Yuanli Lei, Aqsa Asharf, Jessica Amos, Mohamad Khawandanah, Anand Annan, James Battiste, Michel Torbey, Taha Al-Juhaishi, Nidhiben Anadani
{"title":"诊断过程：原发性中枢神经系统淋巴瘤（脑淋巴瘤）表现为快速进行性痴呆。","authors":"Yuanli Lei, Aqsa Asharf, Jessica Amos, Mohamad Khawandanah, Anand Annan, James Battiste, Michel Torbey, Taha Al-Juhaishi, Nidhiben Anadani","doi":"10.1155/crh/8819799","DOIUrl":null,"url":null,"abstract":"<p><p>Primary central nervous system lymphoma (PCNSL) is a rare brain cancer that sometimes presented as rapidly progressive dementia. Diagnosing PCNSL presenting with rapidly progressive neurocognitive symptoms can be challenging, especially when the patient was previously treated with immunosuppressants for suspected autoimmune processes. We present a case where PCNLS was eventually and successfully treated 18 months after neurological symptoms started.</p>","PeriodicalId":46307,"journal":{"name":"Case Reports in Hematology","volume":"2025 ","pages":"8819799"},"PeriodicalIF":0.7000,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267979/pdf/","citationCount":"0","resultStr":"{\"title\":\"Diagnostic Odyssey: Primary CNS Lymphoma (Lymphoma Cerebri) Presenting as Rapidly Progressive Dementia.\",\"authors\":\"Yuanli Lei, Aqsa Asharf, Jessica Amos, Mohamad Khawandanah, Anand Annan, James Battiste, Michel Torbey, Taha Al-Juhaishi, Nidhiben Anadani\",\"doi\":\"10.1155/crh/8819799\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Primary central nervous system lymphoma (PCNSL) is a rare brain cancer that sometimes presented as rapidly progressive dementia. Diagnosing PCNSL presenting with rapidly progressive neurocognitive symptoms can be challenging, especially when the patient was previously treated with immunosuppressants for suspected autoimmune processes. We present a case where PCNLS was eventually and successfully treated 18 months after neurological symptoms started.</p>\",\"PeriodicalId\":46307,\"journal\":{\"name\":\"Case Reports in Hematology\",\"volume\":\"2025 \",\"pages\":\"8819799\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-07-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267979/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Hematology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/crh/8819799\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"HEMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Hematology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crh/8819799","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"HEMATOLOGY","Score":null,"Total":0}
Primary central nervous system lymphoma (PCNSL) is a rare brain cancer that sometimes presented as rapidly progressive dementia. Diagnosing PCNSL presenting with rapidly progressive neurocognitive symptoms can be challenging, especially when the patient was previously treated with immunosuppressants for suspected autoimmune processes. We present a case where PCNLS was eventually and successfully treated 18 months after neurological symptoms started.
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