小的细胞外囊泡封装到聚乙二醇化金属-酚网络的选择性可拆卸外壳中（Adv. Healthcare Mater. 18/2025）

IF 10 2区医学 Q1 ENGINEERING, BIOMEDICAL

Advanced Healthcare Materials Pub Date : 2025-07-16 DOI:10.1002/adhm.202570109

Chenyu Wang, Ailifeire Fulati, Kenta Kimura, Xianglan Li, Joseph J. Richardson, Mitsuru Naito, Kanjiro Miyata, Takanori Ichiki, Hirotaka Ejima

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引用次数: 0

摘要

小细胞外囊泡：在文章2405188中，Hirotaka Ejima及其同事介绍了一种选择性可拆卸的小细胞外囊泡（sev）表面修饰方法，该方法利用聚乙二醇后修饰金属-酚网络。这种纳米涂层显著提高了sev的储存稳定性，并允许选择性地触发封装壳的拆卸，以恢复完整和功能的sev，从而促进高效的储存、运输和随后有前景的生物医学应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal-Phenolic Networks (Adv. Healthcare Mater. 18/2025)

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Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal-Phenolic Networks (Adv. Healthcare Mater. 18/2025)

Small Extracellular Vesicles

In article 2405188, Hirotaka Ejima and co-workers introduce a selectively disassemblable surface modification approach for small extracellular vesicles (sEVs) utilizing metal-phenolic networks that post-modified with polyethylene glycol. Such nanocoating significantly enhances the storage stability of sEVs and allows selectively triggered disassembly of encapsulated shells for the retrieval of intact and functional sEVs, thereby facilitating efficient storage, transport and subsequent promising biomedical applications.

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来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.