Yu Song, Xu Zhang, Jingyun Li, Luo Zhang, Yuan Zhang
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引用次数: 0
摘要
简介：变应性鼻炎（Allergic rhinitis， AR）是一种常见的由免疫球蛋白E （Immunoglobulin E, IgE）介导的鼻黏膜非感染性慢性炎症性疾病。目前，AR的诊断主要依靠典型的过敏史、临床症状体征、皮肤点刺试验、鼻腔激发试验、血清特异性IgE检测。鼻分泌物细胞学作为一种直接反映鼻腔炎症状态的方法，在AR的诊断和治疗中也具有重要的作用。涉及领域：本文根据系统选择的PubMed数据库文章，对鼻细胞学在AR的诊断和治疗中的作用进行了总结和讨论，旨在推进该方法及其临床应用。专家意见：鼻细胞学在彻底改变AR的诊断和治疗方面具有巨大的潜力。通过标准化、验证研究和新技术的整合来解决当前的挑战和局限性，将为其广泛采用铺平道路，并最终为精准医疗做出贡献。
The role of nasal cytology in the diagnosis and treatment of Allergic rhinitis.
Introduction: Allergic rhinitis (AR) is a common noninfectious chronic inflammatory disease of the nasal mucosa mediated by Immunoglobulin E (IgE). Currently, the diagnosis of AR mainly relies on a typical history of allergies, clinical symptoms and signs, skin prick tests, nasal provocation tests, and serum specific IgE detection. Nasal secretion cytology, as a method that directly reflects the inflammatory status in the nasal cavity, also plays a significant role in the diagnosis and treatment of AR.
Areas covered: This review summarizes and discusses the role of nasal cytology in the diagnosis and treatment of AR, based on systematically selected articles from the PubMed database, with the aim of advancing this method and its clinical application.
Expert opinion: Nasal cytology holds significant potential in revolutionizing the diagnosis and treatment of AR. Addressing the current challenges and limitations through standardization, validation studies, and integration of new technologies will pave the way for its widespread adoption and ultimately contribute to precision medicine.
期刊介绍：
Expert Review of Clinical Immunology (ISSN 1744-666X) provides expert analysis and commentary regarding the performance of new therapeutic and diagnostic modalities in clinical immunology. Members of the International Editorial Advisory Panel of Expert Review of Clinical Immunology are the forefront of their area of expertise. This panel works with our dedicated editorial team to identify the most important and topical review themes and the corresponding expert(s) most appropriate to provide commentary and analysis. All articles are subject to rigorous peer-review, and the finished reviews provide an essential contribution to decision-making in clinical immunology.
Articles focus on the following key areas:
• Therapeutic overviews of specific immunologic disorders highlighting optimal therapy and prospects for new medicines
• Performance and benefits of newly approved therapeutic agents
• New diagnostic approaches
• Screening and patient stratification
• Pharmacoeconomic studies
• New therapeutic indications for existing therapies
• Adverse effects, occurrence and reduction
• Prospects for medicines in late-stage trials approaching regulatory approval
• Novel treatment strategies
• Epidemiological studies
• Commentary and comparison of treatment guidelines
Topics include infection and immunity, inflammation, host defense mechanisms, congenital and acquired immunodeficiencies, anaphylaxis and allergy, systemic immune diseases, organ-specific inflammatory diseases, transplantation immunology, endocrinology and diabetes, cancer immunology, neuroimmunology and hematological diseases.
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