{"title":"一种适用于果蔬解毒的沙林类似物黄色发光开启检测降解分子光电器件","authors":"Shubham Lama, Sabbir Ahamed, Najmin Tohora, Jyoti Chourasia, Ayan Kumar Mahanty, Shraddha Rai, Upika Darnal, Subekchha Pradhan, Sudhir Kumar Das","doi":"10.1002/bio.70258","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Nerve agents seriously threaten the viability of the contemporary environment and public health. In the current contribution, we have introduced a Schiff base-based probe, <b>MIDA</b> to “detect and degrade” sarin simulant, diethyl chlorophosphate (DCP) in solution and gaseous phases. <b>MIDA</b> is highly selective and sensitive towards DCP emitting a highly intensified yellow fluorescence having detection and quantification limits within the μM range. It was shown that DCP could be identified in a combination of similar hazardous analytes using a convenient strained paper strip-based assay. DCP vapor was identified via a dip-stick and dip vial conical flask experiment, which could be a useful photonic tool for selective detection of sarin in real threat scenarios. To validate DCP detection even in a variety of soil types, including sand, field, and clay, we also demonstrated soil sample analysis using diverse DCP-spiked soils. A smartphone-based detection method has also been demonstrated to detect and quantify DCP and may be helpful for on-spot sarin detection. Additionally, when Zn<sup>2+</sup> ions are introduced, the <b>MIDA</b>-DCP pair degrades into nontoxic forms. <b>MIDA</b> is a highly sensitive, selective, and “detect and degrade” probe for the detection and degradation of DCP, a toxic nerve agent sarin's simulant in hazardous circumstances.</p>\n </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"40 7","pages":""},"PeriodicalIF":3.0000,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Yellow Color Emitting Turn-On Detect and Degrade Molecular Optode for Sarin Analog Applicable for Detoxification of Fruits and Vegetables\",\"authors\":\"Shubham Lama, Sabbir Ahamed, Najmin Tohora, Jyoti Chourasia, Ayan Kumar Mahanty, Shraddha Rai, Upika Darnal, Subekchha Pradhan, Sudhir Kumar Das\",\"doi\":\"10.1002/bio.70258\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p>Nerve agents seriously threaten the viability of the contemporary environment and public health. In the current contribution, we have introduced a Schiff base-based probe, <b>MIDA</b> to “detect and degrade” sarin simulant, diethyl chlorophosphate (DCP) in solution and gaseous phases. <b>MIDA</b> is highly selective and sensitive towards DCP emitting a highly intensified yellow fluorescence having detection and quantification limits within the μM range. It was shown that DCP could be identified in a combination of similar hazardous analytes using a convenient strained paper strip-based assay. DCP vapor was identified via a dip-stick and dip vial conical flask experiment, which could be a useful photonic tool for selective detection of sarin in real threat scenarios. To validate DCP detection even in a variety of soil types, including sand, field, and clay, we also demonstrated soil sample analysis using diverse DCP-spiked soils. A smartphone-based detection method has also been demonstrated to detect and quantify DCP and may be helpful for on-spot sarin detection. Additionally, when Zn<sup>2+</sup> ions are introduced, the <b>MIDA</b>-DCP pair degrades into nontoxic forms. <b>MIDA</b> is a highly sensitive, selective, and “detect and degrade” probe for the detection and degradation of DCP, a toxic nerve agent sarin's simulant in hazardous circumstances.</p>\\n </div>\",\"PeriodicalId\":49902,\"journal\":{\"name\":\"Luminescence\",\"volume\":\"40 7\",\"pages\":\"\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2025-07-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Luminescence\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/bio.70258\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Luminescence","FirstCategoryId":"92","ListUrlMain":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/bio.70258","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
A Yellow Color Emitting Turn-On Detect and Degrade Molecular Optode for Sarin Analog Applicable for Detoxification of Fruits and Vegetables
Nerve agents seriously threaten the viability of the contemporary environment and public health. In the current contribution, we have introduced a Schiff base-based probe, MIDA to “detect and degrade” sarin simulant, diethyl chlorophosphate (DCP) in solution and gaseous phases. MIDA is highly selective and sensitive towards DCP emitting a highly intensified yellow fluorescence having detection and quantification limits within the μM range. It was shown that DCP could be identified in a combination of similar hazardous analytes using a convenient strained paper strip-based assay. DCP vapor was identified via a dip-stick and dip vial conical flask experiment, which could be a useful photonic tool for selective detection of sarin in real threat scenarios. To validate DCP detection even in a variety of soil types, including sand, field, and clay, we also demonstrated soil sample analysis using diverse DCP-spiked soils. A smartphone-based detection method has also been demonstrated to detect and quantify DCP and may be helpful for on-spot sarin detection. Additionally, when Zn2+ ions are introduced, the MIDA-DCP pair degrades into nontoxic forms. MIDA is a highly sensitive, selective, and “detect and degrade” probe for the detection and degradation of DCP, a toxic nerve agent sarin's simulant in hazardous circumstances.
期刊介绍:
Luminescence provides a forum for the publication of original scientific papers, short communications, technical notes and reviews on fundamental and applied aspects of all forms of luminescence, including bioluminescence, chemiluminescence, electrochemiluminescence, sonoluminescence, triboluminescence, fluorescence, time-resolved fluorescence and phosphorescence. Luminescence publishes papers on assays and analytical methods, instrumentation, mechanistic and synthetic studies, basic biology and chemistry.
Luminescence also publishes details of forthcoming meetings, information on new products, and book reviews. A special feature of the Journal is surveys of the recent literature on selected topics in luminescence.