情绪压力和心血管健康:对神经退行性疾病进展的影响。

4区 医学 Q3 Neuroscience
Progress in brain research Pub Date : 2025-01-01 Epub Date: 2025-04-23 DOI:10.1016/bs.pbr.2025.04.004
Mostafa K Abd El-Aziz, Al-Hassan Soliman Wadan, Abdelrahman T I Albahttiti, Nasrollah Moradikor
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引用次数: 0

摘要

压力是人们生活中不可避免的一部分,被认为对健康有严重影响,特别是在心血管疾病和神经退行性疾病的情况下。本章旨在揭示情绪压力、心血管健康和神经退行性疾病进展之间的联系。因此,慢性应激被认为是心血管疾病的一个重要原因,主要是因为它对下丘脑-垂体-肾上腺(HPA)轴和交感神经(SNS)的影响,其中神经退行性疾病系统如阿尔茨海默病(ALS)的炎症机制和疾病,血管如帕金森病的功能。工作机制也建立了CVD和NDD之间的串扰,表明它们具有遗传、分子和系统关联。了解这些途径对设计干预措施至关重要,这些干预措施将有助于预防或减轻压力对健康的影响,从而加强对患者的护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Emotional stress and cardiovascular health: Impacts on neurodegenerative disease progression.

Stress is an inevitable part of people's lives and is considered to have a severe impact on health, especially in the case of cardiovascular diseases and neurodegenerative diseases. This chapter aims to reveal the links between emotional stress, cardiovascular health, and neurodegenerative disease progression. Chronic stress is therefore recognized as a significant cause of cardiovascular diseases mainly because of the effects it has on the hypothalamic-pituitary-adrenal (HPA) axis and the (SNS) sympathetic which neurodegenerative nervous are diseases system such (as ALS) through inflammation of Alzheimer's mechanisms and disease, vascular such as Parkinson's functions. The mechanisms of work also establish the crosstalk between CVD and NDD, demonstrating that they share genetic, molecular, and systemic associations. It is essential to know these pathways to design interventions that will help prevent or lessen the effects of stress on health and thus enhance patient care.

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来源期刊
Progress in brain research
Progress in brain research 医学-神经科学
CiteScore
5.20
自引率
0.00%
发文量
174
审稿时长
6-12 weeks
期刊介绍: Progress in Brain Research is the most acclaimed and accomplished series in neuroscience. The serial is well-established as an extensive documentation of contemporary advances in the field. The volumes contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry and the behavioral sciences.
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