在线执行功能测试:评估验证研究。

IF 2 Q3 HEALTH CARE SCIENCES & SERVICES
Mouna Attarha, Ana Carolina de Figueiredo Pelegrino, Lydia Ouellet, Sarah-Jane Grant, Etienne de Villers-Sidani, Thomas Van Vleet
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引用次数: 0

摘要

背景:执行功能包括一系列高阶认知过程,包括计划、认知灵活性和抑制控制,它们对目标导向行为至关重要。这些能力受到年龄的不利影响,执行功能障碍最终会损害日常生活活动的表现。目的:本研究旨在评估计算机认知评估在预测健康老年人执行功能表现方面的有效性。方法:本回顾性分析利用了通过基于神经可塑性的计算机化锻炼(enhance)试验改善老年人神经系统健康的基线数据。该研究为认知健康的老年人(65岁及以上)提供了规范性数据,并评估了BrainHQ平台上的认知评估“冻结帧”的可用性和有效性。使用美国国立卫生研究院执行能力:神经行为评估和研究的测量和工具(NIH EXAMINER)的执行功能的标准化测量,分析了冻结帧的表现与自我报告的人口统计学变量和神经心理功能的关系。结果:意向治疗分析纳入92例认知健康老年人(平均年龄71.9岁,SD 4.86,范围65 ~ 83岁),其中66%(61/92)为女性,平均文化程度16.45岁(SD 3.40,范围9 ~ 27岁)。在冻结帧上的表现与NIH考官的执行功能得分有适度的相关性(P= 0.02),占方差的6.8%。评估结果显示,年龄(ρ=-0.22, P= 0.046)和性别之间存在较小但有统计学意义的关系,受教育程度没有显著影响。心理测量评估支持其可用性,平均完成时间为4分钟(SD 0.16)。结论:冻结帧是一个简短的,可扩展的,可访问的计算机认知评估,具有执行功能的并发有效性。它在互联网连接设备上的效率和易于管理表明了认知筛查的潜在应用。未来的研究应该探索它在检测临床人群执行功能障碍方面的应用,以及它在预测日常生活活动中的功能表现方面的潜在作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bringing Executive Function Testing Online: Assessment Validation Study.

Background: Executive function encompasses a set of higher-order cognitive processes, including planning, cognitive flexibility, and inhibitory control, that are essential for goal-directed behavior. These abilities are adversely affected by age, with executive dysfunction ultimately impairing the performance of activities of daily living.

Objective: This study aimed to assess the validity of a computerized cognitive assessment in predicting executive function performance in healthy older adults.

Methods: This retrospective analysis utilized baseline data from the Improving Neurological Health in Aging via Neuroplasticity-Based Computerized Exercise (INHANCE) trial. The study provides normative data for cognitively healthy older adults (aged 65 years and above) and evaluates the usability and validity of Freeze Frame, a cognitive assessment available on the BrainHQ platform. Performance on Freeze Frame was analyzed in relation to self-reported demographic variables and neuropsychological function, using a standardized measure of executive function, the National Institutes of Health Executive Abilities: Measures and Instruments for Neurobehavioral Evaluation and Research (NIH EXAMINER).

Results: The intent-to-treat analysis included 92 cognitively healthy older adults (mean age 71.9, SD 4.86, range: 65-83 years), of whom 66% (61/92) were female, with a mean education level of 16.45 (SD 3.40, range: 9-27) years. Performance on Freeze Frame was modestly associated with executive function scores on NIH EXAMINER (P=.02), accounting for 6.8% of the variance. The assessment showed a small but statistically significant relationship to age (ρ=-0.22, P=.046) and gender, with no significant influence of education. Psychometric evaluation supported its usability, with an average completion time of 4 (SD 0.16) minutes.

Conclusions: Freeze Frame is a brief, scalable, and accessible computerized cognitive assessment with demonstrated concurrent validity for executive function. Its efficiency and ease of administration across internet-connected devices suggests potential applications for cognitive screening. Future research should explore its utility in detecting executive dysfunction in clinical populations and its potential role in predicting functional performance across activities of daily living.

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来源期刊
JMIR Formative Research
JMIR Formative Research Medicine-Medicine (miscellaneous)
CiteScore
2.70
自引率
9.10%
发文量
579
审稿时长
12 weeks
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