绿色合成氧化锌纳米颗粒(ZnO NPs)对鲤鱼生化和组织学特征的影响

IF 1.9 4区 农林科学 Q2 FISHERIES
Hira Asad, Tanveer Ahmed, Huma Naz, Khalid Abbas, Fariha Latif, Saba Suleman, Rana Zeeshan Habib, Zainab Bashir, Muhammad Tayyeb Rizwan, Rashid Iqbal, Ayman A. Swelum
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引用次数: 0

摘要

研究了0.5 mg L−1 (T1)、1 mg L−1 (T2)和2 mg L−1 (T3)氧化锌纳米粒子(ZnO NPs)对鲤血液学、生化和组织学指标的影响。随着氧化锌纳米粒子使用的增加,人们越来越关注其潜在的环境影响,特别是对水生生态系统的影响。当释放到水体中时,这些NPs可被水生生物摄入,导致生物积累和潜在毒性。因此,了解它们对水生物种的影响,如鲤鱼,是至关重要的。发现红细胞计数、血红蛋白(Hb)和红细胞压积(Ht)水平发生显著变化。与对照组相比,锌nps暴露组淋巴细胞、EOSO、单核细胞和血小板数量显著增加。生化分析发现,血液中总蛋白、白蛋白、球蛋白和葡萄糖水平发生了相当大的变化。对鳃、肠和肾进行组织学检查以评估结构或病理改变。处理后的鱼表现出进行性结构扭曲,如坏死(N)、增生(HP)、肥大(HT)、鳃片融合(FGL)和鳃黏液细胞(PM)的增殖。氧化锌NPs处理后鲤鱼肠道细胞间隙(DIS)增大,黏液细胞(IMC)率升高,绒毛萎缩(VA), HP和发育不良(DP)。观察到氧化锌NPs处理的鲤鱼肾脏出现小管扩张、小管坏死、严重充血、造血组织降解、管腔收缩、肾小球病变和鲍曼斯胶囊稀释。本研究结果揭示了ZnO NPs对鲤鱼的生化和组织学影响,有助于更好地了解水生环境中NP暴露的潜在风险。研究结果突出表明,有必要对这些NPs的使用和处置进行管制,以减少它们可能对水生生态系统和公众健康造成的潜在影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Impact of Green-Synthesized Zinc Oxide Nanoparticles (ZnO NPs) on the Biochemical and Histological Profiles of Cyprinus carpio

Impact of Green-Synthesized Zinc Oxide Nanoparticles (ZnO NPs) on the Biochemical and Histological Profiles of Cyprinus carpio

This study investigated the impact of varying concentrations, including 0.5 mg L−1 (T1), 1 mg L−1 (T2), and 2 mg L−1 (T3) of zinc oxide nanoparticles (ZnO NPs) on hematological, biochemical, and histological indices of Cyprinus carpio. As the use of ZnO NPs grows, there are rising concerns about their potential environmental impacts, particularly on aquatic ecosystems. When released into water bodies, these NPs can be ingested by aquatic organisms, leading to bioaccumulation and potential toxicity. Therefore, understanding their effects on aquatic species, like C. carpio, is crucial. Significant alterations in the erythrocyte count, hemoglobin (Hb), and hematocrit (Ht) levels were found. Compared to the control group, the number of lymphocytes, EOSO, monocytes, and platelets in the Zn NPs-exposed groups dramatically increased. The biochemical analysis found considerable changes in blood total protein, albumin, globulin, and glucose levels. Histological examinations of the gills, intestines, and kidneys were conducted to assess structural or pathological changes. Treated fish showed progressive architectural distortions like necrosis (N), hyperplasia (HP), hypertrophy (HT), fusion of gill lamella (FGL), and proliferation of mucocytes (PM) in gills. Distension of the intercellular space (DIS), increased rate of the mucous cell (IMC), villous atrophy (VA), HP, and dysplasia (DP) were found in the intestines of ZnO NPs treated C. carpio. Tubular dilatation, tubular necrosis, severe congestion, hematopoietic tissue degradation, constricted lumen, glomerulopathy, and bowmans capsule dilution in kidneys of ZnO NPs treated C. carpio were noted. The findings from this study shed light on the biochemical and histological effects of ZnO NPs on C. carpio, contributing to a better understanding of the potential risks associated with NP exposure in aquatic environments. The results highlight the need to regulate the use of these NPs as well as their disposal in order to reduce the potential impact that they could have on aquatic ecosystems and public health.

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来源期刊
Aquaculture Research
Aquaculture Research 农林科学-渔业
CiteScore
4.60
自引率
5.00%
发文量
464
审稿时长
5.3 months
期刊介绍: International in perspective, Aquaculture Research is published 12 times a year and specifically addresses research and reference needs of all working and studying within the many varied areas of aquaculture. The Journal regularly publishes papers on applied or scientific research relevant to freshwater, brackish, and marine aquaculture. It covers all aquatic organisms, floristic and faunistic, related directly or indirectly to human consumption. The journal also includes review articles, short communications and technical papers. Young scientists are particularly encouraged to submit short communications based on their own research.
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