动脉粥样硬化切除术和血管内碎石术在经皮冠状动脉介入治疗中的应用差异

Kyu Lee MD , Priya Roy MD , Umair Ahmad MD , Paul S. Chan MSc, MD , Richard J. Gumina MD, PhD , Kevin Kennedy MSc , Vittal Hejjaji MSc, MD , Ali O. Malik MSc, MD
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引用次数: 0

摘要

背景:导管切除术和血管内碎石术(IVL)有助于钙化冠状动脉疾病的经皮冠状动脉介入治疗(PCI),使用这些技术可获得更大的管腔增益和更好的介入成功率。随着动脉粥样硬化切除术/IVL获得更广泛的接受,了解它们的使用是否因社会剥夺水平而异是很重要的。方法:在国家心血管数据注册中心(CathPCI)注册中心,我们确定了2018年至2023年期间接受严重钙化病变PCI治疗的310,124例患者。对于每位患者,我们根据其居住的邮政编码确定其社会剥夺指数(SDI)。SDI是衡量地区社会剥夺程度的综合指标,其数值越高,剥夺程度越严重。分层逻辑回归模型评估了SDI与动脉粥样硬化切除术/IVL的关系。结果患者平均年龄70.9±10.6岁,男性69.4%,白种人82.3%。33.0%的严重钙化动脉pci患者采用了动脉粥样硬化切除术/IVL。SDI与动脉粥样硬化切除术/IVL的使用呈负相关,呈分级关系。在调整患者和PCI特征后,这些差异仅部分减弱。与居住在社会剥夺最低四分位数社区的人相比,居住在社会剥夺最低四分位数社区的人占10%(优势比,0.90;95% ci, 0.88-0.92;P & lt;.001)和8%(优势比0.92;95% ci, 0.90-0.94;P & lt;.001),在PCI期间使用动脉粥样硬化切除术/IVL的可能性较小。结论:在美国,对于严重钙化的冠状动脉狭窄,更大的社会剥夺与更低的PCI中动脉粥样硬化切除术/IVL率相关,这突出了这些技术使用的潜在差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Disparities in the Use of Atherectomy and Intravascular Lithotripsy for Percutaneous Coronary Intervention

Background

Atherectomy and intravascular lithotripsy (IVL) facilitate percutaneous coronary intervention (PCI) in calcified coronary disease, and use of these technologies is associated with greater luminal gain and superior intervention success. As atherectomy/IVL gain more widespread acceptance, it is important to understand whether their use differs across levels of social deprivation.

Methods

Within the National Cardiovascular Data Registry CathPCI Registry, we identified 310,124 patients who had a PCI for severely calcified lesions between 2018 and 2023. For each patient, we determined their social deprivation index (SDI) based on residential zip codes. The SDI is a composite measure of area-level social deprivation, with higher values correlating to greater deprivation. Hierarchical logistic regression models evaluated the association of SDI with use of atherectomy/IVL.

Results

Mean age was 70.9 ± 10.6 years, 69.4% were men, and 82.3% were of White race. Atherectomy/IVL was used in 33.0% of PCIs in severely calcified arteries. There was an inverse, graded relationship between SDI and atherectomy/IVL use. These differences were only partially attenuated after adjusting for patient and PCI characteristics. Compared with those residing in neighborhoods with the lowest quartile of social deprivation, those in the third and fourth quartiles of social deprivation were 10% (odds ratio, 0.90; 95% CI, 0.88-0.92; P < .001) and 8% (odds ratio, 0.92; 95% CI, 0.90-0.94; P < .001), respectively, less likely to have atherectomy/IVL used during PCI.

Conclusions

In the United States, greater social deprivation was associated with lower rates of atherectomy/IVL during PCI for severely calcified coronary artery stenoses, highlighting potential disparities in use of these technologies.
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