金离子涂层与银离子涂层在种植体-基牙界面抗菌效果的比较研究。

IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE
Amritha Chandran, Shalini Joshi, Sunil Dhaded, Y Anand Kumar, Chandrashekar Sajjan, Priyanka Konin
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引用次数: 0

摘要

目的:评价金属离子(银和金)在种植体-基牙界面(IAI)引起种植体周围炎的抗菌效果,比较其抗菌性能。研究设置与设计:本研究为体外实验研究。材料和方法:共90个标本,45个钛合金(Ti-6Al-4V, V级)和45个不锈钢(315L SS)(基台)替代盘,经过连续研磨、抛光和清洁,用溅射技术涂覆金(Au)和银(Ag)离子,然后用琼脂盘扩散法检测引起种植体周围炎的革兰氏阴性微生物的抗菌效果。测量并记录每个样品周围的抑制带(ZOI)。采用统计学分析:各组平均抑制区数据采用Tukey多重比较检验和单因素方差分析进行统计学分析。结果:结果表明:镀金钛合金-不锈钢(TiAu - ssau)和镀银钛合金-不锈钢(TiAg-SSAg)的抗菌效果显著高于未镀金钛合金-不锈钢(Ti-SS),镀金组的平均ZOI值为24.6mm (Prevotella intermedia),镀银组的平均ZOI值为17 mm,平均抑制区为10mm;结论:金属离子涂层(Au和Ag)对钛合金和不锈钢进行表面改性,可显著减少种植体周围炎的症状,从而使种植体获得持久成功。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative evaluation of antimicrobial efficacy at the implant-abutment interface using gold and silver ion coatings - An in vitro study.

Aim: The aim of the study is to assess the antimicrobial efficacy at Implant-Abutment Interface (IAI) coated with metal ions (silver and gold) causing peri-implantitis, with the objective of comparing its antimicrobial properties.

Study setting and design: The study conducted is an in vitro experimental study.

Material and methods: A total of 90 specimens 45 Titanium alloy discs substitute for Implant (Ti-6Al-4V, Grade V) and 45 Stainless Steel (315L SS) disc substitute for Abutment were serially ground, polished and cleaned to be coated with gold (Au) and silver (Ag) ions by sputtering technique which was later tested for antimicrobial efficacy by means of agar disk diffusion method with gram negative microorganisms causing peri-implantitis, the measurement of inhibition zone (ZOI) encircling each sample were taken and noted.

Statistical analysis used: The mean zone of inhibition data for all the groups were subjected for statistical analysis by Tukey's multiple comparison test and one way ANOVA.

Results: The results showed that the antimicrobial efficacy of gold coated Titanium alloy-Stainless steel, (TiAu -SSAu) and Silver coated Titanium- stainless steel (TiAg-SSAg) were significantly higher with a mean ZOI value of 24.6mm (Prevotella intermedia) for gold coated and 17 mm for silver coated groups compared to Uncoated group Titanium alloy- stainless steel (Ti-SS) with a mean zone of inhibition of 10mm, also proved by Tukeys multiple comparison test with statistical significant difference in the antibacterial activity of gold coated group compared to other groups where p <0.0001 against Porphyromonas Gingivalis, Prevotella Intermedia and Aggregatibacter Actinomyces.

Conclusions: The surface modification of titanium alloy and stainless steel with metal ion coating (Au and Ag) significantly reduces the signs of peri-implantitis and thus leading to lasting success of implants.

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来源期刊
The Journal of Indian Prosthodontic Society
The Journal of Indian Prosthodontic Society DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
2.20
自引率
8.30%
发文量
26
审稿时长
20 weeks
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