1990年至2021年全球、地区和国家儿童中耳炎流行病学

IF 2.1 3区 医学 Q2 PEDIATRICS
Frontiers in Pediatrics Pub Date : 2025-07-02 eCollection Date: 2025-01-01 DOI:10.3389/fped.2025.1513629
HanYu Wang, XiaoYu Zeng, Xin Miao, BoWen Yang, ShiPeng Zhang, QinWei Fu, QinXiu Zhang, Mi Tang
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引用次数: 0

摘要

背景:中耳炎(OM)是一种常见的耳部疾病,特别是在儿童中,对生活质量有重大影响。本研究旨在利用2021年全球疾病负担(GBD)研究的数据,阐明1990-2021年0-14岁年龄组中与OM相关的全球患病率和残疾调整生命年(DALYs)。方法:我们的研究对GBD 2021报告中的OM数据进行了全面分析,检查了32年来204个国家和地区的OM患病率和与OM相关的DALYs。数据按年龄、性别、年份、地理区域和社会人口指数(SDI)分层。使用估计的年变化百分比(EAPC)计算来评估时间趋势。此外,对全球儿童OM风险归因进行了分析,并应用贝叶斯年龄-时期-队列(BAPC)模型预测2021-2035年全球儿童OM负担。结果:2021年,全球儿童OM负担仍然很大,发病率为297,243,470例,年龄标准化患病率为每10万人14,775例。OM导致全球1,035,749例DALY,年龄标准化DALY率为每10万人51.48例。从区域来看,年龄标准化的OM患病率最高的地区是撒哈拉以南非洲东部、南亚和撒哈拉以南非洲西部,而中欧、东亚和高收入亚太地区的患病率最低。确定的主要危险因素包括二手烟、颗粒物污染、低出生体重和妊娠期短。此外,SDI与OM负担之间存在显著的负相关,随着SDI的增加,年龄标准化的DALY率显着下降。结论:儿童OM是一项不断升级的全球健康挑战,其特点是发病率不断上升。尽管全球伤残调整生命年有所下降,但与儿童OM相关的伤残调整生命年的负担仍然很大,特别是在SDI较低的地区。更全面地了解儿童OM的流行病学可以加强预防和控制工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Global, regional, and national epidemiology of otitis media in children from 1990 to 2021.

Background: Otitis media(OM) is a prevalent ear condition, particularly among children, with a significant impact on quality of life. This study aimed to elucidate the global prevalence and disability-adjusted life years (DALYs) associated with OM in the 0-14 age group from 1990-2021, using data from the 2021 Global Burden of Disease (GBD) study.

Methods: Our study conducted a comprehensive analysis of OM data from the GBD 2021 report, examining the prevalence and DALYs related to OM across 204 countries and territories over a 32-year period. Data were stratified by age, sex, year, geographic region, and sociodemographic index (SDI). Temporal trends were evaluated using estimated annual percent change (EAPC) calculations. Additionally, a global risk attribution analysis for childhood OM was conducted, and a Bayesian age-period-cohort (BAPC) model was applied to project the global burden of childhood OM from 2021-2035.

Results: In 2021, the global burden of OM in children remained significant, with an incidence of 297,243,470 cases and an age-standardized prevalence of 14,775 cases per 100,000 population. OM resulted in 1,035,749 DALYs globally, with an age-standardized DALY rate of 51.48 per 100,000 population. Regionally, the highest age-standardized prevalence of OM was observed in Eastern Sub-Saharan Africa, South Asia, and Western Sub-Saharan Africa, while Central Europe, East Asia, and High-income Asia Pacific exhibited the lowest prevalence. Key risk factors identified include secondhand smoke, particulate matter pollution, low birth weight, and short gestation. Additionally, a significant inverse association was found between the SDI and the burden of OM, with age-standardized DALY rates decreasing markedly as SDI increased.

Conclusion: OM in children represents an escalating global health challenge, marked by a rising incidence. Although there has been a global decline in DALYs, the burden of DALYs associated with OM in children remains significant, particularly in regions with a low SDI. A more comprehensive understanding of the epidemiology of OM in children could enhance prevention and control efforts.

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来源期刊
Frontiers in Pediatrics
Frontiers in Pediatrics Medicine-Pediatrics, Perinatology and Child Health
CiteScore
3.60
自引率
7.70%
发文量
2132
审稿时长
14 weeks
期刊介绍: Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.
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