{"title":"埃塞俄比亚孕妇乙型肝炎病毒感染的流行及其相关因素：2003年至2024年发表的数据的系统回顾和荟萃分析","authors":"Sintayehu Tsegaye Bitew, Yeshiwas Genanaw Mekonnen, Habtamu Belay Hailu","doi":"10.1186/s13690-025-01666-5","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Numerous epidemiological studies on hepatitis B virus among pregnant women in Ethiopia have been conducted, showing significant variation over time and between different geographical regions. The aim of this systematic review and Meta-analysis is to estimate the overall prevalence of hepatitis B virus infection and its associated factors among pregnant women in Ethiopia.</p><p><strong>Methods: </strong>We use the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for articles. All observational published studies were retrieved using relevant search terms PubMed, Embase, web of science and google scholar databases. Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instruments for observational studies was used for critical appraisal of the included articles. The meta-analysis was done with STATA version 18 software. The I<sup>2</sup> statistics were used to test heterogeneity whereas Begg's and Egger's tests were used to assess publication bias. The pooled prevalence was presented using the forest plot.</p><p><strong>Results: </strong>Forty -three studies with a total of 17,056 participants were included in this systematic review and meta-analysis. The pooled prevalence of the HBV infection among pregnant women was 6%(95% CI: 5.0, 7.0). a high pooled prevalence HBV infection among pregnant women was found in Tigray 7%(95% CI: 4.0, 8.0) and Somali region 7%(95% CI: 4.0, 11.0). history of surgical procedure, having multiple sexual partners, history of body tattooing, history of abortion, history of sharing sharp material, blood transfusion and family history of HBV were significant risk factors associated with HBV among pregnant women in Ethiopia.</p><p><strong>Conclusion: </strong>In conclusion, this systematic review and meta-analysis provided evidence regarding the intermediate prevalence of HBV among pregnant women in Ethiopia and also showed history of surgical procedures, multiple sexual partners, body tattooing, sharing sharp objects, abortion, blood transfusions, and family history of HBV infection were associated factors. The findings highlight the need of health education to prevent the spread of HBV infection among pregnant women.</p>","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":"83 1","pages":"191"},"PeriodicalIF":3.2000,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12278681/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prevalence of hepatitis B virus infection and its associated factors among pregnant women in Ethiopia: a systematic review and meta-analysis of data published from 2003 to 2024.\",\"authors\":\"Sintayehu Tsegaye Bitew, Yeshiwas Genanaw Mekonnen, Habtamu Belay Hailu\",\"doi\":\"10.1186/s13690-025-01666-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Numerous epidemiological studies on hepatitis B virus among pregnant women in Ethiopia have been conducted, showing significant variation over time and between different geographical regions. The aim of this systematic review and Meta-analysis is to estimate the overall prevalence of hepatitis B virus infection and its associated factors among pregnant women in Ethiopia.</p><p><strong>Methods: </strong>We use the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for articles. All observational published studies were retrieved using relevant search terms PubMed, Embase, web of science and google scholar databases. Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instruments for observational studies was used for critical appraisal of the included articles. The meta-analysis was done with STATA version 18 software. The I<sup>2</sup> statistics were used to test heterogeneity whereas Begg's and Egger's tests were used to assess publication bias. The pooled prevalence was presented using the forest plot.</p><p><strong>Results: </strong>Forty -three studies with a total of 17,056 participants were included in this systematic review and meta-analysis. The pooled prevalence of the HBV infection among pregnant women was 6%(95% CI: 5.0, 7.0). a high pooled prevalence HBV infection among pregnant women was found in Tigray 7%(95% CI: 4.0, 8.0) and Somali region 7%(95% CI: 4.0, 11.0). history of surgical procedure, having multiple sexual partners, history of body tattooing, history of abortion, history of sharing sharp material, blood transfusion and family history of HBV were significant risk factors associated with HBV among pregnant women in Ethiopia.