{"title":"在消除母婴传播的背景下评估配偶检测对感染梅毒孕妇的有效性：一项中国东南部的多中心研究。","authors":"Xiaomeng Xue, Xinxin Huang, Guihua Liu, Xiumin Jiang, Wenzhao Lin, Yongfan Chen, Chengyu Huang","doi":"10.2147/RMHP.S531584","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Syphilis during pregnancy poses significant risks to maternal and neonatal health. Spousal testing is crucial for preventing congenital syphilis transmission. This study assessed spousal testing rates among syphilis-positive pregnant women to guide public health interventions.</p><p><strong>Methods: </strong>This multicenter effectiveness study was conducted in Southeast China, utilizing data from the Chinese HIV/AIDS, Syphilis, and Hepatitis B Prevention Information System between 2018 to 2024. Proportions were used to describe the sociodemographic characteristics of pregnant women with syphilis. Univariate and multivariate unconditional logistic regression models were used to analyze the factors associated with the testing status of spouses of pregnant women with syphilis.</p><p><strong>Results: </strong>A total of 4,875 spouses were tested for syphilis. Older gestational age at the first prenatal visit (aOR = 1.014, 95% CI: 1.007-1.022) and at delivery (aOR = 1.273, 95% CI: 1.011-1.602) were associated with lower rates of spousal testing. Spouses of women reported in 2022-2023 (aOR = 1.840, 95% CI: 1.465-2.311) had a higher likelihood of being untested. Unmarried status (aOR = 1.181, 95% CI: 1.022-1.364), junior high school education and below (aOR = 1.244, 95% CI: 1.121-1.381), no history of infection (aOR = 2.281, 95% CI: 2.073-2.510), and prenatal care in Grade II hospitals (aOR = 0.1.292, 95% CI: 1.140-1.464) were risk factors for spousal testing.</p><p><strong>Conclusion: </strong>From 2018 to 2024, the spousal testing rate was 60%, with a syphilis positivity rate of 14.7%. Data revealed multiple risk factors, such as a late first pregnancy test, advanced age, unmarried status, lower education level, no history of syphilis infection, and selection of prenatal care in Grade II hospitals as delivery facilities. Recommendations include establishing specialized clinics, post-test spousal counseling, and routine spousal testing.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"2423-2433"},"PeriodicalIF":2.0000,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266062/pdf/","citationCount":"0","resultStr":"{\"title\":\"Evaluating the Effectiveness of Spousal Testing Among Syphilis-Infected Pregnant Women in the Context of Mother-to-Child Transmission Elimination: A Multicenter Study in Southeastern China.\",\"authors\":\"Xiaomeng Xue, Xinxin Huang, Guihua Liu, Xiumin Jiang, Wenzhao Lin, Yongfan Chen, Chengyu Huang\",\"doi\":\"10.2147/RMHP.S531584\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Syphilis during pregnancy poses significant risks to maternal and neonatal health. Spousal testing is crucial for preventing congenital syphilis transmission. This study assessed spousal testing rates among syphilis-positive pregnant women to guide public health interventions.</p><p><strong>Methods: </strong>This multicenter effectiveness study was conducted in Southeast China, utilizing data from the Chinese HIV/AIDS, Syphilis, and Hepatitis B Prevention Information System between 2018 to 2024. Proportions were used to describe the sociodemographic characteristics of pregnant women with syphilis. Univariate and multivariate unconditional logistic regression models were used to analyze the factors associated with the testing status of spouses of pregnant women with syphilis.</p><p><strong>Results: </strong>A total of 4,875 spouses were tested for syphilis. Older gestational age at the first prenatal visit (aOR = 1.014, 95% CI: 1.007-1.022) and at delivery (aOR = 1.273, 95% CI: 1.011-1.602) were associated with lower rates of spousal testing. Spouses of women reported in 2022-2023 (aOR = 1.840, 95% CI: 1.465-2.311) had a higher likelihood of being untested. Unmarried status (aOR = 1.181, 95% CI: 1.022-1.364), junior high school education and below (aOR = 1.244, 95% CI: 1.121-1.381), no history of infection (aOR = 2.281, 95% CI: 2.073-2.510), and prenatal care in Grade II hospitals (aOR = 0.1.292, 95% CI: 1.140-1.464) were risk factors for spousal testing.