Martin Kampamba, Pumulo Munawai, Remmy Sioma, Christabel Mwila Hikaambo, Steward Mudenda, Mukumbi Mutenda, Jean M Mukumbuta, Muchindu Hampango, Muzyamba Malambo, Gunet Mwalungali, Audrey Hamachila, Billy Chabalenge, Jimmy Hangoma, Mashebe Innocent Ngula, Bernard Appiah
{"title":"高等院校女生对长效暴露前注射预防艾滋病的认识和接受程度：一项多中心、基于院校的横断面研究","authors":"Martin Kampamba, Pumulo Munawai, Remmy Sioma, Christabel Mwila Hikaambo, Steward Mudenda, Mukumbi Mutenda, Jean M Mukumbuta, Muchindu Hampango, Muzyamba Malambo, Gunet Mwalungali, Audrey Hamachila, Billy Chabalenge, Jimmy Hangoma, Mashebe Innocent Ngula, Bernard Appiah","doi":"10.1186/s12889-025-22271-9","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Adolescent girls and young women (AGYW) in Zambia face an elevated risk of acquiring HIV. Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) is an effective scientific method to prevent new HIV infections. However, awareness and acceptability of LAI-PrEP among AGYW remain limited. Thus, we aimed to assess awareness and acceptability of LAI-PrEP among female students.</p><p><strong>Methods: </strong>This multi-center, institution-based cross-sectional study involved 760 female students from three universities in Lusaka, Zambia. Data were collected using a structured, self-administered questionnaire. Questions on acceptability and awareness were presented in a yes/no format. Data analysis was performed using STATA version 15.1.</p><p><strong>Results: </strong>Of the 760 participants, less than half, 349 (45.9%), were aware of injectable PrEP, with lectures being the most common source of information. In terms of acceptability, 531 (69.9%) of respondents indicated they would be willing to take LAI-PrEP once available. Biomedical science students were significantly less likely to accept injectable PrEP (AOR = 0.10, CI: 0.01-0.94, p = 0.044), as were those not at risk of HIV in the past three months (AOR = 0.41, CI: 0.21-0.81, p = 0.011). Conversely, knowing a partner's HIV status (AOR = 2.52, CI: 1.27-4.98, p = 0.0001) and being at risk of HIV in the past three months (AOR = 3.4, CI: 1.78-7.81, p = 0.011) were significantly associated with LAI-PrEP acceptability.</p><p><strong>Conclusion: </strong>The study revealed a notable gap in awareness of LAI-PrEP among participants, with less than half being informed about its existence. Despite this low awareness, a significant majority expressed a willingness to accept LAI-PrEP if it were made available to them. This indicates a strong potential for adoption of LAI-PrEP, contingent upon improved education and awareness efforts.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"2478"},"PeriodicalIF":3.6000,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269260/pdf/","citationCount":"0","resultStr":"{\"title\":\"Awareness and acceptability of long-acting injectable pre-exposure prophylaxis for HIV prevention among female students at tertiary learning institutions: a multi-center, institution-based cross-sectional study.\",\"authors\":\"Martin Kampamba, Pumulo Munawai, Remmy Sioma, Christabel Mwila Hikaambo, Steward Mudenda, Mukumbi Mutenda, Jean M Mukumbuta, Muchindu Hampango, Muzyamba Malambo, Gunet Mwalungali, Audrey Hamachila, Billy Chabalenge, Jimmy Hangoma, Mashebe Innocent Ngula, Bernard Appiah\",\"doi\":\"10.1186/s12889-025-22271-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Adolescent girls and young women (AGYW) in Zambia face an elevated risk of acquiring HIV. Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) is an effective scientific method to prevent new HIV infections. However, awareness and acceptability of LAI-PrEP among AGYW remain limited. Thus, we aimed to assess awareness and acceptability of LAI-PrEP among female students.</p><p><strong>Methods: </strong>This multi-center, institution-based cross-sectional study involved 760 female students from three universities in Lusaka, Zambia. Data were collected using a structured, self-administered questionnaire. Questions on acceptability and awareness were presented in a yes/no format. Data analysis was performed using STATA version 15.1.</p><p><strong>Results: </strong>Of the 760 participants, less than half, 349 (45.9%), were aware of injectable PrEP, with lectures being the most common source of information. In terms of acceptability, 531 (69.9%) of respondents indicated they would be willing to take LAI-PrEP once available. Biomedical science students were significantly less likely to accept injectable PrEP (AOR = 0.10, CI: 0.01-0.94, p = 0.044), as were those not at risk of HIV in the past three months (AOR = 0.41, CI: 0.21-0.81, p = 0.011). Conversely, knowing a partner's HIV status (AOR = 2.52, CI: 1.27-4.98, p = 0.0001) and being at risk of HIV in the past three months (AOR = 3.4, CI: 1.78-7.81, p = 0.011) were significantly associated with LAI-PrEP acceptability.