2008-2021年瑞典1型糖尿病发病率

IF 2.4 4区 医学 Q1 PEDIATRICS
Acta Paediatrica Pub Date : 2025-07-16 DOI:10.1111/apa.70226
Yazan Al Abed, Araz Rawshani, Aidin Rawshani, Björn Eliasson, Mohammad Al Masri, Gustaf Lernfelt, Daniel Novak, Joanna Pestalozzi, Maria Henningsson
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引用次数: 0

摘要

目的:我们分析了2008年至2021年0-24岁人群的1型糖尿病发病率,重点关注发病年龄和COVID-19大流行期间的潜在变化。方法:使用处方药注册表中的胰岛素处方评估1型糖尿病的发病率。一个或多个处方定义了男性病例;女性需要三个或更多。数据按5岁年龄组分层,并在2008年至2021年期间进行分析。结果:与2008-2019年相比,2021年0-24岁人群的1型糖尿病发病率增加了12%。2021年发病率最高的是0-4岁、5-9岁和20-24岁年龄组。10-14岁年龄组的总体肥胖率最高,其次是5-9岁、15-19岁、20-24岁和0-4岁。发病率在大流行前保持稳定,随着时间的推移,发病年龄显著下降。结论:在2008年至2021年间,观察到1型糖尿病发病年龄向年轻化转变。2021年发病率增加可能受到COVID-19大流行期间广泛传播的SARS-CoV-2感染可能产生的延迟效应的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Incidence of Type 1 Diabetes in Sweden During 2008-2021.

Aims: We analysed type 1 diabetes incidence in individuals aged 0-24 years from 2008 to 2021, with a focus on age at onset and potential changes during the COVID-19 pandemic.

Methods: Type 1 diabetes incidence was assessed using insulin prescriptions from the Prescribed Drug Register. One or more prescriptions defined a case in males; three or more were required in females. Data were stratified into 5-year age groups and analysed over the 2008-2021 period.

Results: Type 1 diabetes incidence increased by 12% in individuals aged 0-24 years in 2021 compared to 2008-2019. The highest 2021 incidence was observed in the 0-4, 5-9 and 20-24 age groups. The 10-14 group consistently had the highest rates overall, followed by 5-9, 15-19, 20-24 and 0-4. Incidence was stable prepandemic, and a significant decline in age at onset was observed over time.

Conclusions: A shift in the age of onset of type 1 diabetes towards younger ages was observed between 2008 and 2021. The increased incidence in 2021 could be influenced by a possible delayed effect of the widespread SARS-CoV-2 infections during the COVID-19 pandemic.

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来源期刊
Acta Paediatrica
Acta Paediatrica 医学-小儿科
CiteScore
6.50
自引率
5.30%
发文量
384
审稿时长
2-4 weeks
期刊介绍: Acta Paediatrica is a peer-reviewed monthly journal at the forefront of international pediatric research. It covers both clinical and experimental research in all areas of pediatrics including: neonatal medicine developmental medicine adolescent medicine child health and environment psychosomatic pediatrics child health in developing countries
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