{"title":"气候变化时期的早孕：妊娠早期热暴露与妊娠第12 /13周胎儿冠臀长度减少有关——奥地利维也纳的一项回顾性研究","authors":"S. Nindl, B. Hartmann, J. Fellner, S. Kirchengast","doi":"10.1002/ajhb.70107","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objectives</h3>\n \n <p>This study focused on the association between fetal crown-rump length (CRL) in the 12th/13th gestational week and the number of 1st trimester heat days to assess the impact of rising temperature on intrauterine growth in early pregnancy.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>This single-center medical record-based study comprises 10 085 singleton live births (<i>n</i><sub>male</sub> = 5228; <i>n</i><sub>female</sub> = 4857) taking place in Vienna, Austria between 2011 and 2019. The sonographic determination of CRL took place routinely during the 12th or 13th gestational week. Linear regression analyses with CRL as the dependent variable and the number of 1st trimester heat days controlled for maternal parameters and the gestational week of CRL measurement were computed for the entire sample and separately by sex.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>CRL decreased significantly (<i>p</i> < 0.001) by 0,015 mm on average per heat day in the 1st trimester. Among male fetuses, CRL decreased significantly (<i>p</i> < 0.001) by 0,021 mm, while among female fetuses, only an insignificant decrease was observed.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Heat days during the 1st trimester could have a small adverse effect on early fetal growth.</p>\n </section>\n </div>","PeriodicalId":50809,"journal":{"name":"American Journal of Human Biology","volume":"37 7","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ajhb.70107","citationCount":"0","resultStr":"{\"title\":\"Early Pregnancy in Times of Climate Change: First-Trimester Heat Exposure Is Associated With Reduction in Fetal Crown-Rump Length in the 12th/13th Week of Gestation—A Retrospective Study From Vienna, Austria\",\"authors\":\"S. Nindl, B. Hartmann, J. Fellner, S. Kirchengast\",\"doi\":\"10.1002/ajhb.70107\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>This study focused on the association between fetal crown-rump length (CRL) in the 12th/13th gestational week and the number of 1st trimester heat days to assess the impact of rising temperature on intrauterine growth in early pregnancy.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>This single-center medical record-based study comprises 10 085 singleton live births (<i>n</i><sub>male</sub> = 5228; <i>n</i><sub>female</sub> = 4857) taking place in Vienna, Austria between 2011 and 2019. The sonographic determination of CRL took place routinely during the 12th or 13th gestational week. Linear regression analyses with CRL as the dependent variable and the number of 1st trimester heat days controlled for maternal parameters and the gestational week of CRL measurement were computed for the entire sample and separately by sex.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>CRL decreased significantly (<i>p</i> < 0.001) by 0,015 mm on average per heat day in the 1st trimester. Among male fetuses, CRL decreased significantly (<i>p</i> < 0.001) by 0,021 mm, while among female fetuses, only an insignificant decrease was observed.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Heat days during the 1st trimester could have a small adverse effect on early fetal growth.</p>\\n </section>\\n </div>\",\"PeriodicalId\":50809,\"journal\":{\"name\":\"American Journal of Human Biology\",\"volume\":\"37 7\",\"pages\":\"\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ajhb.70107\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Human Biology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ajhb.70107\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ANTHROPOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Human Biology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ajhb.70107","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ANTHROPOLOGY","Score":null,"Total":0}
Early Pregnancy in Times of Climate Change: First-Trimester Heat Exposure Is Associated With Reduction in Fetal Crown-Rump Length in the 12th/13th Week of Gestation—A Retrospective Study From Vienna, Austria
Objectives
This study focused on the association between fetal crown-rump length (CRL) in the 12th/13th gestational week and the number of 1st trimester heat days to assess the impact of rising temperature on intrauterine growth in early pregnancy.
Methods
This single-center medical record-based study comprises 10 085 singleton live births (nmale = 5228; nfemale = 4857) taking place in Vienna, Austria between 2011 and 2019. The sonographic determination of CRL took place routinely during the 12th or 13th gestational week. Linear regression analyses with CRL as the dependent variable and the number of 1st trimester heat days controlled for maternal parameters and the gestational week of CRL measurement were computed for the entire sample and separately by sex.
Results
CRL decreased significantly (p < 0.001) by 0,015 mm on average per heat day in the 1st trimester. Among male fetuses, CRL decreased significantly (p < 0.001) by 0,021 mm, while among female fetuses, only an insignificant decrease was observed.
Conclusion
Heat days during the 1st trimester could have a small adverse effect on early fetal growth.
期刊介绍：
The American Journal of Human Biology is the Official Journal of the Human Biology Association.
The American Journal of Human Biology is a bimonthly, peer-reviewed, internationally circulated journal that publishes reports of original research, theoretical articles and timely reviews, and brief communications in the interdisciplinary field of human biology. As the official journal of the Human Biology Association, the Journal also publishes abstracts of research presented at its annual scientific meeting and book reviews relevant to the field.
The Journal seeks scholarly manuscripts that address all aspects of human biology, health, and disease, particularly those that stress comparative, developmental, ecological, or evolutionary perspectives. The transdisciplinary areas covered in the Journal include, but are not limited to, epidemiology, genetic variation, population biology and demography, physiology, anatomy, nutrition, growth and aging, physical performance, physical activity and fitness, ecology, and evolution, along with their interactions. The Journal publishes basic, applied, and methodologically oriented research from all areas, including measurement, analytical techniques and strategies, and computer applications in human biology.
Like many other biologically oriented disciplines, the field of human biology has undergone considerable growth and diversification in recent years, and the expansion of the aims and scope of the Journal is a reflection of this growth and membership diversification.
The Journal is committed to prompt review, and priority publication is given to manuscripts with novel or timely findings, and to manuscripts of unusual interest.
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