cd10 + cd23 +毛细胞白血病伴白细胞增多1例。病例报告及文献复习。

Experimental oncology Pub Date : 2025-07-11 DOI:10.15407/exp-oncology.2025.01.091

I Skrypnyk, G Maslova, T Lymanets, I Gusachenko, G Yeroshenko

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引用次数: 0

摘要

本文报道一例罕见的毛细胞白血病伴CD10+CD23+表达和白细胞增多。毛细胞白血病的关键标志物是BRAF V600E突变的存在，而与白细胞计数和非典型异常CD10+或CD23+表达无关。本文的临床病例报告对了解毛细胞白血病的生物学具有重要意义，并强调了分子基因检测在非典型形态表型疾病表现中的作用。

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RARE CASE OF CD10+CD23+ HAIRY CELL LEUKEMIA WITH LEUKOCYTOSIS. CASE REPORT AND LITERATURE REVIEW.

A rare case of hairy cell leukemia with CD10+CD23+ expression and leukocytosis is described. The key point marker for hairy cell leukemia is the presence of the BRAF V600E mutation regardless of the leukocyte count and atypical aberrant CD10+ or CD23+ expression. The presented clinical case report is important for understanding the biology of hairy cell leukemia and emphasizes the role of molecular genetic testing in atypical morpho-phenotyping disease presentation.

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Experimental oncology

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