{"title":"纳米材料增强牙科:临床视角。","authors":"Selvam Manoj, Radhakrishnan Sreena, Rajkumar Divya, Starlin Ebinesh, Shenbagaraman Akshaya, Srikumar Sugantha Angel, Arputharaj Joseph Nathanael","doi":"10.1021/acsbiomaterials.5c00350","DOIUrl":null,"url":null,"abstract":"<p><p>Dental health is a critical component of the overall well-being, yet billions of people worldwide suffer from various dental diseases, according to the World Health Organization. The conventional diagnosis and treatment methods possess limitations in mechanical properties, biocompatibility, and several others. Nanotechnology presents a promising solution for addressing these challenges by enabling the development of novel materials with enhanced properties, currently regarded as \"nanodentistry\". By employing the unique properties of nanomaterials in oral diseases, an effective, infection-less dental treatment can be envisioned. Although nanomaterials have great promise in dentistry, the existing literature often lacks a comprehensive overview of their clinical applications across various oral diseases. This review explores current nanodental applications, discusses commercial products, examines translational challenges, and outlines future prospects for integrating nanomaterials across various dental specialties.</p>","PeriodicalId":8,"journal":{"name":"ACS Biomaterials Science & Engineering","volume":" ","pages":""},"PeriodicalIF":5.4000,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nanomaterial-Enhanced Dentistry: A Clinical Perspective.\",\"authors\":\"Selvam Manoj, Radhakrishnan Sreena, Rajkumar Divya, Starlin Ebinesh, Shenbagaraman Akshaya, Srikumar Sugantha Angel, Arputharaj Joseph Nathanael\",\"doi\":\"10.1021/acsbiomaterials.5c00350\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Dental health is a critical component of the overall well-being, yet billions of people worldwide suffer from various dental diseases, according to the World Health Organization. The conventional diagnosis and treatment methods possess limitations in mechanical properties, biocompatibility, and several others. Nanotechnology presents a promising solution for addressing these challenges by enabling the development of novel materials with enhanced properties, currently regarded as \\\"nanodentistry\\\". By employing the unique properties of nanomaterials in oral diseases, an effective, infection-less dental treatment can be envisioned. Although nanomaterials have great promise in dentistry, the existing literature often lacks a comprehensive overview of their clinical applications across various oral diseases. This review explores current nanodental applications, discusses commercial products, examines translational challenges, and outlines future prospects for integrating nanomaterials across various dental specialties.</p>\",\"PeriodicalId\":8,\"journal\":{\"name\":\"ACS Biomaterials Science & Engineering\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":5.4000,\"publicationDate\":\"2025-07-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Biomaterials Science & Engineering\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1021/acsbiomaterials.5c00350\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Biomaterials Science & Engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1021/acsbiomaterials.5c00350","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
Nanomaterial-Enhanced Dentistry: A Clinical Perspective.
Dental health is a critical component of the overall well-being, yet billions of people worldwide suffer from various dental diseases, according to the World Health Organization. The conventional diagnosis and treatment methods possess limitations in mechanical properties, biocompatibility, and several others. Nanotechnology presents a promising solution for addressing these challenges by enabling the development of novel materials with enhanced properties, currently regarded as "nanodentistry". By employing the unique properties of nanomaterials in oral diseases, an effective, infection-less dental treatment can be envisioned. Although nanomaterials have great promise in dentistry, the existing literature often lacks a comprehensive overview of their clinical applications across various oral diseases. This review explores current nanodental applications, discusses commercial products, examines translational challenges, and outlines future prospects for integrating nanomaterials across various dental specialties.
期刊介绍:
ACS Biomaterials Science & Engineering is the leading journal in the field of biomaterials, serving as an international forum for publishing cutting-edge research and innovative ideas on a broad range of topics:
Applications and Health – implantable tissues and devices, prosthesis, health risks, toxicology
Bio-interactions and Bio-compatibility – material-biology interactions, chemical/morphological/structural communication, mechanobiology, signaling and biological responses, immuno-engineering, calcification, coatings, corrosion and degradation of biomaterials and devices, biophysical regulation of cell functions
Characterization, Synthesis, and Modification – new biomaterials, bioinspired and biomimetic approaches to biomaterials, exploiting structural hierarchy and architectural control, combinatorial strategies for biomaterials discovery, genetic biomaterials design, synthetic biology, new composite systems, bionics, polymer synthesis
Controlled Release and Delivery Systems – biomaterial-based drug and gene delivery, bio-responsive delivery of regulatory molecules, pharmaceutical engineering
Healthcare Advances – clinical translation, regulatory issues, patient safety, emerging trends
Imaging and Diagnostics – imaging agents and probes, theranostics, biosensors, monitoring
Manufacturing and Technology – 3D printing, inks, organ-on-a-chip, bioreactor/perfusion systems, microdevices, BioMEMS, optics and electronics interfaces with biomaterials, systems integration
Modeling and Informatics Tools – scaling methods to guide biomaterial design, predictive algorithms for structure-function, biomechanics, integrating bioinformatics with biomaterials discovery, metabolomics in the context of biomaterials
Tissue Engineering and Regenerative Medicine – basic and applied studies, cell therapies, scaffolds, vascularization, bioartificial organs, transplantation and functionality, cellular agriculture