牛支原体新型氟喹诺酮类药物耐药突变的出现，中国，2008-2023

IF 6.6 2区医学 Q1 IMMUNOLOGY

Emerging Infectious Diseases Pub Date : 2025-07-16 DOI:10.3201/eid3108.241137

Shimei Lan, Shuang Liu, Wenjing Cui, Zhangcheng Li, Huafang Hao, Ahmed Adel Baz, Jinjia Liang, Xiangrui Jin, Xinmin Yan, Pengcheng Gao, Fuying Zheng, Shengli Chen, Yuefeng Chu

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引用次数: 0

摘要

目的研究2008-2023年在中国分离的牛支原体对喹诺酮类药物的耐药性。序列52型为优势基因型；GyrA （S83F/Y）和ParC （S80R）蛋白双突变引起对氟喹诺酮类药物的高耐药性。需要加强对牛中牛分枝杆菌感染的警惕和监测，以预防疾病。

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Emergence of Novel Fluoroquinolone Resistance Mutations in Mycoplasma bovis, China, 2008–2023

We investigated quinolone resistance in Mycoplasma bovis samples isolated in China during 2008–2023. Sequence type 52 was the dominant genotype; GyrA (S83F/Y) and ParC (S80R) protein double mutations caused high resistance to fluoroquinolones. Increased vigilance and surveillance of M. bovis infections in cattle will be needed to prevent disease.

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来源期刊

Emerging Infectious Diseases 医学-传染病学

CiteScore

17.30

自引率

1.70%

发文量

505

审稿时长

1 months

期刊介绍： Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination. Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.