儿童原发性肾内卵黄囊肿瘤：1例报告并总结先前发表的病例。

IF 0.7 4区医学 Q4 PATHOLOGY

Fetal and Pediatric Pathology Pub Date : 2025-07-14 DOI:10.1080/15513815.2025.2532578

Oindrila Das, Raktim Mukherjee, Debalina Karmakar, Kalyani Saha Basu, Uttara Chatterjee

{"title":"儿童原发性肾内卵黄囊肿瘤：1例报告并总结先前发表的病例。","authors":"Oindrila Das, Raktim Mukherjee, Debalina Karmakar, Kalyani Saha Basu, Uttara Chatterjee","doi":"10.1080/15513815.2025.2532578","DOIUrl":null,"url":null,"abstract":"Background: Renal tumors are common primary tumors in children with Wilms tumor being the most prevalent one. Others include clear cell sarcoma kidney, congenital mesoblastic nephroma and rhabdoid tumors. Extragonadal germ cell tumors especially primary intrarenal yolk sac tumor (YST) is extremely uncommon. Only 6 cases of primary intrarenal YST have been reported so far.Case report: A 2-year-old boy presented with a left sided abdominal mass. Imaging studies were consistent with Wilms tumor. He received chemotherapy followed by nephrectomy. Histopathological examination revealed a primary intrarenal yolk sac tumor.Conclusion: This case report emphasizes the need to include germ cell tumors, particularly YSTs, in the differential diagnosis of pediatric renal tumors.","PeriodicalId":50452,"journal":{"name":"Fetal and Pediatric Pathology","volume":" ","pages":"1-7"},"PeriodicalIF":0.7000,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Primary Intrarenal Yolk Sac Tumor in a Child: A Case Report with Summary of Prior Published Cases.\",\"authors\":\"Oindrila Das, Raktim Mukherjee, Debalina Karmakar, Kalyani Saha Basu, Uttara Chatterjee\",\"doi\":\"10.1080/15513815.2025.2532578\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Renal tumors are common primary tumors in children with Wilms tumor being the most prevalent one. Others include clear cell sarcoma kidney, congenital mesoblastic nephroma and rhabdoid tumors. Extragonadal germ cell tumors especially primary intrarenal yolk sac tumor (YST) is extremely uncommon. Only 6 cases of primary intrarenal YST have been reported so far.Case report: A 2-year-old boy presented with a left sided abdominal mass. Imaging studies were consistent with Wilms tumor. He received chemotherapy followed by nephrectomy. Histopathological examination revealed a primary intrarenal yolk sac tumor.Conclusion: This case report emphasizes the need to include germ cell tumors, particularly YSTs, in the differential diagnosis of pediatric renal tumors.\",\"PeriodicalId\":50452,\"journal\":{\"name\":\"Fetal and Pediatric Pathology\",\"volume\":\" \",\"pages\":\"1-7\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-07-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Fetal and Pediatric Pathology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/15513815.2025.2532578\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PATHOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fetal and Pediatric Pathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/15513815.2025.2532578","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PATHOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

背景：肾脏肿瘤是儿童常见的原发肿瘤，以肾母细胞瘤最为常见。其他包括肾透明细胞肉瘤、先天性间母细胞肾瘤和横纹肌瘤。生殖道外生殖细胞瘤，尤其是原发性肾内卵黄囊瘤（YST）极为罕见。迄今为止，仅报道了6例原发性肾内囊肿。病例报告：一名2岁男童表现为左侧腹部肿块。影像学检查与Wilms肿瘤一致。他接受了化疗和肾切除术。组织病理学检查显示原发性肾内卵黄囊肿瘤。结论：本病例报告强调需要将生殖细胞肿瘤，特别是囊肿，纳入儿童肾脏肿瘤的鉴别诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Primary Intrarenal Yolk Sac Tumor in a Child: A Case Report with Summary of Prior Published Cases.

Background: Renal tumors are common primary tumors in children with Wilms tumor being the most prevalent one. Others include clear cell sarcoma kidney, congenital mesoblastic nephroma and rhabdoid tumors. Extragonadal germ cell tumors especially primary intrarenal yolk sac tumor (YST) is extremely uncommon. Only 6 cases of primary intrarenal YST have been reported so far.

Case report: A 2-year-old boy presented with a left sided abdominal mass. Imaging studies were consistent with Wilms tumor. He received chemotherapy followed by nephrectomy. Histopathological examination revealed a primary intrarenal yolk sac tumor.

Conclusion: This case report emphasizes the need to include germ cell tumors, particularly YSTs, in the differential diagnosis of pediatric renal tumors.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Fetal and Pediatric Pathology 医学-病理学

CiteScore

3.00

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Fetal and Pediatric Pathology is an established bimonthly international journal that publishes data on diseases of the developing embryo, newborns, children, and adolescents. The journal publishes original and review articles and reportable case reports. The expanded scope of the journal encompasses molecular basis of genetic disorders; molecular basis of diseases that lead to implantation failures; molecular basis of abnormal placentation; placentology and molecular basis of habitual abortion; intrauterine development and molecular basis of embryonic death; pathogenisis and etiologic factors involved in sudden infant death syndrome; the underlying molecular basis, and pathogenesis of diseases that lead to morbidity and mortality in newborns; prenatal, perinatal, and pediatric diseases and molecular basis of diseases of childhood including solid tumors and tumors of the hematopoietic system; and experimental and molecular pathology.