{"title":"基于mof的酶和纳米酶生物传感器用于农药检测","authors":"Yijie Wang , Hongxia Li , Xu Yan","doi":"10.1016/j.trac.2025.118381","DOIUrl":null,"url":null,"abstract":"<div><div>The prevailing trend in contemporary agricultural development is the adoption of smart agriculture, which heavily relies on precise pesticide management and monitoring to ensure crop health and environmental safety. In this context, the effectiveness of pesticide detection is directly related to the sustainability of agricultural production. Traditional strategies for pesticide detection still face challenges such as complicated operations and time-consuming processes, necessitating the development of more efficient detection methods. Recent advancements have seen the development of composites integrating metal-organic frameworks (MOFs) and enzymes, which leverage the strengths of both components to demonstrate remarkable catalytic activity and stability, thereby enhancing the efficacy of pesticide detection. In this review, the recent progress of MOF-based enzyme/nanozyme composites is systematically summarized in terms of the encapsulation modes of natural enzymes by MOFs and the catalytic type by MOFs as nanozymes. Furthermore, the applications of MOF-based enzyme/nanozyme composites in pesticide detection are reviewed. Based on this, the current challenges and future perspectives are discussed. It is desired that the review can provide further insights into the rational design of enzyme and nanozyme pesticide biosensors based on MOFs, thereby contributing to the advancement of smart agriculture.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118381"},"PeriodicalIF":11.8000,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enzyme and nanozyme biosensors based on MOFs for pesticide detection\",\"authors\":\"Yijie Wang , Hongxia Li , Xu Yan\",\"doi\":\"10.1016/j.trac.2025.118381\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The prevailing trend in contemporary agricultural development is the adoption of smart agriculture, which heavily relies on precise pesticide management and monitoring to ensure crop health and environmental safety. In this context, the effectiveness of pesticide detection is directly related to the sustainability of agricultural production. Traditional strategies for pesticide detection still face challenges such as complicated operations and time-consuming processes, necessitating the development of more efficient detection methods. Recent advancements have seen the development of composites integrating metal-organic frameworks (MOFs) and enzymes, which leverage the strengths of both components to demonstrate remarkable catalytic activity and stability, thereby enhancing the efficacy of pesticide detection. In this review, the recent progress of MOF-based enzyme/nanozyme composites is systematically summarized in terms of the encapsulation modes of natural enzymes by MOFs and the catalytic type by MOFs as nanozymes. Furthermore, the applications of MOF-based enzyme/nanozyme composites in pesticide detection are reviewed. Based on this, the current challenges and future perspectives are discussed. It is desired that the review can provide further insights into the rational design of enzyme and nanozyme pesticide biosensors based on MOFs, thereby contributing to the advancement of smart agriculture.</div></div>\",\"PeriodicalId\":439,\"journal\":{\"name\":\"Trends in Analytical Chemistry\",\"volume\":\"191 \",\"pages\":\"Article 118381\"},\"PeriodicalIF\":11.8000,\"publicationDate\":\"2025-07-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Analytical Chemistry\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0165993625002493\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993625002493","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Enzyme and nanozyme biosensors based on MOFs for pesticide detection
The prevailing trend in contemporary agricultural development is the adoption of smart agriculture, which heavily relies on precise pesticide management and monitoring to ensure crop health and environmental safety. In this context, the effectiveness of pesticide detection is directly related to the sustainability of agricultural production. Traditional strategies for pesticide detection still face challenges such as complicated operations and time-consuming processes, necessitating the development of more efficient detection methods. Recent advancements have seen the development of composites integrating metal-organic frameworks (MOFs) and enzymes, which leverage the strengths of both components to demonstrate remarkable catalytic activity and stability, thereby enhancing the efficacy of pesticide detection. In this review, the recent progress of MOF-based enzyme/nanozyme composites is systematically summarized in terms of the encapsulation modes of natural enzymes by MOFs and the catalytic type by MOFs as nanozymes. Furthermore, the applications of MOF-based enzyme/nanozyme composites in pesticide detection are reviewed. Based on this, the current challenges and future perspectives are discussed. It is desired that the review can provide further insights into the rational design of enzyme and nanozyme pesticide biosensors based on MOFs, thereby contributing to the advancement of smart agriculture.
期刊介绍:
TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.