</p><p><strong>Conclusion: </strong>The study revealed a notable gap in awareness of LAI-PrEP among participants, with less than half being informed about its existence. Despite this low awareness, a significant majority expressed a willingness to accept LAI-PrEP if it were made available to them. This indicates a strong potential for adoption of LAI-PrEP, contingent upon improved education and awareness efforts.</p>\",\"PeriodicalId\":9039,\"journal\":{\"name\":\"BMC Public Health\",\"volume\":\"25 1\",\"pages\":\"2478\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-07-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269260/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Public Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12889-025-22271-9\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Public Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12889-025-22271-9","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
摘要
背景：赞比亚的少女和年轻妇女（AGYW）面临着感染艾滋病毒的高风险。长效注射暴露前预防（LAI-PrEP）是预防HIV新发感染的有效科学方法。然而，老年妇女对LAI-PrEP的认识和接受程度仍然有限。因此，我们旨在评估女生对LAI-PrEP的认知和接受程度。方法：这项多中心、基于机构的横断面研究涉及赞比亚卢萨卡三所大学的760名女学生。数据收集采用结构化的，自我管理的问卷。关于可接受性和认识的问题以是/否的形式提出。使用STATA 15.1版本进行数据分析。结果：在760名参与者中，不到一半，349人（45.9%），知道注射PrEP，讲座是最常见的信息来源。在可接受性方面，531名（69.9%）受访者表示，一旦有了ai - prep，他们愿意接受。生物医学专业的学生接受注射PrEP的可能性较低（AOR = 0.10, CI: 0.01-0.94, p = 0.044），过去三个月内没有艾滋病毒感染风险的学生接受注射PrEP的可能性也较低（AOR = 0.41, CI: 0.21-0.81, p = 0.011）。相反，了解伴侣的艾滋病毒状况（AOR = 2.52, CI: 1.27 ~ 4.98, p = 0.0001）和过去三个月内是否有感染艾滋病毒的风险（AOR = 3.4, CI: 1.78 ~ 7.81, p = 0.011）与LAI-PrEP的可接受性显著相关。结论：该研究揭示了参与者对LAI-PrEP的认识存在显着差距，不到一半的人被告知其存在。尽管这种认识很低，但绝大多数人表示，如果向他们提供lei - prep，他们愿意接受。这表明，在教育和提高认识工作得到改善的情况下，采用艾滋病预防措施的潜力很大。
Awareness and acceptability of long-acting injectable pre-exposure prophylaxis for HIV prevention among female students at tertiary learning institutions: a multi-center, institution-based cross-sectional study.
Background: Adolescent girls and young women (AGYW) in Zambia face an elevated risk of acquiring HIV. Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) is an effective scientific method to prevent new HIV infections. However, awareness and acceptability of LAI-PrEP among AGYW remain limited. Thus, we aimed to assess awareness and acceptability of LAI-PrEP among female students.
Methods: This multi-center, institution-based cross-sectional study involved 760 female students from three universities in Lusaka, Zambia. Data were collected using a structured, self-administered questionnaire. Questions on acceptability and awareness were presented in a yes/no format. Data analysis was performed using STATA version 15.1.
Results: Of the 760 participants, less than half, 349 (45.9%), were aware of injectable PrEP, with lectures being the most common source of information. In terms of acceptability, 531 (69.9%) of respondents indicated they would be willing to take LAI-PrEP once available. Biomedical science students were significantly less likely to accept injectable PrEP (AOR = 0.10, CI: 0.01-0.94, p = 0.044), as were those not at risk of HIV in the past three months (AOR = 0.41, CI: 0.21-0.81, p = 0.011). Conversely, knowing a partner's HIV status (AOR = 2.52, CI: 1.27-4.98, p = 0.0001) and being at risk of HIV in the past three months (AOR = 3.4, CI: 1.78-7.81, p = 0.011) were significantly associated with LAI-PrEP acceptability.
Conclusion: The study revealed a notable gap in awareness of LAI-PrEP among participants, with less than half being informed about its existence. Despite this low awareness, a significant majority expressed a willingness to accept LAI-PrEP if it were made available to them. This indicates a strong potential for adoption of LAI-PrEP, contingent upon improved education and awareness efforts.
期刊介绍：
BMC Public Health is an open access, peer-reviewed journal that considers articles on the epidemiology of disease and the understanding of all aspects of public health. The journal has a special focus on the social determinants of health, the environmental, behavioral, and occupational correlates of health and disease, and the impact of health policies, practices and interventions on the community.
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