{"title":"利用基于ml的代理模型综合预测基于支柱的陀螺晶格结构的相对模量","authors":"Naufal Muhammad Judawisastra, Satrio Wicaksono, Yohanes Bimo Dwianto, Andi Isra Mahyuddin, Tatacipta Dirgantara, Lavi Rizki Zuhal","doi":"10.1002/jbm.b.35613","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Due to its porous structure, tunable properties, and nearly isotropic characteristics, the Gyroid Lattice Structure (GLS) is widely utilized in orthopedic implant applications. To effectively reduce stress shielding and enhance implant longevity, it is essential to accurately predict the GLS's elastic moduli across a broad range of relative densities for various material selections. This study conducted a comprehensive finite element analysis of strut-based GLS models, considering unit cell arrangements, a wider range of relative densities, and variations in lattice orientations to predict its relative elastic moduli. GLS models with relative densities of 10%, 30%, 50%, and 75% were experimentally tested and numerically analyzed to capture properties across a broader density range. The well-known Gibson-Ashby model and a machine learning (ML)-based surrogate model employing Gaussian Process Regression were developed to extend predictions across the full-density spectrum. The results showed that different relative densities required varying numbers of unit cells to achieve elastic modulus convergence. The improved Gibson-Ashby model provided closer predictions to experiments over a wider density range but struggled to fully capture behavior at high relative densities near bulk material properties. In contrast, the ML-based surrogate model accurately predicts elastic moduli across the entire relative density range. Compared to experimental results, this approach demonstrates greater accuracy in predicting the elastic modulus of GLS, with reduced error compared to other methods. These findings are particularly valuable for optimizing implant and scaffold designs, as accurate modulus predictions contribute to improved performance and longevity, helping to mitigate the stress-shielding effect.</p>\n </div>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comprehensive Prediction of the Relative Modulus of Strut-Based Gyroid Lattice Structures Employing an ML-Based Surrogate Model\",\"authors\":\"Naufal Muhammad Judawisastra, Satrio Wicaksono, Yohanes Bimo Dwianto, Andi Isra Mahyuddin, Tatacipta Dirgantara, Lavi Rizki Zuhal\",\"doi\":\"10.1002/jbm.b.35613\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p>Due to its porous structure, tunable properties, and nearly isotropic characteristics, the Gyroid Lattice Structure (GLS) is widely utilized in orthopedic implant applications. To effectively reduce stress shielding and enhance implant longevity, it is essential to accurately predict the GLS's elastic moduli across a broad range of relative densities for various material selections. This study conducted a comprehensive finite element analysis of strut-based GLS models, considering unit cell arrangements, a wider range of relative densities, and variations in lattice orientations to predict its relative elastic moduli. GLS models with relative densities of 10%, 30%, 50%, and 75% were experimentally tested and numerically analyzed to capture properties across a broader density range. The well-known Gibson-Ashby model and a machine learning (ML)-based surrogate model employing Gaussian Process Regression were developed to extend predictions across the full-density spectrum. The results showed that different relative densities required varying numbers of unit cells to achieve elastic modulus convergence. The improved Gibson-Ashby model provided closer predictions to experiments over a wider density range but struggled to fully capture behavior at high relative densities near bulk material properties. In contrast, the ML-based surrogate model accurately predicts elastic moduli across the entire relative density range. Compared to experimental results, this approach demonstrates greater accuracy in predicting the elastic modulus of GLS, with reduced error compared to other methods. These findings are particularly valuable for optimizing implant and scaffold designs, as accurate modulus predictions contribute to improved performance and longevity, helping to mitigate the stress-shielding effect.</p>\\n </div>\",\"PeriodicalId\":15269,\"journal\":{\"name\":\"Journal of biomedical materials research. Part B, Applied biomaterials\",\"volume\":\"113 8\",\"pages\":\"\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2025-07-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of biomedical materials research. Part B, Applied biomaterials\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jbm.b.35613\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomedical materials research. Part B, Applied biomaterials","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jbm.b.35613","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Comprehensive Prediction of the Relative Modulus of Strut-Based Gyroid Lattice Structures Employing an ML-Based Surrogate Model
Due to its porous structure, tunable properties, and nearly isotropic characteristics, the Gyroid Lattice Structure (GLS) is widely utilized in orthopedic implant applications. To effectively reduce stress shielding and enhance implant longevity, it is essential to accurately predict the GLS's elastic moduli across a broad range of relative densities for various material selections. This study conducted a comprehensive finite element analysis of strut-based GLS models, considering unit cell arrangements, a wider range of relative densities, and variations in lattice orientations to predict its relative elastic moduli. GLS models with relative densities of 10%, 30%, 50%, and 75% were experimentally tested and numerically analyzed to capture properties across a broader density range. The well-known Gibson-Ashby model and a machine learning (ML)-based surrogate model employing Gaussian Process Regression were developed to extend predictions across the full-density spectrum. The results showed that different relative densities required varying numbers of unit cells to achieve elastic modulus convergence. The improved Gibson-Ashby model provided closer predictions to experiments over a wider density range but struggled to fully capture behavior at high relative densities near bulk material properties. In contrast, the ML-based surrogate model accurately predicts elastic moduli across the entire relative density range. Compared to experimental results, this approach demonstrates greater accuracy in predicting the elastic modulus of GLS, with reduced error compared to other methods. These findings are particularly valuable for optimizing implant and scaffold designs, as accurate modulus predictions contribute to improved performance and longevity, helping to mitigate the stress-shielding effect.
期刊介绍:
Journal of Biomedical Materials Research – Part B: Applied Biomaterials is a highly interdisciplinary peer-reviewed journal serving the needs of biomaterials professionals who design, develop, produce and apply biomaterials and medical devices. It has the common focus of biomaterials applied to the human body and covers all disciplines where medical devices are used. Papers are published on biomaterials related to medical device development and manufacture, degradation in the body, nano- and biomimetic- biomaterials interactions, mechanics of biomaterials, implant retrieval and analysis, tissue-biomaterial surface interactions, wound healing, infection, drug delivery, standards and regulation of devices, animal and pre-clinical studies of biomaterials and medical devices, and tissue-biopolymer-material combination products. Manuscripts are published in one of six formats:
• original research reports
• short research and development reports
• scientific reviews
• current concepts articles
• special reports
• editorials
Journal of Biomedical Materials Research – Part B: Applied Biomaterials is an official journal of the Society for Biomaterials, Japanese Society for Biomaterials, the Australasian Society for Biomaterials, and the Korean Society for Biomaterials. Manuscripts from all countries are invited but must be in English. Authors are not required to be members of the affiliated Societies, but members of these societies are encouraged to submit their work to the journal for consideration.