西尼罗脑炎患者的突发性感音神经性听力损失

IF 1.7 4区 医学 Q2 OTORHINOLARYNGOLOGY
Raj Malhotra, Barrie Schmitt, Ken Tyler, Yuri Agrawal
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引用次数: 0

摘要

目的突发性感音神经性听力损失(SSNHL)是一种常见的疾病,通常是特发性的,但也可能是由感染引起的。由西尼罗河病毒(WNV)引起的神经侵入性疾病是SSNHL的罕见病因,通常影响免疫功能低下的患者,通常与听力恢复最小相关。我们提出了一个免疫功能正常的妇女谁被诊断为SSNHL在设置西尼罗河病毒感染和听力显着改善。方法结合病例报告和文献复习。结果一名55岁免疫功能正常的女性,因失衡加重和新发双侧听力损失多次就诊急诊科后,来到我耳鼻喉科就诊。听力图显示双侧SNHL。在对血液学、肿瘤学、免疫学和感染性病因进行全面的住院评估后,脑脊液和血清中西尼罗河病毒IgG和IgM抗体升高。患者接受保守治疗,在随访中,她的重复听力图显示出明显的听力改善。结论神经侵袭性西尼罗河病毒患者发生SSNHL极为罕见,既往报道病例较少。在美国,特别是在夏末和秋季,西尼罗河病毒应被认为是SSNHL的一个原因。应告知患者听力损失的预后变化,对于深度听力损失没有明显恢复的患者,应尽早讨论人工耳蜗植入。证据等级:四级
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Sudden Sensorineural Hearing Loss in an Immunocompetent Patient With West Nile Encephalitis

Sudden Sensorineural Hearing Loss in an Immunocompetent Patient With West Nile Encephalitis

Objective

Sudden sensorineural hearing loss (SSNHL) is a frequently encountered condition that is often idiopathic but may be precipitated by infection. Neuroinvasive disease resulting from West Nile virus (WNV) is a rare cause of SSNHL, typically affecting immunocompromised patients and generally associated with minimal hearing recovery. We present a case of an immunocompetent woman who was diagnosed with SSNHL in the setting of a WNV infection and showed significant hearing improvement.

Methods

Case report and literature review.

Results

A 55-year-old immunocompetent female presented to our Otolaryngology office after several visits to the emergency department for worsening disequilibrium and new onset bilateral hearing loss. An audiogram demonstrated bilateral SNHL. After a thorough inpatient evaluation for hematologic, oncologic, immunologic, and infectious etiologies, CSF and serum IgG and IgM antibodies to WNV were elevated. The patient was managed conservatively and, at follow-up, endorsed significant hearing improvement that was reflected on her repeat audiogram.

Conclusion

SSNHL in patients with neuroinvasive WNV is extremely rare, with only a small number of previously reported cases. WNV should be considered as a cause of SSNHL in the US, especially during the late summer and fall months. Patients should be counseled on the variable prognosis of the hearing loss, and early discussions regarding cochlear implantation should be pursued for patients without significant recovery of profound hearing loss.

Level of Evidence: IV

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来源期刊
CiteScore
3.00
自引率
0.00%
发文量
245
审稿时长
11 weeks
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