医学吸入石蜡油致外源性脂质性肺炎1例并文献复习。

IF 3.1 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Frontiers in Medicine Pub Date : 2025-07-04 eCollection Date: 2025-01-01 DOI:10.3389/fmed.2025.1596160
Mingshuang Li, Conglin Ren, Cangsong Chen
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引用次数: 0

摘要

本病例报告描述一例外源性脂质性肺炎(ELP)由于医学吸石蜡油。一名87岁男性因卧床不起,吞咽困难住院。在给予鼻用石蜡油两天后,病人出现高烧和呼吸窘迫。血气分析显示,房间空气中的PaCO2为33 mmHg。胸部CT示多发磨玻璃影伴实性病灶。随后患者行支气管镜检查,支气管肺泡灌洗液(BALF)中发现大量油性混浊液。进一步的BALF细胞学分析显示35%的吞噬细胞,60%的中性粒细胞和5%的淋巴细胞。根据石蜡油暴露史、胸部CT成像和细胞学检查,诊断为ELP。尽管我们进行了积极的抗炎和抗感染治疗,但患者最终还是因高龄和多重并发症而去世。吸入油性物质是ELP最重要的危险因素。对于用药不当的高危人群,合适的鼻肠管更适合喂养和用药。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exogenous lipoid pneumonia due to medical aspiration of paraffin oil: a case report and literature review.

This case report describes a case of exogenous lipoid pneumonia (ELP) due to medical aspiration of paraffin oil. An 87-year-old male was hospitalized with bedridden, dysphagic dysphagia. Two days after being given nasal paraffin oil, the patient developed high fever and respiratory distress. Blood gas analysis showed a PaCO2 of 33 mmHg in the room air. CT scan of the chest showed multiple ground glass opacity with solid lesions. The patient then underwent bronchoscopy, and large quantities of oily turbid fluid was found in the bronchoalveolar lavage fluid (BALF). Further cytological analysis of the BALF showed 35% phagocytes, 60% neutrophils, and 5% lymphocytes. The patient was diagnosed with ELP based on a history of paraffin oil exposure, CT imaging of the chest, and cytological examination. Despite our aggressive anti-inflammatory and anti-infective treatment, the patient eventually passed away due to advanced age and multiple complications. Aspiration of oily substances is the most important risk factor for ELP. For people at high risk of misadministration, a suitable naso-intestinal tube is more appropriate for feeding and medication.

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来源期刊
Frontiers in Medicine
Frontiers in Medicine Medicine-General Medicine
CiteScore
5.10
自引率
5.10%
发文量
3710
审稿时长
12 weeks
期刊介绍: Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate - the use of patient-reported outcomes under real world conditions - the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines - the scientific bases for guidelines and decisions from regulatory authorities - access to medicinal products and medical devices worldwide - addressing the grand health challenges around the world
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