</p><p><strong>Conclusion: </strong>In conclusion, this systematic review and meta-analysis provided evidence regarding the intermediate prevalence of HBV among pregnant women in Ethiopia and also showed history of surgical procedures, multiple sexual partners, body tattooing, sharing sharp objects, abortion, blood transfusions, and family history of HBV infection were associated factors. The findings highlight the need of health education to prevent the spread of HBV infection among pregnant women.</p>\",\"PeriodicalId\":48578,\"journal\":{\"name\":\"Archives of Public Health\",\"volume\":\"83 1\",\"pages\":\"191\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-07-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12278681/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Public Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s13690-025-01666-5\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Public Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s13690-025-01666-5","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
摘要
背景：对埃塞俄比亚孕妇中乙型肝炎病毒进行了大量流行病学研究，显示出不同时间和不同地理区域之间的显著差异。本系统综述和荟萃分析的目的是估计埃塞俄比亚孕妇中乙型肝炎病毒感染的总体流行率及其相关因素。方法：我们对文章使用系统评价和荟萃分析（PRISMA）指南的首选报告项目。所有已发表的观察性研究均使用相关搜索词PubMed、Embase、web of science和谷歌学者数据库进行检索。乔安娜布里格斯研究所统计荟萃分析评估和回顾工具用于观察性研究对纳入的文章进行批判性评价。meta分析采用STATA version 18软件进行。I2统计量用于检验异质性，而Begg’s和Egger’s检验用于评估发表偏倚。用森林样地表示合并流行率。结果：本系统综述和荟萃分析纳入了43项研究，共17,056名受试者。孕妇中HBV感染的总流行率为6%（95% CI: 5.0, 7.0）。提格雷地区（7%,95% CI: 4.0, 8.0）和索马里地区（7%,95% CI: 4.0, 11.0）的孕妇HBV感染率较高。手术史、多个性伴侣史、身体文身史、流产史、共用尖锐材料史、输血史和HBV家族史是埃塞俄比亚孕妇感染HBV的重要危险因素。结论：总而言之，本系统综述和荟萃分析为埃塞俄比亚孕妇中HBV的中等患病率提供了证据，并显示手术史、多性伴侣、身体纹身、共用尖锐物品、流产、输血和HBV感染家族史是相关因素。研究结果强调了健康教育的必要性，以防止乙型肝炎病毒感染在孕妇中传播。
Prevalence of hepatitis B virus infection and its associated factors among pregnant women in Ethiopia: a systematic review and meta-analysis of data published from 2003 to 2024.
Background: Numerous epidemiological studies on hepatitis B virus among pregnant women in Ethiopia have been conducted, showing significant variation over time and between different geographical regions. The aim of this systematic review and Meta-analysis is to estimate the overall prevalence of hepatitis B virus infection and its associated factors among pregnant women in Ethiopia.
Methods: We use the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for articles. All observational published studies were retrieved using relevant search terms PubMed, Embase, web of science and google scholar databases. Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instruments for observational studies was used for critical appraisal of the included articles. The meta-analysis was done with STATA version 18 software. The I2 statistics were used to test heterogeneity whereas Begg's and Egger's tests were used to assess publication bias. The pooled prevalence was presented using the forest plot.
Results: Forty -three studies with a total of 17,056 participants were included in this systematic review and meta-analysis. The pooled prevalence of the HBV infection among pregnant women was 6%(95% CI: 5.0, 7.0). a high pooled prevalence HBV infection among pregnant women was found in Tigray 7%(95% CI: 4.0, 8.0) and Somali region 7%(95% CI: 4.0, 11.0). history of surgical procedure, having multiple sexual partners, history of body tattooing, history of abortion, history of sharing sharp material, blood transfusion and family history of HBV were significant risk factors associated with HBV among pregnant women in Ethiopia.
Conclusion: In conclusion, this systematic review and meta-analysis provided evidence regarding the intermediate prevalence of HBV among pregnant women in Ethiopia and also showed history of surgical procedures, multiple sexual partners, body tattooing, sharing sharp objects, abortion, blood transfusions, and family history of HBV infection were associated factors. The findings highlight the need of health education to prevent the spread of HBV infection among pregnant women.
期刊介绍：
rchives of Public Health is a broad scope public health journal, dedicated to publishing all sound science in the field of public health. The journal aims to better the understanding of the health of populations. The journal contributes to public health knowledge, enhances the interaction between research, policy and practice and stimulates public health monitoring and indicator development. The journal considers submissions on health outcomes and their determinants, with clear statements about the public health and policy implications. Archives of Public Health welcomes methodological papers (e.g., on study design and bias), papers on health services research, health economics, community interventions, and epidemiological studies dealing with international comparisons, the determinants of inequality in health, and the environmental, behavioural, social, demographic and occupational correlates of health and diseases.
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