钙化性肌坏死:罕见临床表现1例并文献复习。

IF 1.1 4区 医学 Q3 ORTHOPEDICS
Indian Journal of Orthopaedics Pub Date : 2025-06-04 eCollection Date: 2025-07-01 DOI:10.1007/s43465-025-01428-z
Vikas Maheshwari, Danish V, Vikas Olkha, Mohit Dhingra, Cury Sharma, Anil Regmi
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引用次数: 0

摘要

简介和重要性:钙化性肌坏死是一种罕见的实体,其特征是凝固性和液化性坏死,累及的筋膜间室的整个肌肉块钙化,继发于创伤后筋膜间室综合征。有有限的文献罕见的疾病与技术困难和陷阱的手术程序在这些患者。病例介绍:一名52岁男性,在手术干预后的过去2年里,他的右腿肿胀并有排出性鼻窦。根据病史和临床-放射-组织学相关性,诊断为钙化性肌坏死病例,并通过真空辅助封闭(VAC)伤口整体切除成功治疗。临床讨论:一种罕见的肌肉骨骼疾病,其特征是肢体间室的肌肉坏死和广泛的钙化,典型的是创伤后筋膜室综合征,涉及肌肉和神经血管结构。诊断在很大程度上依赖于影像学表现,如钙化和邻近骨糜烂,而组织病理学对排除恶性肿瘤至关重要。高的临床怀疑指数对于及时识别至关重要。结论:钙化性肌坏死需要多因素诊断,排除鉴别,合理的术前规划是成功的关键。如果没有感染,这是一种“不要碰我”的疾病;然而,对于感染病例,应考虑通过清创或腔室肿块切除与真空治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Calcific Myonecrosis: Case Report of a Rare Clinical Presentation and Literature Review.

Introduction and importance: Calcific myonecrosis is a rare entity characterized by coagulative and liquefactive necrosis with calcifications of the entire muscle mass of the involved compartment secondary to post-traumatic compartment syndrome. There is limited literature on the rare disease with technical difficulties and pitfalls of operative procedures in these patients.

Presentation of case: A 52-year-old male presented with complaints of swelling over his right leg with discharging sinus over the past 2 years following a surgical intervention. He was diagnosed as a case of calcific myonecrosis based on history and clinico-radio-histological correlation and was managed successfully with en bloc excision with vacuum-assisted closure (VAC) of wound.

Clinical discussion: A rare musculoskeletal condition is characterized by muscle necrosis and extensive calcification within a limb compartment, typically following post-traumatic compartment syndrome involving muscle and neurovascular structures. Diagnosis relies heavily on radiological findings, such as calcifications and adjacent bone erosions, while histopathology is crucial to exclude malignancy. A high index of clinical suspicion is essential for timely identification.

Conclusion: Calcific myonecrosis requires a multi-factorial approach to reach to a diagnosis, with ruling out the differentials and proper preoperative plan are the key to success. If un-infected, it is a "Touch me not disease"; however, through debridement or en-mass excision of compartment with VAC therapy should be considered for infected cases.

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来源期刊
CiteScore
1.80
自引率
0.00%
发文量
185
审稿时长
9 months
期刊介绍: IJO welcomes articles that contribute to Orthopaedic knowledge from India and overseas. We publish articles dealing with clinical orthopaedics and basic research in orthopaedic surgery. Articles are accepted only for exclusive publication in the Indian Journal of Orthopaedics. Previously published articles, articles which are in peer-reviewed electronic publications in other journals, are not accepted by the Journal. Published articles and illustrations become the property of the Journal. The copyright remains with the journal. Studies must be carried out in accordance with World Medical Association Declaration of Helsinki.
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