{"title":"时间分辨近红外光谱透射模式监测极低出生体重儿深部脑组织。","authors":"Toshiyuki Imanishi, Wakako Sumiya, Chika Kanno, Masayuki Kanno, Ken Kawabata, Masaki Shimizu","doi":"10.1111/apa.70245","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>To investigate the potential of the transmittance mode of time-resolved near-infrared spectroscopy, in which the source and detector probes are placed on the bilateral temporal region of the head, compared with the conventional reflectance mode in extremely low-birth-weight (ELBW) infants.</p><p><strong>Methods: </strong>Differences in cerebral tissue oxygen saturation (StO<sub>2</sub>) and cerebral blood volume (CBV) between the two modes were evaluated. Linear regression was performed to investigate contributing factors to StO<sub>2</sub> and CBV.</p><p><strong>Results: </strong>Forty-nine ELBW infants (median gestational age, 24.9 weeks; mean birthweight, 672 g), including nine intraventricular haemorrhage (IVH) cases, were evaluated at a median of 14.0 days of age. StO<sub>2</sub> and CBV values were significantly lower in the transmittance mode than in the reflectance mode. IVH was a significant contributor to StO<sub>2</sub> and CBV. Two out of four cases with IVH grade 3 had larger ventricular dilations and showed outliers towards low StO<sub>2</sub>.</p><p><strong>Conclusion: </strong>The transmittance mode detected lower StO<sub>2</sub> in ELBW infants as compared to the reflectance mode, especially in IVH cases. This was either due to the optical effects of the IVH itself and/or large dilated ventricles.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transmittance Mode of Time-Resolved Near-Infrared Spectroscopy for Monitoring Deeper Cerebral Tissues in Extremely Low-Birth-Weight Infants.\",\"authors\":\"Toshiyuki Imanishi, Wakako Sumiya, Chika Kanno, Masayuki Kanno, Ken Kawabata, Masaki Shimizu\",\"doi\":\"10.1111/apa.70245\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>To investigate the potential of the transmittance mode of time-resolved near-infrared spectroscopy, in which the source and detector probes are placed on the bilateral temporal region of the head, compared with the conventional reflectance mode in extremely low-birth-weight (ELBW) infants.</p><p><strong>Methods: </strong>Differences in cerebral tissue oxygen saturation (StO<sub>2</sub>) and cerebral blood volume (CBV) between the two modes were evaluated. Linear regression was performed to investigate contributing factors to StO<sub>2</sub> and CBV.</p><p><strong>Results: </strong>Forty-nine ELBW infants (median gestational age, 24.9 weeks; mean birthweight, 672 g), including nine intraventricular haemorrhage (IVH) cases, were evaluated at a median of 14.0 days of age. StO<sub>2</sub> and CBV values were significantly lower in the transmittance mode than in the reflectance mode. IVH was a significant contributor to StO<sub>2</sub> and CBV. Two out of four cases with IVH grade 3 had larger ventricular dilations and showed outliers towards low StO<sub>2</sub>.</p><p><strong>Conclusion: </strong>The transmittance mode detected lower StO<sub>2</sub> in ELBW infants as compared to the reflectance mode, especially in IVH cases. This was either due to the optical effects of the IVH itself and/or large dilated ventricles.</p>\",\"PeriodicalId\":55562,\"journal\":{\"name\":\"Acta Paediatrica\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-07-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Paediatrica\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/apa.70245\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Paediatrica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/apa.70245","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PEDIATRICS","Score":null,"Total":0}
Transmittance Mode of Time-Resolved Near-Infrared Spectroscopy for Monitoring Deeper Cerebral Tissues in Extremely Low-Birth-Weight Infants.
Aim: To investigate the potential of the transmittance mode of time-resolved near-infrared spectroscopy, in which the source and detector probes are placed on the bilateral temporal region of the head, compared with the conventional reflectance mode in extremely low-birth-weight (ELBW) infants.
Methods: Differences in cerebral tissue oxygen saturation (StO2) and cerebral blood volume (CBV) between the two modes were evaluated. Linear regression was performed to investigate contributing factors to StO2 and CBV.
Results: Forty-nine ELBW infants (median gestational age, 24.9 weeks; mean birthweight, 672 g), including nine intraventricular haemorrhage (IVH) cases, were evaluated at a median of 14.0 days of age. StO2 and CBV values were significantly lower in the transmittance mode than in the reflectance mode. IVH was a significant contributor to StO2 and CBV. Two out of four cases with IVH grade 3 had larger ventricular dilations and showed outliers towards low StO2.
Conclusion: The transmittance mode detected lower StO2 in ELBW infants as compared to the reflectance mode, especially in IVH cases. This was either due to the optical effects of the IVH itself and/or large dilated ventricles.
期刊介绍：
Acta Paediatrica is a peer-reviewed monthly journal at the forefront of international pediatric research. It covers both clinical and experimental research in all areas of pediatrics including:
neonatal medicine
developmental medicine
adolescent medicine
child health and environment
psychosomatic pediatrics
child health in developing countries
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