封面特写:在铁酚二茂铁基团上引入磷化氢基团开辟了具有抗癌活性的新型杂双金属配合物的途径(ChemistryEurope 4/2025)

ChemistryEurope Pub Date : 2025-07-16 DOI:10.1002/ceur.70008
Magda Křelinová, Michèle Salmain, Petr Štěpnička, Ivana Císařová, Benoît Bertrand, Jiří Schulz
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引用次数: 0

摘要

封面特征显示了一种新的二铁酚衍生物,该衍生物被设计用于为一种突出的有机金属抗癌剂配备额外的磷化氢基团,能够协调其他金属中心。在他们的研究文章(DOI: 10.1002/ceur.202500048)中,B. Bertrand, J. Schulz和同事报告了这种化合物的合成,其相应的磷盐,以及包含功能磷化氢的过渡金属配合物,以及它们作为抗癌剂的初步评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Cover Feature: Introduction of a Phosphine Group onto the Ferrocene Moiety in Ferrociphenol Opens Access to New Heterobimetallic Complexes with Anticancer Activity (ChemistryEurope 4/2025)

Cover Feature: Introduction of a Phosphine Group onto the Ferrocene Moiety in Ferrociphenol Opens Access to New Heterobimetallic Complexes with Anticancer Activity (ChemistryEurope 4/2025)

The Cover Feature shows a new ferrociphenol derivative that was designed to equip a prominent organometallic anticancer agent with an additional phosphine group capable of coordinating other metal centers. In their Research Article (DOI: 10.1002/ceur.202500048), B. Bertrand, J. Schulz and co-workers report the syntheses of this compound, its corresponding phosphonium salt, and transition metal complexes incorporating the functional phosphine, along with their preliminary evaluation as anticancer agents.

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