{"title":"血管结垢:增生和挤压之间的一种谨慎的平衡行为。","authors":"Alexandra Hiestand, Stefano Di Talia","doi":"10.1016/j.cels.2025.101343","DOIUrl":null,"url":null,"abstract":"<p><p>How do vascular tissues grow with the rest of the developing organism postnatally? In this issue of Cell Systems, Pi et al. combine modeling with molecular biology to uncover how cell behaviors scale growth. Notably, they discover how proliferation and extrusion regulate endothelial cell number in dorsal aorta development.</p>","PeriodicalId":93929,"journal":{"name":"Cell systems","volume":"16 7","pages":"101343"},"PeriodicalIF":7.7000,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Vascular scaling: A careful balancing act between proliferation and extrusion.\",\"authors\":\"Alexandra Hiestand, Stefano Di Talia\",\"doi\":\"10.1016/j.cels.2025.101343\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>How do vascular tissues grow with the rest of the developing organism postnatally? In this issue of Cell Systems, Pi et al. combine modeling with molecular biology to uncover how cell behaviors scale growth. Notably, they discover how proliferation and extrusion regulate endothelial cell number in dorsal aorta development.</p>\",\"PeriodicalId\":93929,\"journal\":{\"name\":\"Cell systems\",\"volume\":\"16 7\",\"pages\":\"101343\"},\"PeriodicalIF\":7.7000,\"publicationDate\":\"2025-07-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.cels.2025.101343\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.cels.2025.101343","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Vascular scaling: A careful balancing act between proliferation and extrusion.
How do vascular tissues grow with the rest of the developing organism postnatally? In this issue of Cell Systems, Pi et al. combine modeling with molecular biology to uncover how cell behaviors scale growth. Notably, they discover how proliferation and extrusion regulate endothelial cell number in dorsal aorta development.