{"title":"鉴别牙源性黏液瘤和成釉细胞瘤的MR图像囊肿样区域。","authors":"Ami Kuribayashi, Shin Nakamura, Hiroshi Watanabe, Sakurako Kawashima, Shinya Kotaki, Akiko Imaizumi, Hiroshi Tomisato, Yoshikazu Nomura, Miharu Taguchi, Arisa Oki, Sakiko Kume, Masahiko Miura","doi":"10.1007/s11282-025-00841-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to identify characteristic findings of odontogenic myxoma (OM) and assess the role of MRI in differentiating OM from ameloblastoma by analysing cyst-like areas.</p><p><strong>Methods: </strong>MRI images from 12 and 15 patients with OM and ameloblastoma, respectively, were retrospectively evaluated to determine imaging features useful for differentiation. We analysed cyst-like areas in OM using apparent diffusion coefficient (ADC) values and gadolinium contrast patterns, comparing them with those in ameloblastoma. ADC values were statistically assessed via the Mann-Whitney U test.</p><p><strong>Results: </strong>In OM, the mean ADC value of cyst-like areas was 1.84 × 10⁻<sup>3</sup> mm<sup>2</sup>/s. Contrast-enhanced T1-weighted images showed signal enhancement, with a gradual increase on dynamic contrast-enhanced MRI (DCE-MRI). Conversely, in ameloblastoma, the mean ADC value was 2.28 × 10⁻<sup>3</sup> mm<sup>2</sup>/s. Unlike OM, its cyst-like areas lacked enhancement, with only the solid areas exhibiting a rapid signal increase on DCE-MRI. ADC values were significantly higher in ameloblastoma (P < 0.05).</p><p><strong>Conclusions: </strong>The presence or absence of contrast enhancement in cyst-like areas aids in differentiating OM from ameloblastoma. Additionally, ADC values may be used to differentiate between these tumors in the absence of contrast agents.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Differentiating odontogenic myxoma from ameloblastoma by focusing on cyst-like areas on MR images.\",\"authors\":\"Ami Kuribayashi, Shin Nakamura, Hiroshi Watanabe, Sakurako Kawashima, Shinya Kotaki, Akiko Imaizumi, Hiroshi Tomisato, Yoshikazu Nomura, Miharu Taguchi, Arisa Oki, Sakiko Kume, Masahiko Miura\",\"doi\":\"10.1007/s11282-025-00841-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>This study aimed to identify characteristic findings of odontogenic myxoma (OM) and assess the role of MRI in differentiating OM from ameloblastoma by analysing cyst-like areas.</p><p><strong>Methods: </strong>MRI images from 12 and 15 patients with OM and ameloblastoma, respectively, were retrospectively evaluated to determine imaging features useful for differentiation. We analysed cyst-like areas in OM using apparent diffusion coefficient (ADC) values and gadolinium contrast patterns, comparing them with those in ameloblastoma. ADC values were statistically assessed via the Mann-Whitney U test.</p><p><strong>Results: </strong>In OM, the mean ADC value of cyst-like areas was 1.84 × 10⁻<sup>3</sup> mm<sup>2</sup>/s. Contrast-enhanced T1-weighted images showed signal enhancement, with a gradual increase on dynamic contrast-enhanced MRI (DCE-MRI). Conversely, in ameloblastoma, the mean ADC value was 2.28 × 10⁻<sup>3</sup> mm<sup>2</sup>/s. Unlike OM, its cyst-like areas lacked enhancement, with only the solid areas exhibiting a rapid signal increase on DCE-MRI. ADC values were significantly higher in ameloblastoma (P < 0.05).</p><p><strong>Conclusions: </strong>The presence or absence of contrast enhancement in cyst-like areas aids in differentiating OM from ameloblastoma. Additionally, ADC values may be used to differentiate between these tumors in the absence of contrast agents.</p>\",\"PeriodicalId\":56103,\"journal\":{\"name\":\"Oral Radiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-07-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oral Radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s11282-025-00841-2\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11282-025-00841-2","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Differentiating odontogenic myxoma from ameloblastoma by focusing on cyst-like areas on MR images.
Objectives: This study aimed to identify characteristic findings of odontogenic myxoma (OM) and assess the role of MRI in differentiating OM from ameloblastoma by analysing cyst-like areas.
Methods: MRI images from 12 and 15 patients with OM and ameloblastoma, respectively, were retrospectively evaluated to determine imaging features useful for differentiation. We analysed cyst-like areas in OM using apparent diffusion coefficient (ADC) values and gadolinium contrast patterns, comparing them with those in ameloblastoma. ADC values were statistically assessed via the Mann-Whitney U test.
Results: In OM, the mean ADC value of cyst-like areas was 1.84 × 10⁻3 mm2/s. Contrast-enhanced T1-weighted images showed signal enhancement, with a gradual increase on dynamic contrast-enhanced MRI (DCE-MRI). Conversely, in ameloblastoma, the mean ADC value was 2.28 × 10⁻3 mm2/s. Unlike OM, its cyst-like areas lacked enhancement, with only the solid areas exhibiting a rapid signal increase on DCE-MRI. ADC values were significantly higher in ameloblastoma (P < 0.05).
Conclusions: The presence or absence of contrast enhancement in cyst-like areas aids in differentiating OM from ameloblastoma. Additionally, ADC values may be used to differentiate between these tumors in the absence of contrast agents.
期刊介绍：
As the official English-language journal of the Japanese Society for Oral and Maxillofacial Radiology and the Asian Academy of Oral and Maxillofacial Radiology, Oral Radiology is intended to be a forum for international collaboration in head and neck diagnostic imaging and all related fields. Oral Radiology features cutting-edge research papers, review articles, case reports, and technical notes from both the clinical and experimental fields. As membership in the Society is not a prerequisite, contributions are welcome from researchers and clinicians worldwide.
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