环境抗生素耐药基因生物传感技术研究进展

IF 12 1区化学 Q1 CHEMISTRY, ANALYTICAL

Trends in Analytical Chemistry Pub Date : 2025-07-17 DOI:10.1016/j.trac.2025.118380

Fangqi Wu , Qi Zhu , Liang Zhang , Wei Shen , Jingming Gong , Hian Kee Lee , Sheng Tang

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引用次数: 0

摘要

抗生素的广泛使用导致环境中出现抗生素耐药菌（ARB）及其耐药基因（arg），构成向人类传播的风险。这一趋势使治疗复杂化，需要有效的ARG检测方法来诊断疾病和预防耐药性。鉴于现实世界检测环境的挑战，推进生物检测技术以精确识别ARGs至关重要。尽管有许多关于ARG检测的报道，但仍然缺乏用于ARG检测的生物传感器的全面审查。本文综述了用于ARGs评价和监测的生物传感器的分类和应用的最新研究进展，包括电化学传感器、光热传感器和量热传感器。综述了环境中ARGs的分类和特征，并详细讨论了生物传感器检测ARGs的机理和应用。本文综述旨在为ARGs的生物检测方法提供全面的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Recent progress of biosensing techniques for environmental antibiotic resistance genes

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Recent progress of biosensing techniques for environmental antibiotic resistance genes

The widespread use of antibiotics has led to the emergence of antibiotic resistant bacteria (ARB) and their resistance genes (ARGs) in the environment, posing a risk of transmission to humans. This trend complicates treatment and necessitates effective ARG detection methods for disease diagnosis and resistance prevention. Given the challenges of real-world detection environments, advancing biological detection technologies for precise identification of ARGs is crucial. Despite numerous reports on ARG detection, a comprehensive review of biosensors for ARG detection remains lacking. This review aims to introduce the latest research progress in the classification and application of biosensors for evaluating and monitoring ARGs, including electrochemical, photothermal and calorimetric sensors. The classification and characteristics of ARGs in the environment are summarized, and the mechanism and application of biosensors for detecting ARGs are discussed in detail. This review serves to supply comprehensive insights into biological detection methods for ARGs.

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来源期刊

Trends in Analytical Chemistry 化学-分析化学

CiteScore

20.00

自引率

4.60%

发文量

257

审稿时长

3.4 months

期刊介绍： TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.