帕金森病的注意/工作记忆和执行功能：回顾、批评和建议。

IF 7.6 1区医学 Q1 CLINICAL NEUROLOGY

Movement Disorders Pub Date : 2025-07-18 DOI:10.1002/mds.30293

Roberta Biundo,Ondrej Bezdicek,Davide Maria Cammisuli,Brenna Cholerton,John C Dalrymple-Alford,Nicola Edelstyn,Eleonora Fiorenzato,Erin Holker,Saul Martinez-Horta,Alice Martini,Gabriella Santangelo,Barbara Segura,Chiara Siri,Alexander Tröster,Tiago A Mestre,Álvaro Sánchez Ferro,Michelle Hyczy de Siqueira Tosin,Matej Skorvanek,Daniel Weintraub,Gert J Geurtsen,

{"title":"帕金森病的注意/工作记忆和执行功能：回顾、批评和建议。","authors":"Roberta Biundo,Ondrej Bezdicek,Davide Maria Cammisuli,Brenna Cholerton,John C Dalrymple-Alford,Nicola Edelstyn,Eleonora Fiorenzato,Erin Holker,Saul Martinez-Horta,Alice Martini,Gabriella Santangelo,Barbara Segura,Chiara Siri,Alexander Tröster,Tiago A Mestre,Álvaro Sánchez Ferro,Michelle Hyczy de Siqueira Tosin,Matej Skorvanek,Daniel Weintraub,Gert J Geurtsen, ","doi":"10.1002/mds.30293","DOIUrl":null,"url":null,"abstract":"BACKGROUND\r\nCognitive impairment in Parkinson's disease (PD) is a well-established non-motor complication that significantly affects the quality of life and well-being of both patients and care partners. To optimally detect mild cognitive impairment or dementia, extensive neuropsychological assessment is essential. A wide range of cognitive tests and clinical outcome assessments have been used in clinical settings, often without regard to their clinimetric quality.\r\n\r\nMETHODS\r\nWe performed a literature review of tests assessing attention/working memory and executive domains in PD (tests on other domains are included in an accompanying review). The selected tests were evaluated for their clinimetric properties and categorized by a panel of experts as \"recommended,\" \"recommended with caveats,\" \"suggested,\" or \"listed\" according to the International Parkinson and Movement Disorder Society Clinical Outcome Assessment Scientific Evaluation Committee guidelines.\r\n\r\nRESULTS\r\nA total of 30 tests were reviewed. Eight tests were \"recommended,\" including four tests assessing attention/working memory abilities (WAIS-IV Digit Span, Coding and Symbol Search subtests, and Trail Making Test) and four tests assessing executive abilities (WAIS-IV Similarities, Wisconsin Card Sorting Test, Fluency Tests, and Stroop Color-Word Test). These tests demonstrated good to excellent levels of reliability and validity, have normative datasets, and are sensitive to change. Eight other tests were \"recommended with caveats\", eleven were \"suggested,\" and three were \"listed.\"\r\n\r\nCONCLUSIONS\r\nThe recommended tests for attention/working memory and executive functioning in PD can guide PD cognitive assessment. Other tests were identified as potentially useful; however, caution is advised due to their clinimetric limitations. Further validation studies are required for these tests. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.","PeriodicalId":213,"journal":{"name":"Movement Disorders","volume":"48 1","pages":""},"PeriodicalIF":7.6000,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Attention/Working Memory and Executive Function in Parkinson's Disease: Review, Critique, and Recommendations.\",\"authors\":\"Roberta Biundo,Ondrej Bezdicek,Davide Maria Cammisuli,Brenna Cholerton,John C Dalrymple-Alford,Nicola Edelstyn,Eleonora Fiorenzato,Erin Holker,Saul Martinez-Horta,Alice Martini,Gabriella Santangelo,Barbara Segura,Chiara Siri,Alexander Tröster,Tiago A Mestre,Álvaro Sánchez Ferro,Michelle Hyczy de Siqueira Tosin,Matej Skorvanek,Daniel Weintraub,Gert J Geurtsen, \",\"doi\":\"10.1002/mds.30293\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"BACKGROUND\\r\\nCognitive impairment in Parkinson's disease (PD) is a well-established non-motor complication that significantly affects the quality of life and well-being of both patients and care partners. To optimally detect mild cognitive impairment or dementia, extensive neuropsychological assessment is essential. A wide range of cognitive tests and clinical outcome assessments have been used in clinical settings, often without regard to their clinimetric quality.\\r\\n\\r\\nMETHODS\\r\\nWe performed a literature review of tests assessing attention/working memory and executive domains in PD (tests on other domains are included in an accompanying review). The selected tests were evaluated for their clinimetric properties and categorized by a panel of experts as \\\"recommended,\\\" \\\"recommended with caveats,\\\" \\\"suggested,\\\" or \\\"listed\\\" according to the International Parkinson and Movement Disorder Society Clinical Outcome Assessment Scientific Evaluation Committee guidelines.\\r\\n\\r\\nRESULTS\\r\\nA total of 30 tests were reviewed. Eight tests were \\\"recommended,\\\" including four tests assessing attention/working memory abilities (WAIS-IV Digit Span, Coding and Symbol Search subtests, and Trail Making Test) and four tests assessing executive abilities (WAIS-IV Similarities, Wisconsin Card Sorting Test, Fluency Tests, and Stroop Color-Word Test). These tests demonstrated good to excellent levels of reliability and validity, have normative datasets, and are sensitive to change. Eight other tests were \\\"recommended with caveats\\\", eleven were \\\"suggested,\\\" and three were \\\"listed.\\\"\\r\\n\\r\\nCONCLUSIONS\\r\\nThe recommended tests for attention/working memory and executive functioning in PD can guide PD cognitive assessment. Other tests were identified as potentially useful; however, caution is advised due to their clinimetric limitations. Further validation studies are required for these tests. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.\",\"PeriodicalId\":213,\"journal\":{\"name\":\"Movement Disorders\",\"volume\":\"48 1\",\"pages\":\"\"},\"PeriodicalIF\":7.6000,\"publicationDate\":\"2025-07-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Movement Disorders\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/mds.30293\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Movement Disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/mds.30293","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

