{"title":"双腔灌吸管治疗弥散性富尼耶坏疽的作用：一项单中心回顾性队列研究","authors":"Yuan-Zhi Li, Qing-Qiang Gao","doi":"10.21037/tau-2025-248","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The double-lumen irrigation-suction tube (DLIST) has demonstrated excellent efficacy in the treatment of complex infectious diseases; however, its application value in disseminated Fournier's gangrene (FG) remains undetermined. This research aims to assess the clinical efficacy and feasibility of DLIST in the treatment of disseminated FG.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinical data of 34 patients with disseminated FG admitted from October 2012 to February 2025. The severity of the disease was evaluated using the Fournier's Gangrene Severity Index (FGSI) and the modified Uludag Fournier's Gangrene Severity Index (UFGSI). The patients were divided into the DLIST group (group A) and the conventional dressing change group (group B) according to whether the DLIST technique was used after debridement. Data from the two groups were compared and analyzed.</p><p><strong>Results: </strong>Sixteen patients were treated with DLIST irrigation and suction, and 18 patients were treated with conventional dressing changes. No statistically significant differences were observed in FGSI and UFGSI scores between the two groups (P=0.49 and P=0.28, respectively). Compared with the conventional group, the DLIST group had significantly shorter wound closure time, lower daily gauze change frequency, reduced analgesic use frequency, and lower visual analogue scale scores (P=0.02, P<0.001, P<0.001, and P=0.02, respectively). The length of hospital stay (LOS) was also significantly shorter in the DLIST group (P=0.02). No deaths occurred in either group during the observation period.</p><p><strong>Conclusions: </strong>The application of DLIST after debridement significantly shortens wound closure time and LOS in patients with disseminated FG, while reducing dressing change frequency and alleviating pain. However, these results require further validation through large-scale, prospective, randomized controlled trials.</p>","PeriodicalId":23270,"journal":{"name":"Translational andrology and urology","volume":"14 6","pages":"1520-1527"},"PeriodicalIF":1.7000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12271950/pdf/","citationCount":"0","resultStr":"{\"title\":\"The role of double-lumen irrigation-suction tube in the treatment of disseminated Fournier's gangrene: a single-center retrospective cohort study.\",\"authors\":\"Yuan-Zhi Li, Qing-Qiang Gao\",\"doi\":\"10.21037/tau-2025-248\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The double-lumen irrigation-suction tube (DLIST) has demonstrated excellent efficacy in the treatment of complex infectious diseases; however, its application value in disseminated Fournier's gangrene (FG) remains undetermined. This research aims to assess the clinical efficacy and feasibility of DLIST in the treatment of disseminated FG.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinical data of 34 patients with disseminated FG admitted from October 2012 to February 2025. The severity of the disease was evaluated using the Fournier's Gangrene Severity Index (FGSI) and the modified Uludag Fournier's Gangrene Severity Index (UFGSI). The patients were divided into the DLIST group (group A) and the conventional dressing change group (group B) according to whether the DLIST technique was used after debridement. Data from the two groups were compared and analyzed.</p><p><strong>Results: </strong>Sixteen patients were treated with DLIST irrigation and suction, and 18 patients were treated with conventional dressing changes. No statistically significant differences were observed in FGSI and UFGSI scores between the two groups (P=0.49 and P=0.28, respectively). Compared with the conventional group, the DLIST group had significantly shorter wound closure time, lower daily gauze change frequency, reduced analgesic use frequency, and lower visual analogue scale scores (P=0.02, P<0.001, P<0.001, and P=0.02, respectively). The length of hospital stay (LOS) was also significantly shorter in the DLIST group (P=0.02). No deaths occurred in either group during the observation period.</p><p><strong>Conclusions: </strong>The application of DLIST after debridement significantly shortens wound closure time and LOS in patients with disseminated FG, while reducing dressing change frequency and alleviating pain. However, these results require further validation through large-scale, prospective, randomized controlled trials.</p>\",\"PeriodicalId\":23270,\"journal\":{\"name\":\"Translational andrology and urology\",\"volume\":\"14 6\",\"pages\":\"1520-1527\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12271950/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Translational andrology and urology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.21037/tau-2025-248\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/6/26 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"ANDROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Translational andrology and urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21037/tau-2025-248","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/26 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ANDROLOGY","Score":null,"Total":0}
The role of double-lumen irrigation-suction tube in the treatment of disseminated Fournier's gangrene: a single-center retrospective cohort study.
Background: The double-lumen irrigation-suction tube (DLIST) has demonstrated excellent efficacy in the treatment of complex infectious diseases; however, its application value in disseminated Fournier's gangrene (FG) remains undetermined. This research aims to assess the clinical efficacy and feasibility of DLIST in the treatment of disseminated FG.
Methods: A retrospective analysis was conducted on the clinical data of 34 patients with disseminated FG admitted from October 2012 to February 2025. The severity of the disease was evaluated using the Fournier's Gangrene Severity Index (FGSI) and the modified Uludag Fournier's Gangrene Severity Index (UFGSI). The patients were divided into the DLIST group (group A) and the conventional dressing change group (group B) according to whether the DLIST technique was used after debridement. Data from the two groups were compared and analyzed.
Results: Sixteen patients were treated with DLIST irrigation and suction, and 18 patients were treated with conventional dressing changes. No statistically significant differences were observed in FGSI and UFGSI scores between the two groups (P=0.49 and P=0.28, respectively). Compared with the conventional group, the DLIST group had significantly shorter wound closure time, lower daily gauze change frequency, reduced analgesic use frequency, and lower visual analogue scale scores (P=0.02, P<0.001, P<0.001, and P=0.02, respectively). The length of hospital stay (LOS) was also significantly shorter in the DLIST group (P=0.02). No deaths occurred in either group during the observation period.
Conclusions: The application of DLIST after debridement significantly shortens wound closure time and LOS in patients with disseminated FG, while reducing dressing change frequency and alleviating pain. However, these results require further validation through large-scale, prospective, randomized controlled trials.
期刊介绍：
ranslational Andrology and Urology (Print ISSN 2223-4683; Online ISSN 2223-4691; Transl Androl Urol; TAU) is an open access, peer-reviewed, bi-monthly journal (quarterly published from Mar.2012 - Dec. 2014). The main focus of the journal is to describe new findings in the field of translational research of Andrology and Urology, provides current and practical information on basic research and clinical investigations of Andrology and Urology. Specific areas of interest include, but not limited to, molecular study, pathology, biology and technical advances related to andrology and urology. Topics cover range from evaluation, prevention, diagnosis, therapy, prognosis, rehabilitation and future challenges to urology and andrology. Contributions pertinent to urology and andrology are also included from related fields such as public health, basic sciences, education, sociology, and nursing.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
