17岁抗磷脂综合征伴肺栓塞、脑静脉窦和心脏血栓。

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Pulmonology Pub Date : 2025-07-01 DOI:10.1002/ppul.71202

Muhammed Tekinhatun, Mehmet Sait Duyu

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引用次数: 0

摘要

一名17岁男孩最初表现为晕厥、发烧、头痛和呕吐。检查发现颈部僵硬和双侧乳头水肿。影像学发现上矢状窦和左横窦血栓形成。一年后，他出现胸痛、癫痫发作和双侧肺栓塞，超声心动图显示心内血栓。手术切除证实为纤维性血栓。尽管抗凝治疗，反复发生心内血栓和肺出血。血栓病检查证实抗磷脂综合征（APS）。这个罕见的病例强调了aps相关的多系统血栓事件和心内血栓在儿科患者中的作用，强调了影像学在早期诊断中的作用。

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Antiphospholipid Syndrome With Pulmonary Embolism, Cerebral Venous Sinus and Cardiac Thrombosis in a 17-Year-Old.

A 17-year-old boy initially presented with syncope, fever, headache, and vomiting. Examination revealed neck stiffness and bilateral papilledema. Imaging identified superior sagittal and left transverse sinus thrombosis. One year later, he developed chest pain, seizures, and bilateral pulmonary emboli, with chocardiography demonstrated intracardiac thrombi. Surgical excision confirmed fibrinous thrombi. Despite anticoagulation, recurrent intracardiac thrombi and pulmonary hemorrhage occurred. Thrombophilia workup confirmed antiphospholipid syndrome (APS). This rare case highlights APS-related multisystemic thrombotic events and intracardiac thrombi in a pediatric patient, emphasizing the role of imaging in early diagnosis.

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来源期刊

Pediatric Pulmonology 医学-呼吸系统

CiteScore

6.00

自引率

12.90%

发文量

468

审稿时长

3-8 weeks

期刊介绍： Pediatric Pulmonology (PPUL) is the foremost global journal studying the respiratory system in disease and in health as it develops from intrauterine life though adolescence to adulthood. Combining explicit and informative analysis of clinical as well as basic scientific research, PPUL provides a look at the many facets of respiratory system disorders in infants and children, ranging from pathological anatomy, developmental issues, and pathophysiology to infectious disease, asthma, cystic fibrosis, and airborne toxins. Focused attention is given to the reporting of diagnostic and therapeutic methods for neonates, preschool children, and adolescents, the enduring effects of childhood respiratory diseases, and newly described infectious diseases. PPUL concentrates on subject matters of crucial interest to specialists preparing for the Pediatric Subspecialty Examinations in the United States and other countries. With its attentive coverage and extensive clinical data, this journal is a principle source for pediatricians in practice and in training and a must have for all pediatric pulmonologists.