Yanrong Tian, Donghui Cao, Xusheng Li, Yan Ma, Xiao Zhang, Xi Zhu, Wenbo Gu, Yu Yang, Pengcheng Mao, Haifeng Yuan
{"title":"L5-S1椎间孔狭窄患者经皮内镜下腰椎间盘切除术后活动功能相关因素分析。","authors":"Yanrong Tian, Donghui Cao, Xusheng Li, Yan Ma, Xiao Zhang, Xi Zhu, Wenbo Gu, Yu Yang, Pengcheng Mao, Haifeng Yuan","doi":"10.1016/j.wneu.2025.124289","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the factors influencing postoperative ambulatory function in patients with L5-S1 foraminal stenosis who underwent percutaneous endoscopic lumbar discectomy (PELD).</p><p><strong>Methods: </strong>This retrospective study was conducted on the clinical data of 146 patients with L5-S1 foraminal stenosis who underwent percutaneous endoscopic lumbar discectomy (PELD) at the General Hospital of Ningxia Medical University between January 2023 and February 2024. The 6-minute walk distance (6MWD) test evaluated ambulatory function at 3 months postoperatively. Demographic characteristics, clinical features, comorbidities, and surgery-related parameters were collected. Univariate analysis and Pearson correlation tests were performed using the 6MWD at 3 months as the dependent variable. Variables with statistical significance (P < 0.05) were then entered into a multivariate linear regression analysis to identify independent predictors and establish a predictive model.</p><p><strong>Results: </strong>A total of 146 patients with L5-S1 foraminal stenosis were retrospectively analyzed. Univariate analysis showed that educational level had a significant impact on the 6-minute walk distance (6MWD) at 3 months postoperatively (P < 0.001). Pearson correlation analysis revealed that postoperative 6MWD was significantly correlated with age, body weight, lower limb pain visual analog scale (VAS) score, preoperative 6MWD (assessed one day before surgery), and preoperative low back pain VAS score (P < 0.05). Multivariate linear regression analysis identified preoperative 6MWD, age, and body weight as independent predictors of postoperative 6MWD (P < 0.05). The predictive equation derived from the regression model was as follows: Postoperative 6MWD at 3 months=163.498+(0.885×Preoperative 6MWD)-(0.515×Age)-(0.775×Body Weight) CONCLUSION: Multiple factors influence ambulatory function following percutaneous endoscopic lumbar discectomy (PELD) in patients with L5-S1 foraminal stenosis. A better preoperative 6-minute walk distance (6MWD), younger age, and lower body weight were associated with improved postoperative 6MWD outcomes.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124289"},"PeriodicalIF":2.1000,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysis of Factors Associated with Ambulatory Function Following Percutaneous Endoscopic Lumbar Discectomy in Patients with L5-S1 Foraminal Stenosis.\",\"authors\":\"Yanrong Tian, Donghui Cao, Xusheng Li, Yan Ma, Xiao Zhang, Xi Zhu, Wenbo Gu, Yu Yang, Pengcheng Mao, Haifeng Yuan\",\"doi\":\"10.1016/j.wneu.2025.124289\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To investigate the factors influencing postoperative ambulatory function in patients with L5-S1 foraminal stenosis who underwent percutaneous endoscopic lumbar discectomy (PELD).</p><p><strong>Methods: </strong>This retrospective study was conducted on the clinical data of 146 patients with L5-S1 foraminal stenosis who underwent percutaneous endoscopic lumbar discectomy (PELD) at the General Hospital of Ningxia Medical University between January 2023 and February 2024. The 6-minute walk distance (6MWD) test evaluated ambulatory function at 3 months postoperatively. Demographic characteristics, clinical features, comorbidities, and surgery-related parameters were collected. Univariate analysis and Pearson correlation tests were performed using the 6MWD at 3 months as the dependent variable. Variables with statistical significance (P < 0.05) were then entered into a multivariate linear regression analysis to identify independent predictors and establish a predictive model.</p><p><strong>Results: </strong>A total of 146 patients with L5-S1 foraminal stenosis were retrospectively analyzed. Univariate analysis showed that educational level had a significant impact on the 6-minute walk distance (6MWD) at 3 months postoperatively (P < 0.001). Pearson correlation analysis revealed that postoperative 6MWD was significantly correlated with age, body weight, lower limb pain visual analog scale (VAS) score, preoperative 6MWD (assessed one day before surgery), and preoperative low back pain VAS score (P < 0.05). Multivariate linear regression analysis identified preoperative 6MWD, age, and body weight as independent predictors of postoperative 6MWD (P < 0.05). The predictive equation derived from the regression model was as follows: Postoperative 6MWD at 3 months=163.498+(0.885×Preoperative 6MWD)-(0.515×Age)-(0.775×Body Weight) CONCLUSION: Multiple factors influence ambulatory function following percutaneous endoscopic lumbar discectomy (PELD) in patients with L5-S1 foraminal stenosis. A better preoperative 6-minute walk distance (6MWD), younger age, and lower body weight were associated with improved postoperative 6MWD outcomes.</p>\",\"PeriodicalId\":23906,\"journal\":{\"name\":\"World neurosurgery\",\"volume\":\" \",\"pages\":\"124289\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-07-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World neurosurgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.wneu.2025.124289\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World neurosurgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.wneu.2025.124289","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Analysis of Factors Associated with Ambulatory Function Following Percutaneous Endoscopic Lumbar Discectomy in Patients with L5-S1 Foraminal Stenosis.
