Namie Okino Sawada, Tiago Marques Dos Reis, Patrícia Scotini Freitas, Camila Mendonça de Moraes, Bianca de Moura Peloso-Carvalho, Munyra Rocha Silva Assunção, Camila Maria Silva Paraizo Horvath, Ranile Santos Silva, Karina Dal Sasso Mendes
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引用次数: 0
摘要
确定危重患者中COVID-19全身性并发症的患病率，估计与COVID-19相关的可能导致预后更差的临床状况。基于JBI证据综合手册对2020年至2024年期间6个数据库和灰色文献的患病率和发病率系统评价的建议，对观察性研究进行meta分析的系统评价，语言为葡萄牙语、英语和西班牙语。我们确定了2393份出版物。研究的选择、数据提取和方法学评价由两名独立研究人员进行。meta分析采用Freeman Tukey转换随机效应统计方法。共收录了10篇论文。对7篇涉及COVID-19呼吸道并发症的论文的荟萃分析显示，平均患病率为42% (95% CI 0.2-0.66)，异质性I2=97.4；对4篇涉及COVID-19神经系统并发症患病率的论文的荟萃分析显示，平均患病率为62%，（95% CI 0.49- 0.74），异质性I2=87.4；对8项研究的荟萃分析显示，COVID-19死亡率患病率为33%，（95% CI 0.23- 0.44），异质性I2=93.6。在回顾的研究中，呼吸系统和神经系统并发症最为普遍。普洛斯彼罗注册号：CRD42020214617。
Prevalence of systemic complications of COVID-19 in critically ill patients: systematic review with meta-analysis.
to identify the prevalence of systemic complications of COVID-19 in critically ill patients, to estimate the clinical conditions that may have a worse prognosis when associated with COVID-19.
systematic review with meta-analysis of observational studies, based on the recommendations of the JBI Manual for Evidence Synthesis for systematic reviews of prevalence and incidence, in six databases and grey literature, period 2020 to 2024, languages Portuguese, English and Spanish. We identified 2393 publications. The selection, data extraction and methodological evaluation of the studies were carried out by two independent researchers. The meta-analysis was performed using the Freeman Tukey transformational random-effects statistical method.
ten papers were included. The meta-analysis of seven papers dealing with respiratory complications due to COVID-19 demonstrated a mean prevalence of 42%, (95% CI 0.2-0.66) with heterogeneity I2=97.4; the meta-analysis of 4 papers involving the prevalence of neurological complications due to COVID-19 showed an average prevalence of 62%, (95% CI 0.49- 0.74) with heterogeneity I2=87.4 and the meta-analysis of 8 studies showed a prevalence of mortality due to COVID-19 of 33%, (95% CI 0.23- 0.44) with heterogeneity I2=93.6.
respiratory and neurological complications were the most prevalent in the reviewed studies. PROSPERO Registration: CRD42020214617.
期刊介绍：
A Revista Latino-Americana de Enfermagem constitui-se no órgão oficial de divulgação científica da Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo e do Centro Colaborador da OMS para o Desenvolvimento da Pesquisa em Enfermagem. Foi criada em abril de 1992 sendo sua primeira edição publicada em janeiro de 1993. No período de 1993 a 1997 tinha periodicidade semestral, de 1997 a 2000 trimestral e, a partir de janeiro de 2001, tem periodicidade bimestral.
Caracteriza-se como periódico de circulação internacional, abrangendo predominantemente os países da América Latina e Caribe, embora seja também divulgado para assinantes dos Estados Unidos, Portugal e Espanha.
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