Zhaozhao Chen,Lan-Lin Chiou,Javier Calatrava,Hom-Lay Wang
{"title":"抗生素在预防牙周病和种植牙科手术并发症中的作用。","authors":"Zhaozhao Chen,Lan-Lin Chiou,Javier Calatrava,Hom-Lay Wang","doi":"10.1111/prd.12636","DOIUrl":null,"url":null,"abstract":"Antibiotics are commonly prescribed in periodontal and implant surgeries, either before, during or after surgery, to prevent postoperative infection and reduce early implant failure. However, the potential benefits may be undermined by the risks of resistance and sensitization, thus requiring a strict indication for prescription. There are controversial views regarding the indication, dosage, duration, and timing of antibiotic medication in periodontal and implant surgery. Therefore, the aim of this review is to address the benefits and concerns regarding the efficacy of using preventive antibiotic therapy in Periodontology and Implant Dentistry. Specifically, various types of procedures were comprehensively explored, and recommendations were given accordingly. The available evidence indicates that preventive antibiotic therapy is not warranted for periodontal surgeries, including conventional, plastic, and regenerative procedures. While antibiotic prophylaxis has shown effectiveness in preventing early implant failures in straightforward implant placements, postoperative coverage does not appear to be justified. Furthermore, antibiotic administration has not proven to significantly reduce early implant failure rates in implant placements involving simultaneous guided bone regeneration. There remains insufficient evidence to support or oppose the use of preventive antibiotic therapy for reducing infection rates after ridge or sinus augmentation procedures, nor is there evidence favoring any specific protocol over others.","PeriodicalId":19736,"journal":{"name":"Periodontology 2000","volume":"10 1","pages":""},"PeriodicalIF":15.7000,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The role of antibiotics in preventing surgical complications in periodontology and implant dentistry.\",\"authors\":\"Zhaozhao Chen,Lan-Lin Chiou,Javier Calatrava,Hom-Lay Wang\",\"doi\":\"10.1111/prd.12636\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Antibiotics are commonly prescribed in periodontal and implant surgeries, either before, during or after surgery, to prevent postoperative infection and reduce early implant failure. However, the potential benefits may be undermined by the risks of resistance and sensitization, thus requiring a strict indication for prescription. There are controversial views regarding the indication, dosage, duration, and timing of antibiotic medication in periodontal and implant surgery. Therefore, the aim of this review is to address the benefits and concerns regarding the efficacy of using preventive antibiotic therapy in Periodontology and Implant Dentistry. Specifically, various types of procedures were comprehensively explored, and recommendations were given accordingly. The available evidence indicates that preventive antibiotic therapy is not warranted for periodontal surgeries, including conventional, plastic, and regenerative procedures. While antibiotic prophylaxis has shown effectiveness in preventing early implant failures in straightforward implant placements, postoperative coverage does not appear to be justified. Furthermore, antibiotic administration has not proven to significantly reduce early implant failure rates in implant placements involving simultaneous guided bone regeneration. There remains insufficient evidence to support or oppose the use of preventive antibiotic therapy for reducing infection rates after ridge or sinus augmentation procedures, nor is there evidence favoring any specific protocol over others.\",\"PeriodicalId\":19736,\"journal\":{\"name\":\"Periodontology 2000\",\"volume\":\"10 1\",\"pages\":\"\"},\"PeriodicalIF\":15.7000,\"publicationDate\":\"2025-07-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Periodontology 2000\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/prd.12636\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Periodontology 2000","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/prd.12636","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
The role of antibiotics in preventing surgical complications in periodontology and implant dentistry.
Antibiotics are commonly prescribed in periodontal and implant surgeries, either before, during or after surgery, to prevent postoperative infection and reduce early implant failure. However, the potential benefits may be undermined by the risks of resistance and sensitization, thus requiring a strict indication for prescription. There are controversial views regarding the indication, dosage, duration, and timing of antibiotic medication in periodontal and implant surgery. Therefore, the aim of this review is to address the benefits and concerns regarding the efficacy of using preventive antibiotic therapy in Periodontology and Implant Dentistry. Specifically, various types of procedures were comprehensively explored, and recommendations were given accordingly. The available evidence indicates that preventive antibiotic therapy is not warranted for periodontal surgeries, including conventional, plastic, and regenerative procedures. While antibiotic prophylaxis has shown effectiveness in preventing early implant failures in straightforward implant placements, postoperative coverage does not appear to be justified. Furthermore, antibiotic administration has not proven to significantly reduce early implant failure rates in implant placements involving simultaneous guided bone regeneration. There remains insufficient evidence to support or oppose the use of preventive antibiotic therapy for reducing infection rates after ridge or sinus augmentation procedures, nor is there evidence favoring any specific protocol over others.
期刊介绍:
Periodontology 2000 is a series of monographs designed for periodontists and general practitioners interested in periodontics. The editorial board selects significant topics and distinguished scientists and clinicians for each monograph. Serving as a valuable supplement to existing periodontal journals, three monographs are published annually, contributing specialized insights to the field.