Purpose: To investigate the factors influencing postoperative ambulatory function in patients with L5-S1 foraminal stenosis who underwent percutaneous endoscopic lumbar discectomy (PELD).
Methods: This retrospective study was conducted on the clinical data of 146 patients with L5-S1 foraminal stenosis who underwent percutaneous endoscopic lumbar discectomy (PELD) at the General Hospital of Ningxia Medical University between January 2023 and February 2024. The 6-minute walk distance (6MWD) test evaluated ambulatory function at 3 months postoperatively. Demographic characteristics, clinical features, comorbidities, and surgery-related parameters were collected. Univariate analysis and Pearson correlation tests were performed using the 6MWD at 3 months as the dependent variable. Variables with statistical significance (P < 0.05) were then entered into a multivariate linear regression analysis to identify independent predictors and establish a predictive model.
Results: A total of 146 patients with L5-S1 foraminal stenosis were retrospectively analyzed. Univariate analysis showed that educational level had a significant impact on the 6-minute walk distance (6MWD) at 3 months postoperatively (P < 0.001). Pearson correlation analysis revealed that postoperative 6MWD was significantly correlated with age, body weight, lower limb pain visual analog scale (VAS) score, preoperative 6MWD (assessed one day before surgery), and preoperative low back pain VAS score (P < 0.05). Multivariate linear regression analysis identified preoperative 6MWD, age, and body weight as independent predictors of postoperative 6MWD (P < 0.05). The predictive equation derived from the regression model was as follows: Postoperative 6MWD at 3 months=163.498+(0.885×Preoperative 6MWD)-(0.515×Age)-(0.775×Body Weight) CONCLUSION: Multiple factors influence ambulatory function following percutaneous endoscopic lumbar discectomy (PELD) in patients with L5-S1 foraminal stenosis. A better preoperative 6-minute walk distance (6MWD), younger age, and lower body weight were associated with improved postoperative 6MWD outcomes.
期刊介绍：
World Neurosurgery has an open access mirror journal World Neurosurgery: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
The journal''s mission is to:
-To provide a first-class international forum and a 2-way conduit for dialogue that is relevant to neurosurgeons and providers who care for neurosurgery patients. The categories of the exchanged information include clinical and basic science, as well as global information that provide social, political, educational, economic, cultural or societal insights and knowledge that are of significance and relevance to worldwide neurosurgery patient care.
-To act as a primary intellectual catalyst for the stimulation of creativity, the creation of new knowledge, and the enhancement of quality neurosurgical care worldwide.
-To provide a forum for communication that enriches the lives of all neurosurgeons and their colleagues; and, in so doing, enriches the lives of their patients.
Topics to be addressed in World Neurosurgery include: EDUCATION, ECONOMICS, RESEARCH, POLITICS, HISTORY, CULTURE, CLINICAL SCIENCE, LABORATORY SCIENCE, TECHNOLOGY, OPERATIVE TECHNIQUES, CLINICAL IMAGES, VIDEOS
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