钌三-双齿配合物作为多功能光引发剂的潜力

IF 4.6 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Macromolecular Materials and Engineering Pub Date : 2025-04-09 DOI:10.1002/mame.202400458

Quinn V. C. van Hilst, Vinh Khanh Doan, Bram G Soliman, Yiwei Li, Yi Wang, Siyuan Liu, Kieran Lau, Habib Joukhdar, Qishu He, Chung-Wei (Roy) Hsu, Chun Xu, Jelena Rnjak-Kovacina, Tim B. F. Woodfield, James D. Crowley, Khoon S. Lim

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引用次数: 0

摘要

研究了一种具有光学活性的抗菌钌（II）菲罗啉配合物（三（3,4,7,8-四甲基-1,10-菲罗啉）二氯化钌）作为多功能光引发剂的潜力。抗菌和细胞毒性研究表明，该复合物具有生物活性，并在0.5 mm以下存活。该配合物与三（2,2′-联吡啶基）钌（II）二氯化物类似，在可见光下可光聚合明胶，并在明胶水凝胶制备后保持抗菌活性。将光引发剂掺入混合明胶颗粒支架的间质液中产生多功能支架，该支架保留了细胞活力并表现出可注射特性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The Potential of Ruthenium(II) Tris-Bidentate Complexes as Multifunctional Photo-Initiators

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The Potential of Ruthenium(II) Tris-Bidentate Complexes as Multifunctional Photo-Initiators

An optically active antibacterial ruthenium(II) phenanthroline complex (tris(3,4,7,8-tetramethyl-1,10-phenanthroline) ruthenium(II) dichloride), is investigated for its potential as a multifunctional photo-initiator. Antibacterial and cytotoxic studies indicated that the complex is biologically active, and viable below <0.5 mm. The complex is shown to photo-polymerize gelatin using visible light in a similar manner to tris(2,2′-bipyridyl)ruthenium(II) dichloride and is demonstrated to retain antibacterial activity post-fabrication of a gelatin hydrogel. Incorporation of the photo-initiator into the interstitial fluid of a hybrid gelatin granular scaffold generated a multifunctional scaffold that retained cell viability and exhibited injectable properties.

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来源期刊

Macromolecular Materials and Engineering 工程技术-材料科学：综合

CiteScore

7.30

自引率

5.10%

发文量

328

审稿时长

1.6 months

期刊介绍： Macromolecular Materials and Engineering is the high-quality polymer science journal dedicated to the design, modification, characterization, processing and application of advanced polymeric materials, including membranes, sensors, sustainability, composites, fibers, foams, 3D printing, actuators as well as energy and electronic applications. Macromolecular Materials and Engineering is among the top journals publishing original research in polymer science. The journal presents strictly peer-reviewed Research Articles, Reviews, Perspectives and Comments. ISSN: 1438-7492 (print). 1439-2054 (online). Readership:Polymer scientists, chemists, physicists, materials scientists, engineers Abstracting and Indexing Information: CAS: Chemical Abstracts Service (ACS) CCR Database (Clarivate Analytics) Chemical Abstracts Service/SciFinder (ACS) Chemistry Server Reaction Center (Clarivate Analytics) ChemWeb (ChemIndustry.com) Chimica Database (Elsevier) COMPENDEX (Elsevier) Current Contents: Physical, Chemical & Earth Sciences (Clarivate Analytics) Directory of Open Access Journals (DOAJ) INSPEC (IET) Journal Citation Reports/Science Edition (Clarivate Analytics) Materials Science & Engineering Database (ProQuest) PASCAL Database (INIST/CNRS) Polymer Library (iSmithers RAPRA) Reaction Citation Index (Clarivate Analytics) Science Citation Index (Clarivate Analytics) Science Citation Index Expanded (Clarivate Analytics) SciTech Premium Collection (ProQuest) SCOPUS (Elsevier) Technology Collection (ProQuest) Web of Science (Clarivate Analytics)