用于生物传感器和生物医学的氮化硼纳米片

IF 12 1区化学 Q1 CHEMISTRY, ANALYTICAL

Trends in Analytical Chemistry Pub Date : 2025-07-17 DOI:10.1016/j.trac.2025.118379

Guohai Yang , Luqing Chen , Jihan Liu , Yan Liu , Lulu Qu , Chengzhou Zhu , Jun-Jie Zhu , Yuehe Lin , Xiaochen Dong

{"title":"用于生物传感器和生物医学的氮化硼纳米片","authors":"Guohai Yang , Luqing Chen , Jihan Liu , Yan Liu , Lulu Qu , Chengzhou Zhu , Jun-Jie Zhu , Yuehe Lin , Xiaochen Dong","doi":"10.1016/j.trac.2025.118379","DOIUrl":null,"url":null,"abstract":"<div><div>The rapid development of advanced functional nanomaterials offers a robust foundation for exploring high-performance biosensing and biomedicine platforms. Boron nitride nanosheets (BNNS), atomically thin hexagonal boron nitride, have attracted significant attention due to outstanding chemical and thermal stability, excellent biocompatibility, and fascinating catalytic properties. Integrating doping and functionalization give BNNS-based materials significant potential in the fields of biosensors and biomedicine. This review firstly describes the structural features and overview of the prevailing preparation methods of BNNS. The following sections focus on the BNNS-based nanomaterials applications in biosensors. Additionally, the review addresses key biomedical applications of BNNS-based nanomaterials in drug delivery, boron neutron capture therapy (BNCT), and antibacterial treatments. Finally, the challenges faced by BNNS in these areas and potential pathways for future explorations are discussed. This review is expected to stimulate strategic advances in the use of BNNS for biosensors and biomedicine, thereby providing promising avenues for practical implementation.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118379"},"PeriodicalIF":12.0000,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Boron nitride nanosheets for biosensors and biomedicine\",\"authors\":\"Guohai Yang , Luqing Chen , Jihan Liu , Yan Liu , Lulu Qu , Chengzhou Zhu , Jun-Jie Zhu , Yuehe Lin , Xiaochen Dong\",\"doi\":\"10.1016/j.trac.2025.118379\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The rapid development of advanced functional nanomaterials offers a robust foundation for exploring high-performance biosensing and biomedicine platforms. Boron nitride nanosheets (BNNS), atomically thin hexagonal boron nitride, have attracted significant attention due to outstanding chemical and thermal stability, excellent biocompatibility, and fascinating catalytic properties. Integrating doping and functionalization give BNNS-based materials significant potential in the fields of biosensors and biomedicine. This review firstly describes the structural features and overview of the prevailing preparation methods of BNNS. The following sections focus on the BNNS-based nanomaterials applications in biosensors. Additionally, the review addresses key biomedical applications of BNNS-based nanomaterials in drug delivery, boron neutron capture therapy (BNCT), and antibacterial treatments. Finally, the challenges faced by BNNS in these areas and potential pathways for future explorations are discussed. This review is expected to stimulate strategic advances in the use of BNNS for biosensors and biomedicine, thereby providing promising avenues for practical implementation.</div></div>\",\"PeriodicalId\":439,\"journal\":{\"name\":\"Trends in Analytical Chemistry\",\"volume\":\"191 \",\"pages\":\"Article 118379\"},\"PeriodicalIF\":12.0000,\"publicationDate\":\"2025-07-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Analytical Chemistry\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S016599362500247X\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S016599362500247X","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}

引用次数: 0

摘要

先进功能纳米材料的快速发展为探索高性能生物传感和生物医学平台提供了坚实的基础。氮化硼纳米片（BNNS）是一种原子薄的六方氮化硼纳米片，由于其优异的化学稳定性、热稳定性、生物相容性和催化性能而备受关注。掺杂和功能化的结合使得基于bnns的材料在生物传感器和生物医学领域具有巨大的潜力。本文首先介绍了BNNS的结构特点和主要制备方法。下面几节重点介绍了基于bnns的纳米材料在生物传感器中的应用。此外，本文还介绍了基于bnns的纳米材料在药物递送、硼中子捕获治疗（BNCT）和抗菌治疗等方面的关键生物医学应用。最后，讨论了BNNS在这些领域面临的挑战和未来探索的潜在途径。这一综述有望促进生物传感器和生物医学中使用BNNS的战略进展，从而为实际实施提供有希望的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Boron nitride nanosheets for biosensors and biomedicine

查看原文本刊更多论文

Boron nitride nanosheets for biosensors and biomedicine

The rapid development of advanced functional nanomaterials offers a robust foundation for exploring high-performance biosensing and biomedicine platforms. Boron nitride nanosheets (BNNS), atomically thin hexagonal boron nitride, have attracted significant attention due to outstanding chemical and thermal stability, excellent biocompatibility, and fascinating catalytic properties. Integrating doping and functionalization give BNNS-based materials significant potential in the fields of biosensors and biomedicine. This review firstly describes the structural features and overview of the prevailing preparation methods of BNNS. The following sections focus on the BNNS-based nanomaterials applications in biosensors. Additionally, the review addresses key biomedical applications of BNNS-based nanomaterials in drug delivery, boron neutron capture therapy (BNCT), and antibacterial treatments. Finally, the challenges faced by BNNS in these areas and potential pathways for future explorations are discussed. This review is expected to stimulate strategic advances in the use of BNNS for biosensors and biomedicine, thereby providing promising avenues for practical implementation.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Trends in Analytical Chemistry 化学-分析化学

CiteScore

20.00

自引率

4.60%

发文量

257

审稿时长

3.4 months

期刊介绍： TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.