[支气管镜下肺减容治疗严重慢性阻塞性肺疾病]。

Q4 Medicine
Takahiro Nakajima, Takashi Inoue, Hiroaki Okutomi, Akihiro Takemasa, Yasuo Shimizu, Sumiko Maeda, Seiji Niho, Masayuki Chida
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引用次数: 0

摘要

支气管镜下肺减容术(BLVR)已有10多年的历史,在全球已有超过25,000例病例。在全球慢性阻塞性肺疾病倡议(GOLD)指南中,它被推荐为A级证据。然而,在日本,直到2023年12月才被批准纳入保险范围,而且在指定的机构才开始治疗。BLVR作为一种治疗选择,弥补了严重慢性阻塞性肺疾病(COPD)病例的内科和外科治疗之间的差距。在日本,同质性肺气肿更为普遍,BLVR为接受最大药物治疗后仍出现呼吸困难的严重COPD患者提供了一种有希望的新治疗选择。BLVR的成功取决于基于适当评估的正确患者选择,包括使用Chartis系统评估侧支通气。接受BLVR的患者可以预期FEV1.0和6分钟步行距离的改善,最终导致更高的生存率。希望BLVR能够帮助重度COPD患者摆脱COPD的恶性循环,维持患者的生活质量,最终有助于降低COPD相关死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Bronchoscopic Lung Volume Reduction for Severe Chronic Obstructive Lung Disease].

Bronchoscopic lung volume reduction( BLVR) has a history of over 10 years and has been performed in more than 25,000 cases worldwide. It is recommended with an evidence A rating in the Global Initiative for Chronic Obstructive Lung Disease( GOLD) guidelines. However, in Japan, it was only approved for insurance coverage in December 2023, and treatment has just begun at designated facilities. BLVR serves as a treatment option that bridges the gap between medical and surgical treatments for severe chronic obstructive pulmonary disease (COPD) cases. In Japan, where homogeneous emphysema is more prevalent, BLVR offers a promising new treatment option for severe COPD patients who continue to experience dyspnea despite receiving maximal medical therapy. The success of BLVR depends on proper patient selection based on appropriate evaluation, including the assessment of collateral ventilation using the Chartis system. Patients undergoing BLVR can expect improvements in FEV1.0 and the six-minute walk distance, ultimately leading to better survival rates. It is hoped that BLVR will help severe COPD patients break free from the negative spiral of COPD, maintain their quality of life, and ultimately contribute to reducing COPD-related mortality.

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