</p><p><strong>Conclusion: </strong>From 2018 to 2024, the spousal testing rate was 60%, with a syphilis positivity rate of 14.7%. Data revealed multiple risk factors, such as a late first pregnancy test, advanced age, unmarried status, lower education level, no history of syphilis infection, and selection of prenatal care in Grade II hospitals as delivery facilities. Recommendations include establishing specialized clinics, post-test spousal counseling, and routine spousal testing.</p>\",\"PeriodicalId\":56009,\"journal\":{\"name\":\"Risk Management and Healthcare Policy\",\"volume\":\"18 \",\"pages\":\"2423-2433\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-07-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266062/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Risk Management and Healthcare Policy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2147/RMHP.S531584\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Risk Management and Healthcare Policy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/RMHP.S531584","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
Evaluating the Effectiveness of Spousal Testing Among Syphilis-Infected Pregnant Women in the Context of Mother-to-Child Transmission Elimination: A Multicenter Study in Southeastern China.
Purpose: Syphilis during pregnancy poses significant risks to maternal and neonatal health. Spousal testing is crucial for preventing congenital syphilis transmission. This study assessed spousal testing rates among syphilis-positive pregnant women to guide public health interventions.
Methods: This multicenter effectiveness study was conducted in Southeast China, utilizing data from the Chinese HIV/AIDS, Syphilis, and Hepatitis B Prevention Information System between 2018 to 2024. Proportions were used to describe the sociodemographic characteristics of pregnant women with syphilis. Univariate and multivariate unconditional logistic regression models were used to analyze the factors associated with the testing status of spouses of pregnant women with syphilis.
Results: A total of 4,875 spouses were tested for syphilis. Older gestational age at the first prenatal visit (aOR = 1.014, 95% CI: 1.007-1.022) and at delivery (aOR = 1.273, 95% CI: 1.011-1.602) were associated with lower rates of spousal testing. Spouses of women reported in 2022-2023 (aOR = 1.840, 95% CI: 1.465-2.311) had a higher likelihood of being untested. Unmarried status (aOR = 1.181, 95% CI: 1.022-1.364), junior high school education and below (aOR = 1.244, 95% CI: 1.121-1.381), no history of infection (aOR = 2.281, 95% CI: 2.073-2.510), and prenatal care in Grade II hospitals (aOR = 0.1.292, 95% CI: 1.140-1.464) were risk factors for spousal testing.
Conclusion: From 2018 to 2024, the spousal testing rate was 60%, with a syphilis positivity rate of 14.7%. Data revealed multiple risk factors, such as a late first pregnancy test, advanced age, unmarried status, lower education level, no history of syphilis infection, and selection of prenatal care in Grade II hospitals as delivery facilities. Recommendations include establishing specialized clinics, post-test spousal counseling, and routine spousal testing.
期刊介绍：
Risk Management and Healthcare Policy is an international, peer-reviewed, open access journal focusing on all aspects of public health, policy and preventative measures to promote good health and improve morbidity and mortality in the population. Specific topics covered in the journal include:
Public and community health
Policy and law
Preventative and predictive healthcare
Risk and hazard management
Epidemiology, detection and screening
Lifestyle and diet modification
Vaccination and disease transmission/modification programs
Health and safety and occupational health
Healthcare services provision
Health literacy and education
Advertising and promotion of health issues
Health economic evaluations and resource management
Risk Management and Healthcare Policy focuses on human interventional and observational research. The journal welcomes submitted papers covering original research, clinical and epidemiological studies, reviews and evaluations, guidelines, expert opinion and commentary, and extended reports. Case reports will only be considered if they make a valuable and original contribution to the literature. The journal does not accept study protocols, animal-based or cell line-based studies.
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