甲氧氯普胺致青少年急性肌张力障碍1例。

IF 1.5 4区医学 Q4 PHARMACOLOGY & PHARMACY

Indian Journal of Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-07-21 DOI:10.4103/ijp.ijp_884_24

K Jagadish Kumar, Shivani Kundur, Lalitha Vasudha Bulusu, H R Nandish, Prisha Mehta

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引用次数: 0

摘要

甲氧氯普胺是一种多巴胺-2拮抗剂，在临床实践中通常用作止吐药。甲氧氯普胺的主要不良反应是锥体外系反应，据报道占0.2%的病例。在幼儿中，发病率可高达25%。甲氧氯丙胺诱导的EPS包括急性肌张力障碍、迟发性运动障碍、帕金森病、静坐症和恶性抗精神病药综合征。我们报告了一例单剂量甲氧氯普胺引起的青春期女孩急性肌张力障碍，这引起了患者和对口服苯海拉明有反应的父母的大量焦虑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Metoclopramide-induced acute dystonia in an adolescent.

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Metoclopramide-induced acute dystonia in an adolescent.

Metoclopramide is a dopamine-2 antagonist and is generally used as an antiemetic in clinical practice. Extrapyramidal reactions are the important adverse effects of metoclopramide which are reported in 0.2% of cases. In young children, the incidence can extend up to 25%. Metoclopramide-induced EPS include acute dystonia, tardive dyskinesia, parkinsonism, akathisia, and malignant neuroleptic syndrome. We are reporting a single dose of metoclopramide induced acute dystonia in an adolescent girl, which caused lot of anxiety in the patient and the parents which responded to oral diphenhydramine.

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来源期刊

Indian Journal of Pharmacology 医学-药学

CiteScore

4.00

自引率

4.20%

发文量

审稿时长

4-8 weeks

期刊介绍： Indian Journal of Pharmacology accepts, in English, review articles, articles for educational forum, original research articles (full length and short communications), letter to editor, case reports and interesting fillers. Articles concerning all aspects of pharmacology will be considered. Articles of general interest (e.g. methods, therapeutics, medical education, interesting websites, new drug information and commentary on a recent topic) are also welcome.