暴露于双酚A的雌性大鼠后代的性行为。

IF 0.6 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Bulletin of Experimental Biology and Medicine Pub Date : 2025-05-01 Epub Date: 2025-07-18 DOI:10.1007/s10517-025-06423-w

G V Bryukhin, D S Laskov, N V Gribachyova, D R Solyannikova

{"title":"暴露于双酚A的雌性大鼠后代的性行为。","authors":"G V Bryukhin, D S Laskov, N V Gribachyova, D R Solyannikova","doi":"10.1007/s10517-025-06423-w","DOIUrl":null,"url":null,"abstract":"We studied the effect of bisphenol A orally administrated to female rats on sexual behavior of their offspring. The males of the experimental group demonstrated significantly decreased number of approaches to a partition separating them from a receptive female; the copulatory rate during direct interaction with the female was also reduced. In females of the experimental group, the lordosis quotient and lordosis intensity were decreased. The revealed changes indicate that bisphenol A intoxication of female rats leads to significant disturbance of sexual behavior in their offspring of both sexes.","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"10-13"},"PeriodicalIF":0.6000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sexual Behavior of the Offspring of Female Rats Exposed to Bisphenol A.\",\"authors\":\"G V Bryukhin, D S Laskov, N V Gribachyova, D R Solyannikova\",\"doi\":\"10.1007/s10517-025-06423-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We studied the effect of bisphenol A orally administrated to female rats on sexual behavior of their offspring. The males of the experimental group demonstrated significantly decreased number of approaches to a partition separating them from a receptive female; the copulatory rate during direct interaction with the female was also reduced. In females of the experimental group, the lordosis quotient and lordosis intensity were decreased. The revealed changes indicate that bisphenol A intoxication of female rats leads to significant disturbance of sexual behavior in their offspring of both sexes.\",\"PeriodicalId\":9331,\"journal\":{\"name\":\"Bulletin of Experimental Biology and Medicine\",\"volume\":\" \",\"pages\":\"10-13\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of Experimental Biology and Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s10517-025-06423-w\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/18 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Experimental Biology and Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10517-025-06423-w","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/18 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}

引用次数: 0

摘要

我们研究了雌性大鼠口服双酚A对其后代性行为的影响。实验组的雄鼠接近与接受交配的雌鼠分开的区域的次数明显减少；与雌性直接接触时的交配率也降低了。实验组女性前凸商数和前凸强度均降低。这些变化表明，雌性大鼠双酚A中毒会导致其后代的性行为受到明显的干扰。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Sexual Behavior of the Offspring of Female Rats Exposed to Bisphenol A.

We studied the effect of bisphenol A orally administrated to female rats on sexual behavior of their offspring. The males of the experimental group demonstrated significantly decreased number of approaches to a partition separating them from a receptive female; the copulatory rate during direct interaction with the female was also reduced. In females of the experimental group, the lordosis quotient and lordosis intensity were decreased. The revealed changes indicate that bisphenol A intoxication of female rats leads to significant disturbance of sexual behavior in their offspring of both sexes.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Bulletin of Experimental Biology and Medicine 医学-医学：研究与实验

CiteScore

1.50

自引率

14.30%

发文量

265

审稿时长

2 months

期刊介绍： Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005. World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells. The Russian Volume Year is published in English from April.