Kazim Kerim Moncal, Laeya Abdoli Najmi, Rakhi Gupta, Malavika Ramarao, Joshua W. Knowles, Chong Y. Park, Naside Gozde Durmus
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Label-Free Detection of Lipid Accumulation in Cells Using Magnetic Levitation (Adv. Biology 7/2025)
Label-Free Detection of Lipid Accumulation via Magnetic Levitation
Magnetic levitation can be used for label-free profiling and characterization of lipid accumulation within cells, by separating cells based on their biophysical profiles. As pre-adipocytes differentiate, lipid accumulation occurs, leading to lower cell density and higher levitation heights. Four distinct layers can be seen within the magnetic levitation device: lipid vesicles (at top), mature adipocytes, adipocytes, and pre-adipocytes. More details can be found in article number 2200142 by Naside Gozde Durmus and co-workers.
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