魔芋低聚糖的提取、表征、生物活性及应用前景综述

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers Pub Date : 2025-07-13 DOI:10.1016/j.carbpol.2025.124053

Xiaoyan Chang , Yi Han , Cuiping Yang , Liyuan Gao , Zhuoyi Wang , Ying Meng , Min Zhang , Xiang Yang , Zhitao Jiang

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引用次数: 0

摘要

魔芋因其在药用和营养方面的双重作用而受到广泛关注，其中魔芋低聚糖（KOS）作为一种生物活性化合物受到了特别的关注。KOS具有广泛的生物活性，包括通便、免疫调节、糖脂代谢调节、抗氧化、抗疲劳、抗炎、成骨和益生元作用。尽管在其提取、纯化和表征方面取得了进展，但对其结构特性和作用机制的深入了解仍然是必不可少的。本文系统地综述了KOS的提取、分离和纯化技术，以及它的理化性质、生物活性、构效关系和潜在的应用。此外，对KOS的毒性和安全性进行了严格评估。通过对这些方面的整合，本文综述为支持基于kos的功能食品的开发提供了理论和技术见解，突出了其在食品和营养保健行业的潜力。

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Advance in the extraction, characterization, bioactivities, and application prospects of konjac oligosaccharide: A comprehensive review

Konjac has garnered significant attention for its dual roles in medicinal and nutritional applications, with konjac oligosaccharide (KOS) emerging as a bioactive compound of particular interest. KOS exhibits a wide range of biological activities, including laxative, immunomodulatory, glucolipid metabolism regulatory, antioxidative, antifatigue, anti-inflammatory, osteogenic, and prebiotic effects. Despite advances in its extraction, purification, and characterization, a deeper understanding of its structural properties and mechanisms of action remains essential. This review systematically examines the extraction, separation, and purification techniques of KOS, alongside its physicochemical properties, biological activities, structure-activity relationships, and potential applications. Additionally, the toxicity and safety profile of KOS are critically evaluated. By integrating these aspects, this review provides theoretical and technical insights to support the development of KOS-based functional foods, highlighting its potential in the food and nutraceutical industries.

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来源期刊

Carbohydrate Polymers 化学-高分子科学

CiteScore

22.40

自引率

8.00%

发文量

1286

审稿时长

47 days

期刊介绍： Carbohydrate Polymers stands as a prominent journal in the glycoscience field, dedicated to exploring and harnessing the potential of polysaccharides with applications spanning bioenergy, bioplastics, biomaterials, biorefining, chemistry, drug delivery, food, health, nanotechnology, packaging, paper, pharmaceuticals, medicine, oil recovery, textiles, tissue engineering, wood, and various aspects of glycoscience. The journal emphasizes the central role of well-characterized carbohydrate polymers, highlighting their significance as the primary focus rather than a peripheral topic. Each paper must prominently feature at least one named carbohydrate polymer, evident in both citation and title, with a commitment to innovative research that advances scientific knowledge.