 0.99 accuracy and 1.00 AUC. For Task 3, Bio-clinicalBERT and the ensemble model achieved an AUC of 1.00, with Bio-clinicalBERT displaying the best overall accuracy (0.98). This study demonstrates that NLP models can accurately identify and classify AAA repair cases from unstructured EHRs, suggesting significant potential for automating patient identification in vascular surgery and other medical registries, reducing administra.
期刊介绍:
We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections.
Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021).
•Engineering
Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live.
•Physical sciences
Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics.
•Earth and environmental sciences
Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems.
•Biological sciences
Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants.
•Health sciences
The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.