摘要

帕金森病（PD）的认知障碍是一种公认的非运动并发症，显著影响患者及其护理伙伴的生活质量和福祉。为了最佳地检测轻度认知障碍或痴呆，广泛的神经心理学评估是必不可少的。广泛的认知测试和临床结果评估已在临床环境中使用，往往不考虑其临床质量。方法我们对PD患者的注意力/工作记忆和执行领域的测试进行了文献综述（其他领域的测试包括在随附的综述中）。根据国际帕金森和运动障碍学会临床结果评估科学评估委员会的指导方针，选定的测试根据其临床计量学特性进行评估，并由专家小组分类为“推荐”、“有警告的推荐”、“建议”或“列出”。结果共回顾了30例tsa试验。“推荐”了8项测试，包括4项评估注意力/工作记忆能力的测试（WAIS-IV数字广度、编码和符号搜索子测试，以及踪迹制作测试）和4项评估执行能力的测试（WAIS-IV相似性、威斯康星卡片分类测试、流畅性测试和Stroop颜色-单词测试）。这些测试显示了良好到优秀的信度和效度水平，具有规范的数据集，并且对变化敏感。其他8项测试是“建议附带说明”，11项是“建议”，3项是“列出”。结论推荐的PD注意/工作记忆和执行功能测试可指导PD认知评估。确定了其他可能有用的测试；然而，由于其临床局限性，建议谨慎使用。这些试验需要进一步的验证研究。©2025作者。Wiley期刊有限责任公司代表国际帕金森和运动障碍学会出版的《运动障碍》。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Attention/Working Memory and Executive Function in Parkinson's Disease: Review, Critique, and Recommendations.

BACKGROUND Cognitive impairment in Parkinson's disease (PD) is a well-established non-motor complication that significantly affects the quality of life and well-being of both patients and care partners. To optimally detect mild cognitive impairment or dementia, extensive neuropsychological assessment is essential. A wide range of cognitive tests and clinical outcome assessments have been used in clinical settings, often without regard to their clinimetric quality. METHODS We performed a literature review of tests assessing attention/working memory and executive domains in PD (tests on other domains are included in an accompanying review). The selected tests were evaluated for their clinimetric properties and categorized by a panel of experts as "recommended," "recommended with caveats," "suggested," or "listed" according to the International Parkinson and Movement Disorder Society Clinical Outcome Assessment Scientific Evaluation Committee guidelines. RESULTS A total of 30 tests were reviewed. Eight tests were "recommended," including four tests assessing attention/working memory abilities (WAIS-IV Digit Span, Coding and Symbol Search subtests, and Trail Making Test) and four tests assessing executive abilities (WAIS-IV Similarities, Wisconsin Card Sorting Test, Fluency Tests, and Stroop Color-Word Test). These tests demonstrated good to excellent levels of reliability and validity, have normative datasets, and are sensitive to change. Eight other tests were "recommended with caveats", eleven were "suggested," and three were "listed." CONCLUSIONS The recommended tests for attention/working memory and executive functioning in PD can guide PD cognitive assessment. Other tests were identified as potentially useful; however, caution is advised due to their clinimetric limitations. Further validation studies are required for these tests. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Movement Disorders 医学-临床神经学

CiteScore

13.30

自引率

8.10%

发文量

371

审稿时长

12 months

期刊介绍： Movement Disorders publishes a variety of content types including Reviews, Viewpoints, Full Length Articles, Historical Reports, Brief Reports, and Letters. The journal considers original manuscripts on topics related to the diagnosis, therapeutics, pharmacology, biochemistry, physiology, etiology, genetics, and epidemiology of movement disorders. Appropriate topics include Parkinsonism, Chorea, Tremors, Dystonia, Myoclonus, Tics, Tardive Dyskinesia, Spasticity, and Ataxia.