羟基四甲基哌啶氧化物和柠檬酸三酯（四甲基羟哌啶醇）在化妆品中的安全性评价。

IF 1 4区医学 Q4 PHARMACOLOGY & PHARMACY

International Journal of Toxicology Pub Date : 2025-08-01 Epub Date: 2025-07-17 DOI:10.1177/10915818251342562

Preethi S Raj, Wilma F Bergfeld, Donald V Belsito, David E Cohen, Curtis D Klaassen, Daniel C Liebler, James G Marks, Lisa A Peterson, Ronald C Shank, Thomas J Slaga, Paul W Snyder, Monice M Fiume, Bart Heldreth

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引用次数: 0

摘要

化妆品成分安全专家小组（专家组）评估了化妆品配方中使用的羟基四甲基哌啶氧化物和柠檬酸三酯（四甲基羟哌啶醇）的安全性。据报道，这些成分分别具有抗氧化剂和光稳定剂的作用。评估小组考虑了现有的数据并得出结论，在目前的使用实践和本安全评估中描述的浓度下，羟基四甲基哌啶氧化物和Tris（四甲基羟哌啶醇）柠檬酸盐在化妆品中是安全的。

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Safety Assessment of Hydroxy Tetramethylpiperidine Oxide and Tris(Tetramethylhydroxypiperidinol) Citrate as Used in Cosmetics.

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Hydroxy Tetramethylpiperidine Oxide and Tris(Tetramethylhydroxypiperidinol) Citrate as used in cosmetic formulations. These ingredients are reported to function as an antioxidant and a light stabilizer, respectively. The Panel considered the available data and concluded that Hydroxy Tetramethylpiperidine Oxide and Tris(Tetramethylhydroxypiperidinol) Citrate are safe in cosmetics in the present practices of use and concentration described in this safety assessment.

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来源期刊

International Journal of Toxicology 医学-毒理学

CiteScore

3.40

自引率

4.50%

发文量

审稿时长

4.5 months

期刊介绍： The International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Review Expert Panel.