Clemens Roitzsch, Franziska Beyer, Klaus-Dieter Schaser, Roman Riedel, Marcel Mäder, Anne Postler
{"title":"揭示隐藏的风险：老年人股骨近端骨折的90天死亡率和并发症。","authors":"Clemens Roitzsch, Franziska Beyer, Klaus-Dieter Schaser, Roman Riedel, Marcel Mäder, Anne Postler","doi":"10.1007/s40520-025-03134-0","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Proximal femur fractures (PFF) are the most common fracture type worldwide, particularly in geriatric patients. Despite advancement in treatment, mortality rates in this patient group remain high.</p><p><strong>Aims: </strong>The aim of this study was to analyze potential factors, influencing the 90-day mortality rate and complication rate after PFF surgery in a tertiary care hospital.</p><p><strong>Methods: </strong>Between 2019 and 2022, all patients aged 65 and older with PFF and a positive screening as a geriatric patient were included in this prospective, single-center study. Data collected included gender, age, BMI, fracture type, type and timing of surgery, comorbidities, medication, mobilization and blood loss as well as complications and 90-day mortality.</p><p><strong>Results: </strong>Out of 1217 analyzed geriatric patients, 61% underwent surgery within 24 h. The complication rate was 21.7% with 3% surgical and 20.2% non-surgical complications. Median age was 87 years and 68% were female, while mean Charlson Comorbidity Index was 2.6 points and 84% had ASA 3 or 4. 240 patients (19.7%) died within 90 days after surgery. Higher mortality rates were associated with male gender (OR 1.341), higher age (OR 1.093), lower BMI (OR 0.946), higher Charlson Comorbidity Index (OR 1.202), non-surgical complications (OR 2.541) and if mobilization was impossible (OR 10.013). A delay of surgery beyond 24 h after admission was associated with the development of wound infections (p = 0.022) and internal medicine-related complications (p = 0.002).</p><p><strong>Discussion: </strong>While no correlation was found between surgery timing and 90 days mortality, delays in surgery were associated with adverse effects, including wound infections and internal medicine complications.</p><p><strong>Conclusion: </strong>The mortality rates of patients suffering from PFF maintain high and are mainly influenced by non-modifiable patient-related factors.</p><p><strong>Clinical trials registration: </strong>German Registry for Clinical Trials, ID: DRKS00034048, date of registration: 10.02.2025. Retrospectively registered.</p>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":"220"},"PeriodicalIF":3.4000,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276096/pdf/","citationCount":"0","resultStr":"{\"title\":\"Unveiling the hidden risks: 90-day mortality and complications in older adults with proximal femur fractures.\",\"authors\":\"Clemens Roitzsch, Franziska Beyer, Klaus-Dieter Schaser, Roman Riedel, Marcel Mäder, Anne Postler\",\"doi\":\"10.1007/s40520-025-03134-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Proximal femur fractures (PFF) are the most common fracture type worldwide, particularly in geriatric patients. Despite advancement in treatment, mortality rates in this patient group remain high.</p><p><strong>Aims: </strong>The aim of this study was to analyze potential factors, influencing the 90-day mortality rate and complication rate after PFF surgery in a tertiary care hospital.</p><p><strong>Methods: </strong>Between 2019 and 2022, all patients aged 65 and older with PFF and a positive screening as a geriatric patient were included in this prospective, single-center study. Data collected included gender, age, BMI, fracture type, type and timing of surgery, comorbidities, medication, mobilization and blood loss as well as complications and 90-day mortality.</p><p><strong>Results: </strong>Out of 1217 analyzed geriatric patients, 61% underwent surgery within 24 h. The complication rate was 21.7% with 3% surgical and 20.2% non-surgical complications. Median age was 87 years and 68% were female, while mean Charlson Comorbidity Index was 2.6 points and 84% had ASA 3 or 4. 240 patients (19.7%) died within 90 days after surgery. Higher mortality rates were associated with male gender (OR 1.341), higher age (OR 1.093), lower BMI (OR 0.946), higher Charlson Comorbidity Index (OR 1.202), non-surgical complications (OR 2.541) and if mobilization was impossible (OR 10.013). A delay of surgery beyond 24 h after admission was associated with the development of wound infections (p = 0.022) and internal medicine-related complications (p = 0.002).</p><p><strong>Discussion: </strong>While no correlation was found between surgery timing and 90 days mortality, delays in surgery were associated with adverse effects, including wound infections and internal medicine complications.</p><p><strong>Conclusion: </strong>The mortality rates of patients suffering from PFF maintain high and are mainly influenced by non-modifiable patient-related factors.</p><p><strong>Clinical trials registration: </strong>German Registry for Clinical Trials, ID: DRKS00034048, date of registration: 10.02.2025. Retrospectively registered.</p>\",\"PeriodicalId\":7720,\"journal\":{\"name\":\"Aging Clinical and Experimental Research\",\"volume\":\"37 1\",\"pages\":\"220\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2025-07-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276096/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Aging Clinical and Experimental Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s40520-025-03134-0\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GERIATRICS & GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aging Clinical and Experimental Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s40520-025-03134-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
Unveiling the hidden risks: 90-day mortality and complications in older adults with proximal femur fractures.
Background: Proximal femur fractures (PFF) are the most common fracture type worldwide, particularly in geriatric patients. Despite advancement in treatment, mortality rates in this patient group remain high.
Aims: The aim of this study was to analyze potential factors, influencing the 90-day mortality rate and complication rate after PFF surgery in a tertiary care hospital.
Methods: Between 2019 and 2022, all patients aged 65 and older with PFF and a positive screening as a geriatric patient were included in this prospective, single-center study. Data collected included gender, age, BMI, fracture type, type and timing of surgery, comorbidities, medication, mobilization and blood loss as well as complications and 90-day mortality.
Results: Out of 1217 analyzed geriatric patients, 61% underwent surgery within 24 h. The complication rate was 21.7% with 3% surgical and 20.2% non-surgical complications. Median age was 87 years and 68% were female, while mean Charlson Comorbidity Index was 2.6 points and 84% had ASA 3 or 4. 240 patients (19.7%) died within 90 days after surgery. Higher mortality rates were associated with male gender (OR 1.341), higher age (OR 1.093), lower BMI (OR 0.946), higher Charlson Comorbidity Index (OR 1.202), non-surgical complications (OR 2.541) and if mobilization was impossible (OR 10.013). A delay of surgery beyond 24 h after admission was associated with the development of wound infections (p = 0.022) and internal medicine-related complications (p = 0.002).
Discussion: While no correlation was found between surgery timing and 90 days mortality, delays in surgery were associated with adverse effects, including wound infections and internal medicine complications.
Conclusion: The mortality rates of patients suffering from PFF maintain high and are mainly influenced by non-modifiable patient-related factors.
Clinical trials registration: German Registry for Clinical Trials, ID: DRKS00034048, date of registration: 10.02.2025. Retrospectively registered.
期刊介绍：
Aging clinical and experimental research offers a multidisciplinary forum on the progressing field of gerontology and geriatrics. The areas covered by the journal include: biogerontology, neurosciences, epidemiology, clinical gerontology and geriatric assessment, social, economical and behavioral gerontology. “Aging clinical and experimental research” appears bimonthly and publishes review articles, original papers and case reports.
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