1999-2020年美国脑血管疾病和药物使用相关死亡率上升趋势CDC WONDER的回顾性分析。

IF 1.5 3区 医学 Q3 CLINICAL NEUROLOGY
Anosh John, Faraz Azhar, Zishan Rahman, Dmitry Abramov
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引用次数: 0

摘要

背景:由于多种病理生理改变,物质使用(SU)与脑血管疾病有关。本研究探讨了年龄、种族和人口统计学相关的美国成人(≥25岁)伴有SU和脑血管疾病的死亡率趋势。方法:采用CDC WONDER数据库获取死亡率数据。计算每10万人的年龄调整死亡率(AAMR)。使用Joinpoint回归分析计算年龄、性别、种族、州、死亡地点、普查区域和大都市状态的趋势,以及AAMR的年百分比变化(APC)。结果:1999 - 2020年共发生57,838例死亡,总AAMR为1.23。AAMRs最高的是45-64岁的成年人(1.8)、男性(1.85)、非西班牙裔(NH)美洲印第安人/阿拉斯加原住民(3.23)、哥伦比亚特区(2.78)和非大都市地区(1.35)。结论:心血管疾病与脑血管疾病相关的死亡率上升具有明显的社会人口统计学差异和时间差异,需要进一步研究和早期干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rising Trends in Cerebrovascular Disease and Substance Use-Related Mortality in the USA from 1999 to 2020: A Retrospective Analysis Using CDC WONDER.

Introduction: Substance use (SU) has been linked to cerebrovascular disease due to numerous pathophysiologic alterations. This study discusses the age, race, and demographics-related trends in mortality among US adults (≥25 years) with concomitant SU and cerebrovascular disease.

Methods: The CDC WONDER database was used to access the mortality data. Age-adjusted mortality rates (AAMRs) per 100,000 population were calculated. Trends for age, sex, race, state, place of death, census region, and metropolitan status, along with annual percent change (APC) in AAMR, were calculated using the Joinpoint regression analysis.

Results: From 1999 to 2020, 57,838 deaths occurred, with an overall AAMR of 1.23. The highest AAMRs were observed in adults aged 45-64 (1.8), men (1.85), the non-Hispanic American Indian/Alaska Native population (3.23), the District of Columbia (2.78), and nonmetropolitan areas (1.35).

Conclusion: The rising mortality related to SU and cerebrovascular disease with notable sociodemographic and temporal disparities calls for further research and early interventions.

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来源期刊
Cerebrovascular Diseases
Cerebrovascular Diseases 医学-临床神经学
CiteScore
4.50
自引率
0.00%
发文量
90
审稿时长
1 months
期刊介绍: A rapidly-growing field, stroke and cerebrovascular research is unique in that it involves a variety of specialties such as neurology, internal medicine, surgery, radiology, epidemiology, cardiology, hematology, psychology and rehabilitation. ''Cerebrovascular Diseases'' is an international forum which meets the growing need for sophisticated, up-to-date scientific information on clinical data, diagnostic testing, and therapeutic issues, dealing with all aspects of stroke and cerebrovascular diseases. It contains original contributions, reviews of selected topics and clinical investigative studies, recent meeting reports and work-in-progress as well as discussions on controversial issues. All aspects related to clinical advances are considered, while purely experimental work appears if directly relevant to clinical issues.
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